18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

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All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Cavone L et al. 18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis. 2011 Ocul. Immunol. Inflamm. pmid:21426233
Ma KT et al. [18β-glycyrrhetinic acid inhibits outward current of vascular smooth muscle cells of arterioles]. 2011 Sheng Li Xue Bao pmid:22193450
Ukil A et al. Curative effect of 18β-glycyrrhetinic acid in experimental visceral leishmaniasis depends on phosphatase-dependent modulation of cellular MAP kinases. 2011 PLoS ONE pmid:22194991
Yu J et al. Disruption of gap junctions reduces biomarkers of decidualization and angiogenesis and increases inflammatory mediators in human endometrial stromal cell cultures. 2011 Mol. Cell. Endocrinol. pmid:21767601
Autsavapromporn N et al. Intercellular communication amplifies stressful effects in high-charge, high-energy (HZE) particle-irradiated human cells. 2011 J. Radiat. Res. pmid:21905305
Dey A et al. Role of connexin 43 in the maintenance of spontaneous activity in the guinea pig prostate gland. 2010 Br. J. Pharmacol. pmid:20735413
Song D et al. Connexin 43 hemichannel regulates H9c2 cell proliferation by modulating intracellular ATP and [Ca2+]. 2010 Acta Biochim. Biophys. Sin. (Shanghai) pmid:20705586
Sasaki H et al. 18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice. 2010 J. Periodont. Res. pmid:20682015
Li WC et al. Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors. 2010 J. Neurosci. pmid:21148000
Geddawy A et al. Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery. 2010 J. Pharmacol. Sci. pmid:20838025
Kao TC et al. Glycyrrhizic acid and 18beta-glycyrrhetinic acid inhibit inflammation via PI3K/Akt/GSK3beta signaling and glucocorticoid receptor activation. 2010 J. Agric. Food Chem. pmid:20681651
Verwey LJ and Edwards TM Gap junctions and memory: an investigation using a single trial discrimination avoidance task for the neonate chick. 2010 Neurobiol Learn Mem pmid:19796702
Xiao Y et al. 18Beta-glycyrrhetinic acid ameliorates acute Propionibacterium acnes-induced liver injury through inhibition of macrophage inflammatory protein-1alpha. 2010 J. Biol. Chem. pmid:19897483
Plotnikov EY et al. Cytoplasm and organelle transfer between mesenchymal multipotent stromal cells and renal tubular cells in co-culture. 2010 Exp. Cell Res. pmid:20599955
Lee CS et al. 18β-Glycyrrhetinic acid potentiates apoptotic effect of trichostatin A on human epithelial ovarian carcinoma cell lines. 2010 Eur. J. Pharmacol. pmid:20868669
Kapeta S et al. Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts. 2010 J. Biol. Chem. pmid:20068043
Li XD et al. Panax notoginseng saponins potentiate osteogenesis of bone marrow stromal cells by modulating gap junction intercellular communication activities. 2010 Cell. Physiol. Biochem. pmid:21220939
Kawakami Z et al. Glycyrrhizin and its metabolite 18 beta-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan, ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytes. 2010 Eur. J. Pharmacol. pmid:19818347
Pellati D et al. In vitro effects of glycyrrhetinic acid on the growth of clinical isolates of Candida albicans. 2009 Phytother Res pmid:19067381
Ming J et al. Regulatory effects of myoendothelial gap junction on vascular reactivity after hemorrhagic shock in rats. 2009 Shock pmid:19077877