18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

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All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Guan BC et al. Blockade of gap junction coupling by glycyrrhetinic acids in guinea pig cochlear artery: a whole-cell voltage- and current-clamp study. 2007 Br. J. Pharmacol. pmid:17572704
Ikeda Y et al. Role of gap junctions in spontaneous activity of the rat bladder. 2007 Am. J. Physiol. Renal Physiol. pmid:17581924
Lin D et al. Protein kinase C gamma mutations in the C1B domain cause caspase-3-linked apoptosis in lens epithelial cells through gap junctions. 2007 Exp. Eye Res. pmid:17493614
Lang RJ et al. Spontaneous electrical and Ca2+ signals in typical and atypical smooth muscle cells and interstitial cell of Cajal-like cells of mouse renal pelvis. 2007 J. Physiol. (Lond.) pmid:17656432
Luksha L et al. Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites. 2008 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:18032472
Kansui Y et al. Enhanced spontaneous Ca2+ events in endothelial cells reflect signalling through myoendothelial gap junctions in pressurized mesenteric arteries. 2008 Cell Calcium pmid:18191200
Chadjichristos CE et al. Targeting connexin 43 prevents platelet-derived growth factor-BB-induced phenotypic change in porcine coronary artery smooth muscle cells. 2008 Circ. Res. pmid:18239136
Lee CS et al. 18beta-Glycyrrhetinic acid induces apoptotic cell death in SiHa cells and exhibits a synergistic effect against antibiotic anti-cancer drug toxicity. 2008 Life Sci. pmid:18721818
Yamamoto Y et al. Role of gap junctions and protein kinase A during the development of oocyte maturational competence in Ayu (Plecoglossus altivelis). 2008 Gen. Comp. Endocrinol. pmid:17964574
Wu X et al. Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways. 2008 Hepatology pmid:18452148
Ciovacco WA et al. The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. 2009 Bone pmid:18848655
Velasquez Almonacid LA et al. Role of connexin-43 hemichannels in the pathogenesis of Yersinia enterocolitica. 2009 Vet. J. pmid:18824377
Zou Q et al. Simultaneous determination of 18alpha- and 18beta-glycyrrhetic acid in human plasma by LC-ESI-MS and its application to pharmacokinetics. 2009 Biomed. Chromatogr. pmid:18850581
Verma V et al. Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins. 2009 Eur. J. Cell Biol. pmid:18951659
Li WC et al. Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of young Xenopus tadpoles. 2009 J. Physiol. (Lond.) pmid:19221124
He B et al. Tramadol and flurbiprofen depress the cytotoxicity of cisplatin via their effects on gap junctions. 2009 Clin. Cancer Res. pmid:19723651
Pellati D et al. In vitro effects of glycyrrhetinic acid on the growth of clinical isolates of Candida albicans. 2009 Phytother Res pmid:19067381
Ming J et al. Regulatory effects of myoendothelial gap junction on vascular reactivity after hemorrhagic shock in rats. 2009 Shock pmid:19077877
Nejime N et al. Possible participation of chloride ion channels in ATP release from cancer cells in suspension. 2009 Clin. Exp. Pharmacol. Physiol. pmid:18986334
Trepel M et al. A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. 2009 Mol. Cancer Ther. pmid:19671758