18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

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All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Ransjö M et al. Expression of connexin 43 mRNA in microisolated murine osteoclasts and regulation of bone resorption in vitro by gap junction inhibitors. 2003 Biochem. Biophys. Res. Commun. pmid:12684060
El-Sabban ME et al. ECM-induced gap junctional communication enhances mammary epithelial cell differentiation. 2003 J. Cell. Sci. pmid:12893812
Ye ZC et al. Functional hemichannels in astrocytes: a novel mechanism of glutamate release. 2003 J. Neurosci. pmid:12736329
Solomon IC et al. Blockade of brain stem gap junctions increases phrenic burst frequency and reduces phrenic burst synchronization in adult rat. 2003 J. Neurophysiol. pmid:12522166
Sung YJ et al. Intercellular calcium waves mediate preferential cell growth toward the wound edge in polarized hepatic cells. 2003 Exp. Cell Res. pmid:12837277
Guillotin B et al. Human primary endothelial cells stimulate human osteoprogenitor cell differentiation. 2004 Cell. Physiol. Biochem. pmid:15319536
Seul KH et al. Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis. 2004 Biochem. Biophys. Res. Commun. pmid:15194487
De Blasio BF et al. Global, synchronous oscillations in cytosolic calcium and adherence in bradykinin-stimulated Madin-Darby canine kidney cells. 2004 Acta Physiol. Scand. pmid:15030375
Fujino H and Regan JW Prostaglandin F2alpha amplifies tumor necrosis factor-alpha promoter activity by the FPB prostanoid receptor. 2004 Biochem. Biophys. Res. Commun. pmid:15094384
Thust R et al. Cytogenetic detection of a trans-species bystander effect: induction of sister chromatid exchanges in murine 3T3 cells by ganciclovir metabolized in HSV thymidine kinase gene-transfected Chinese hamster ovary cells. 2004 Mutagenesis pmid:14681310
Garg S et al. Staphylococcus aureus-derived peptidoglycan induces Cx43 expression and functional gap junction intercellular communication in microglia. 2005 J. Neurochem. pmid:16190870
Gumpricht E et al. Licorice compounds glycyrrhizin and 18beta-glycyrrhetinic acid are potent modulators of bile acid-induced cytotoxicity in rat hepatocytes. 2005 J. Biol. Chem. pmid:15642733
Shamekh R et al. The role of connexins in the differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor. 2006 Exp Brain Res pmid:16328273
Miyazato M et al. A gap junction blocker inhibits isolated whole bladder activity in normal rats and rats with partial bladder outlet obstruction. 2006 Biomed. Res. pmid:17099284
Perez Velazquez JL et al. Role of gap junctional coupling in astrocytic networks in the determination of global ischaemia-induced oxidative stress and hippocampal damage. 2006 Eur. J. Neurosci. pmid:16420410
Luna VM and Brehm P An electrically coupled network of skeletal muscle in zebrafish distributes synaptic current. 2006 J. Gen. Physiol. pmid:16801383
Kamijo M et al. The function of connexin 43 on the differentiation of rat bone marrow cells in culture. 2006 Biomed. Res. pmid:17213685
Rodríguez-Sinovas A et al. Protective effect of gap junction uncouplers given during hypoxia against reoxygenation injury in isolated rat hearts. 2006 Am. J. Physiol. Heart Circ. Physiol. pmid:16183732
Guan BC et al. Blockade of gap junction coupling by glycyrrhetinic acids in guinea pig cochlear artery: a whole-cell voltage- and current-clamp study. 2007 Br. J. Pharmacol. pmid:17572704
Lin D et al. Protein kinase C gamma mutations in the C1B domain cause caspase-3-linked apoptosis in lens epithelial cells through gap junctions. 2007 Exp. Eye Res. pmid:17493614