Maslinic acid

Maslinic acid is a lipid of Prenol Lipids (PR) class.

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Current reference collection contains 541 references associated with Maslinic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Yadav VR et al. Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer. 2010 Toxins (Basel) pmid:22069560
Sun Z et al. Identification and determination of carboxylic acids in food samples using 2-(2-(anthracen-10-yl)-1H-phenanthro[9,10-d]imidazol-1-yl)ethyl 4-methylbenzenesulfonate (APIETS) as labeling reagent by HPLC with FLD and APCI/MS. 2011 Talanta pmid:21726743
Wang X et al. Effects and possible mechanisms of action of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer's disease. 2015 Sci Rep pmid:26530776
Reyes-Zurita FJ et al. Maslinic Acid, a Natural Triterpene, Induces a Death Receptor-Mediated Apoptotic Mechanism in Caco-2 p53-Deficient Colon Adenocarcinoma Cells. 2016 PLoS ONE pmid:26751572
Sánchez-Tena S et al. Maslinic acid-enriched diet decreases intestinal tumorigenesis in Apc(Min/+) mice through transcriptomic and metabolomic reprogramming. 2013 PLoS ONE pmid:23527181
Martín R et al. Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation. 2009 PLoS ONE pmid:19543395
Hsum YW et al. Cancer chemopreventive activity of maslinic acid: suppression of COX-2 expression and inhibition of NF-κB and AP-1 activation in Raji cells. 2011 Planta Med. pmid:20669087
Kim YK et al. Cytotoxic triterpenes from stem bark of Physocarpus intermedius. 2000 Planta Med. pmid:10909277
Kim E et al. Isolation and identification of intestinal CYP3A inhibitors from cranberry (Vaccinium macrocarpon) using human intestinal microsomes. 2011 Planta Med. pmid:20717876
Sultana N and Lee NH Antielastase and free radical scavenging activities of compounds from the stems of Cornus kousa. 2007 Phytother Res pmid:17661332
Martinez A et al. Biotransformation of oleanolic and maslinic acids by Rhizomucor miehei. 2013 Phytochemistry pmid:23790643
Goulas V and Manganaris GA Towards an efficient protocol for the determination of triterpenic acids in olive fruit: a comparative study of drying and extraction methods. 2012 Sep-Oct Phytochem Anal pmid:22213569
Prajapati MS et al. Leucas aspera: A review. 2010 Pharmacogn Rev pmid:22228946
Cho J et al. Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. 2015 Oncotarget pmid:26513295
Liu J et al. Effect of olive pomace extracts on hyperlipidaemia. 2011 Nat. Prod. Res. pmid:21740285
Chaudhuri PK and Singh D A new triterpenoid from the rhizomes of Nelumbo nucifera. 2013 Nat. Prod. Res. pmid:22512662
Huang B et al. [Protective effect of maslinic acid preconditioning against oxygen-glucose deprivation- induced injuries in embryonic rat cortical neurons]. 2013 Nan Fang Yi Ke Da Xue Xue Bao pmid:23529224
Zhai B et al. Antimalarial evaluation of the chemical constituents of hairy root culture of Bixa orellana L. 2013 Molecules pmid:24406786
Fan H et al. Chemical constituents with free-radical-scavenging activities from the stem of Microcos paniculata. 2010 Molecules pmid:20714312
Qian Y et al. Neuroprotection by Combined Administration with Maslinic Acid, a Natural Product from Olea europaea, and MK-801 in the Cerebral Ischemia Model. 2016 Molecules pmid:27548129
Hsia TC et al. Maslinic acid induces mitochondrial apoptosis and suppresses HIF-1α expression in A549 lung cancer cells under normoxic and hypoxic conditions. 2014 Molecules pmid:25460312
Lozano-Mena G et al. Maslinic acid, a natural phytoalexin-type triterpene from olives--a promising nutraceutical? 2014 Molecules pmid:25093990
Li C et al. Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway. 2010 Mol. Cancer pmid:20367887
Lou-Bonafonte JM et al. Efficacy of bioactive compounds from extra virgin olive oil to modulate atherosclerosis development. 2012 Mol Nutr Food Res pmid:22760979
Bai X et al. Effects of maslinic acid on the proliferation and apoptosis of A549 lung cancer cells. 2016 Mol Med Rep pmid:26572558
Moneriz C et al. Parasitostatic effect of maslinic acid. II. Survival increase and immune protection in lethal Plasmodium yoelii-infected mice. 2011 Malar. J. pmid:21518429
Moneriz C et al. Parasitostatic effect of maslinic acid. I. Growth arrest of Plasmodium falciparum intraerythrocytic stages. 2011 Malar. J. pmid:21477369
García-Granados A et al. Epoxides, cyclic sulfites, and sulfate from natural pentacyclic triterpenoids: theoretical calculations and chemical transformations. 2003 J. Org. Chem. pmid:12790588
Villar VH et al. Oleanolic and maslinic acid sensitize soft tissue sarcoma cells to doxorubicin by inhibiting the multidrug resistance protein MRP-1, but not P-glycoprotein. 2014 J. Nutr. Biochem. pmid:24491315
Juan ME et al. Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells. 2006 J. Nutr. pmid:16988125
Cheng K et al. Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase. 2008 J. Nat. Prod. pmid:18847277
Xu HX et al. Anti-HIV triterpene acids from Geum japonicum. 1996 J. Nat. Prod. pmid:8759159
Acebey-Castellon IL et al. Triterpenoid saponins from Symplocos lancifolia. 2011 J. Nat. Prod. pmid:21288041
Wen X et al. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies. 2008 J. Med. Chem. pmid:18517260
Li C et al. Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways. 2011 J. Bone Miner. Res. pmid:20814972
Allouche Y et al. Triterpenic content and chemometric analysis of virgin olive oils from forty olive cultivars. 2009 J. Agric. Food Chem. pmid:19326867
Li GL et al. Development of a new HPLC method with precolumn fluorescent derivatization for rapid, selective and sensitive detection of triterpenic acids in fruits. 2011 J. Agric. Food Chem. pmid:21388126
Lin CC et al. Antiangiogenic potential of three triterpenic acids in human liver cancer cells. 2011 J. Agric. Food Chem. pmid:21175131
Guo S et al. Simultaneous qualitative and quantitative analysis of triterpenic acids, saponins and flavonoids in the leaves of two Ziziphus species by HPLC-PDA-MS/ELSD. 2011 J Pharm Biomed Anal pmid:21665400
Hussain Shaik A et al. Maslinic acid protects against isoproterenol-induced cardiotoxicity in albino Wistar rats. 2012 J Med Food pmid:22846081
Stiti N and Hartmann MA Nonsterol Triterpenoids as Major Constituents of Olea europaea. 2012 J Lipids pmid:22523691
Wang HM et al. Four new triterpenoids isolated from the resin of Garcinia hanburyi. 2014 J Asian Nat Prod Res pmid:24392659
Al-Jaber HI et al. New terpenes from Salvia palaestina Benth. and Salvia syriaca L. growing wild in Jordan. 2012 J Asian Nat Prod Res pmid:22574636
Peragón J et al. A New HPLC-MS Method for Measuring Maslinic Acid and Oleanolic Acid in HT29 and HepG2 Human Cancer Cells. 2015 Int J Mol Sci pmid:26370984
Song FL et al. Total phenolic contents and antioxidant capacities of selected chinese medicinal plants. 2010 Int J Mol Sci pmid:20640157
Politi FA et al. Antimicrobial, cytotoxic and antioxidant activities and determination of the total tannin content of bark extracts Endopleura uchi. 2011 Int J Mol Sci pmid:21731469
Allouche Y et al. Antioxidant and antiatherogenic activities of pentacyclic triterpenic diols and acids. 2010 Food Chem. Toxicol. pmid:20650302
Caligiani A et al. A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients. 2013 Food Chem pmid:23122121
Wang R et al. Constituents of the flowers of Punica granatum. 2006 Fitoterapia pmid:16887296
Reyes FJ et al. (2Alpha,3beta)-2,3-dihydroxyolean-12-en-28-oic acid, a new natural triterpene from Olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells. 2006 FEBS Lett. pmid:17083937