G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Oda M et al. Bacillus cereus sphingomyelinase recognizes ganglioside GM3. 2013 Biochem. Biophys. Res. Commun. pmid:23313504
Iskarpatyoti JA et al. Serotype-specific differences in inhibition of reovirus infectivity by human-milk glycans are determined by viral attachment protein σ1. 2012 Virology pmid:22999096
Uemura S [The regulation of ganglioside GM3 synthesis]. 2012 Yakugaku Zasshi pmid:22864347
Tsukuda Y et al. Ganglioside GM3 has an essential role in the pathogenesis and progression of rheumatoid arthritis. 2012 PLoS ONE pmid:22768242
Spessott W et al. Glycosyltransferase complexes improve glycolipid synthesis. 2012 FEBS Lett. pmid:22687240
Zhong Y et al. N-Glycolyl GM3 ganglioside immunoexpression in oral mucosal melanomas of Chinese. 2012 Oral Dis pmid:22574836
Papini N et al. MmNEU3 sialidase over-expression in C2C12 myoblasts delays differentiation and induces hypertrophic myotube formation. 2012 J. Cell. Biochem. pmid:22552967
Qiu L et al. Combining synthetic carbohydrate vaccines with cancer cell glycoengineering for effective cancer immunotherapy. 2012 Cancer Immunol. Immunother. pmid:22539085
Puryear WB et al. HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22529395
Dawson G et al. Abnormal gangliosides are localized in lipid rafts in Sanfilippo (MPS3a) mouse brain. 2012 Neurochem. Res. pmid:22484966