G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

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All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Zhu Y et al. [Effects of GM3 on proliferation, apoptosis and VEGF expression in human lung adenocarcinoma cell line A549 cells]. 2011 Zhonghua Zhong Liu Za Zhi pmid:21575493
Uemura S [The regulation of ganglioside GM3 synthesis]. 2012 Yakugaku Zasshi pmid:22864347
Kabayama K [Modulation of growth factor receptors in membrane microdomains]. 2012 Yakugaku Zasshi pmid:22465916
Inokuchi J Insulin resistance as a membrane microdomain disorder. 2007 Yakugaku Zasshi pmid:17409686
Miklavcic JJ et al. Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease. 2015 World J. Gastroenterol. pmid:26401073
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Wang H et al. Antitumor effects of exogenous ganglioside GM3 on bladder cancer in an orthotopic cancer model. 2013 Urology pmid:23102779
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Brønnum H et al. Milk-derived GM(3) and GD(3) differentially inhibit dendritic cell maturation and effector functionalities. 2005 Scand. J. Immunol. pmid:15963050
Sørensen LK A liquid chromatography/tandem mass spectrometric approach for the determination of gangliosides GD3 and GM3 in bovine milk and infant formulae. 2006 Rapid Commun. Mass Spectrom. pmid:17094170
Chen S et al. Quantitative analysis of the molecular species of monosialogangliosides by continuous-flow fast-atom bombardment mass spectrometry. 1991 Rapid Commun. Mass Spectrom. pmid:1811797
Langeveld M and Aerts JM Glycosphingolipids and insulin resistance. Prog. Lipid Res. pmid:19303901
Yu S et al. Binding of rainbow trout sperm to egg is mediated by strong carbohydrate-to-carbohydrate interaction between (KDN)GM3 (deaminated neuraminyl ganglioside) and Gg3-like epitope. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:11880637