Beta-boswellic acid

Beta-boswellic acid is a lipid of Prenol Lipids (PR) class.

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Current reference collection contains 467 references associated with Beta-boswellic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
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Glaser T et al. Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity. 1999 Br. J. Cancer pmid:10360653
Syrovets T et al. Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha. 2000 Mol. Pharmacol. pmid:10860928
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Gupta OP et al. A sensitive and relevant model for evaluating anti-inflammatory activity-papaya latex-induced rat paw inflammation. 1992 J Pharmacol Toxicol Methods pmid:1392054
Altmann A et al. Coupling of boswellic acid-induced Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. 2004 Br. J. Pharmacol. pmid:14691050
Kiela PR et al. Effects of Boswellia serrata in mouse models of chemically induced colitis. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15539433
Syrovets T et al. Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-alpha induction in monocytes by direct interaction with IkappaB kinases. 2005 J. Immunol. pmid:15611276
Xia L et al. Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells. 2005 Mol. Cancer Ther. pmid:15767547
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Chevrier MR et al. Boswellia carterii extract inhibits TH1 cytokines and promotes TH2 cytokines in vitro. 2005 Clin. Diagn. Lab. Immunol. pmid:15879017
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Poeckel D et al. Induction of central signalling pathways and select functional effects in human platelets by beta-boswellic acid. 2005 Br. J. Pharmacol. pmid:16086030
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Anthoni C et al. Mechanisms underlying the anti-inflammatory actions of boswellic acid derivatives in experimental colitis. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16423918
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Poeckel D et al. Boswellic acids stimulate arachidonic acid release and 12-lipoxygenase activity in human platelets independent of Ca2+ and differentially interact with platelet-type 12-lipoxygenase. 2006 Mol. Pharmacol. pmid:16788089
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Scherz H et al. CEC and EKC of natural compounds. 2007 Electrophoresis pmid:17450533
Khanna D et al. Natural products as a gold mine for arthritis treatment. 2007 Curr Opin Pharmacol pmid:17475558
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Kunnumakkara AB et al. Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1. 2009 Mol. Cancer Res. pmid:19147543
Siemoneit U et al. On the interference of boswellic acids with 5-lipoxygenase: mechanistic studies in vitro and pharmacological relevance. 2009 Eur. J. Pharmacol. pmid:19374837
Tausch L et al. Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense. 2009 J. Immunol. pmid:19648270
Liu JJ and Duan RD LY294002 enhances boswellic acid-induced apoptosis in colon cancer cells. 2009 Anticancer Res. pmid:19661305
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Zhang Y and Duan RD Boswellic acid inhibits expression of acid sphingomyelinase in intestinal cells. 2009 Lipids Health Dis pmid:19951413
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Lakka A et al. Isolation of hypoxia-inducible factor 1 (HIF-1) inhibitors from frankincense using a molecularly imprinted polymer. 2011 Invest New Drugs pmid:20437079
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Siemoneit U et al. Inhibition of microsomal prostaglandin E2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense. 2011 Br. J. Pharmacol. pmid:20840544
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Kirste S et al. Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. 2011 Cancer pmid:21287538
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Shen Y et al. Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells. 2012 Cancer Biol. Ther. pmid:22415137
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Rao AR et al. In vitro and in vivo inhibitory activities of four Indian medicinal plant extracts and their major components on rat aldose reductase and generation of advanced glycation endproducts. 2013 Phytother Res pmid:22826152
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Takahashi M et al. Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family. 2012 Carcinogenesis pmid:22983985
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Karima O et al. An in vitro study of the role of β-boswellic acid in the microtubule assembly dynamics. 2012 FEBS Lett. pmid:23098754
Suneela D and Dipmala P Synthesis and pharmacokinetic profile of rhein- boswellic acid conjugate. 2012 Bioorg. Med. Chem. Lett. pmid:23107483
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Sabina EP et al. Efficacy of boswellic acid on lysosomal acid hydrolases, lipid peroxidation and anti-oxidant status in gouty arthritic mice. 2012 Asian Pac J Trop Biomed pmid:23569882
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Dhaneshwar S et al. Disease-modifying effect of anthraquinone prodrug with boswellic acid on collagenase-induced osteoarthritis in Wistar rats. 2013 Inflamm Allergy Drug Targets pmid:23701173
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Tibaldi E et al. The tyrosine phosphatase SHP-1 inhibits proliferation of activated hepatic stellate cells by impairing PDGF receptor signaling. 2014 Biochim. Biophys. Acta pmid:24140598
Wang Q et al. Oral and topical boswellic acid attenuates mouse osteoarthritis. 2014 Osteoarthr. Cartil. pmid:24185109
Nieman DC et al. A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial. 2013 Nutr J pmid:24274358
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Verhoff M et al. Tetra- and pentacyclic triterpene acids from the ancient anti-inflammatory remedy frankincense as inhibitors of microsomal prostaglandin E(2) synthase-1. 2014 J. Nat. Prod. pmid:24844534
Liu M et al. A boswellic acid-containing extract ameliorates schistosomiasis liver granuloma and fibrosis through regulating NF-κB signaling in mice. 2014 PLoS ONE pmid:24941000
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Baeten J et al. Holy smoke in medieval funerary rites: chemical fingerprints of frankincense in southern Belgian incense burners. 2014 PLoS ONE pmid:25391130
Pathania AS et al. The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors. 2015 Mol. Cancer pmid:25608686
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Toden S et al. Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer. 2015 Cancer Prev Res (Phila) pmid:25712055
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Liu Z et al. Boswellic acid attenuates asthma phenotypes by downregulation of GATA3 via pSTAT6 inhibition in a murine model of asthma. 2015 Int J Clin Exp Pathol pmid:25755710