18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

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All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Ciovacco WA et al. The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. 2009 Bone pmid:18848655
Velasquez Almonacid LA et al. Role of connexin-43 hemichannels in the pathogenesis of Yersinia enterocolitica. 2009 Vet. J. pmid:18824377
Ye ZC et al. Pharmacological "cross-inhibition" of connexin hemichannels and swelling activated anion channels. 2009 Glia pmid:18837047
Zou Q et al. Simultaneous determination of 18alpha- and 18beta-glycyrrhetic acid in human plasma by LC-ESI-MS and its application to pharmacokinetics. 2009 Biomed. Chromatogr. pmid:18850581
Verma V et al. Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins. 2009 Eur. J. Cell Biol. pmid:18951659
Li WC et al. Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of young Xenopus tadpoles. 2009 J. Physiol. (Lond.) pmid:19221124
He B et al. Tramadol and flurbiprofen depress the cytotoxicity of cisplatin via their effects on gap junctions. 2009 Clin. Cancer Res. pmid:19723651
Pellati D et al. In vitro effects of glycyrrhetinic acid on the growth of clinical isolates of Candida albicans. 2009 Phytother Res pmid:19067381
Miguel-Hidalgo J et al. Infusion of gliotoxins or a gap junction blocker in the prelimbic cortex increases alcohol preference in Wistar rats. 2009 J. Psychopharmacol. (Oxford) pmid:18562436
Nejime N et al. Possible participation of chloride ion channels in ATP release from cancer cells in suspension. 2009 Clin. Exp. Pharmacol. Physiol. pmid:18986334
Trepel M et al. A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. 2009 Mol. Cancer Ther. pmid:19671758
Dey A et al. Role of connexin 43 in the maintenance of spontaneous activity in the guinea pig prostate gland. 2010 Br. J. Pharmacol. pmid:20735413
Song D et al. Connexin 43 hemichannel regulates H9c2 cell proliferation by modulating intracellular ATP and [Ca2+]. 2010 Acta Biochim. Biophys. Sin. (Shanghai) pmid:20705586
Sasaki H et al. 18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice. 2010 J. Periodont. Res. pmid:20682015
Li WC et al. Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors. 2010 J. Neurosci. pmid:21148000
Geddawy A et al. Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery. 2010 J. Pharmacol. Sci. pmid:20838025
Verwey LJ and Edwards TM Gap junctions and memory: an investigation using a single trial discrimination avoidance task for the neonate chick. 2010 Neurobiol Learn Mem pmid:19796702
Plotnikov EY et al. Cytoplasm and organelle transfer between mesenchymal multipotent stromal cells and renal tubular cells in co-culture. 2010 Exp. Cell Res. pmid:20599955
Li XD et al. Panax notoginseng saponins potentiate osteogenesis of bone marrow stromal cells by modulating gap junction intercellular communication activities. 2010 Cell. Physiol. Biochem. pmid:21220939
Kawakami Z et al. Glycyrrhizin and its metabolite 18 beta-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan, ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytes. 2010 Eur. J. Pharmacol. pmid:19818347