18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Sun W et al. Design, synthesis, and sustained-release property of 1,3-cyclic propanyl phosphate ester of 18β-glycyrrhetinic acid. 2011 Chem Biol Drug Des pmid:21244638
Li XD et al. Panax notoginseng saponins potentiate osteogenesis of bone marrow stromal cells by modulating gap junction intercellular communication activities. 2010 Cell. Physiol. Biochem. pmid:21220939
Piao H et al. Effects of connexin-mimetic peptides on perfusion pressure in response to phenylephrine in isolated, perfused rat kidneys. 2011 Clin. Exp. Nephrol. pmid:21153751
Li WC et al. Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors. 2010 J. Neurosci. pmid:21148000
Lee CS et al. 18β-Glycyrrhetinic acid potentiates apoptotic effect of trichostatin A on human epithelial ovarian carcinoma cell lines. 2010 Eur. J. Pharmacol. pmid:20868669
Geddawy A et al. Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery. 2010 J. Pharmacol. Sci. pmid:20838025
Dey A et al. Role of connexin 43 in the maintenance of spontaneous activity in the guinea pig prostate gland. 2010 Br. J. Pharmacol. pmid:20735413
Song D et al. Connexin 43 hemichannel regulates H9c2 cell proliferation by modulating intracellular ATP and [Ca2+]. 2010 Acta Biochim. Biophys. Sin. (Shanghai) pmid:20705586
Sasaki H et al. 18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice. 2010 J. Periodont. Res. pmid:20682015
Kao TC et al. Glycyrrhizic acid and 18beta-glycyrrhetinic acid inhibit inflammation via PI3K/Akt/GSK3beta signaling and glucocorticoid receptor activation. 2010 J. Agric. Food Chem. pmid:20681651
Plotnikov EY et al. Cytoplasm and organelle transfer between mesenchymal multipotent stromal cells and renal tubular cells in co-culture. 2010 Exp. Cell Res. pmid:20599955
Kapeta S et al. Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts. 2010 J. Biol. Chem. pmid:20068043
Xiao Y et al. 18Beta-glycyrrhetinic acid ameliorates acute Propionibacterium acnes-induced liver injury through inhibition of macrophage inflammatory protein-1alpha. 2010 J. Biol. Chem. pmid:19897483
Kawakami Z et al. Glycyrrhizin and its metabolite 18 beta-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan, ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytes. 2010 Eur. J. Pharmacol. pmid:19818347
Verwey LJ and Edwards TM Gap junctions and memory: an investigation using a single trial discrimination avoidance task for the neonate chick. 2010 Neurobiol Learn Mem pmid:19796702
He B et al. Tramadol and flurbiprofen depress the cytotoxicity of cisplatin via their effects on gap junctions. 2009 Clin. Cancer Res. pmid:19723651
Trepel M et al. A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. 2009 Mol. Cancer Ther. pmid:19671758
Classen-Houben D et al. Selective inhibition of 11beta-hydroxysteroid dehydrogenase 1 by 18alpha-glycyrrhetinic acid but not 18beta-glycyrrhetinic acid. 2009 J. Steroid Biochem. Mol. Biol. pmid:19429429
Kaneda M et al. Direct formation of proteo-liposomes by in vitro synthesis and cellular cytosolic delivery with connexin-expressing liposomes. 2009 Biomaterials pmid:19423159
Iqbal Choudhary M et al. Microbial transformation of 18beta-glycyrrhetinic acid by Cunninghamella elegans and Fusarium lini, and lipoxygenase inhibitory activity of transformed products. 2009 Nat. Prod. Res. pmid:19384727