G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Bobryshev YV et al. Incorporation and localisation of ganglioside GM3 in human intimal atherosclerotic lesions. 1997 Biochim. Biophys. Acta pmid:9375803
Mikhailenko IA et al. Interaction of low-density lipoproteins with gangliosides. 1991 Biochim. Biophys. Acta pmid:1911863
Fidelio GD et al. Molecular parameters and physical state of neutral glycosphingolipids and gangliosides in monolayers at different temperatures. 1986 Biochim. Biophys. Acta pmid:3942728
Sarkar CP and Cenedella RJ Gangliosides in normal and cataractous lenses of several species. 1982 Biochim. Biophys. Acta pmid:7104379
Haga Y et al. Effect of lipid mimetics of GM3 and lyso-GM3 dimer on EGF receptor tyrosine kinase and EGF-induced signal transduction. 2008 Biochim. Biophys. Acta pmid:18036568
Bouhours D et al. GM3 and GD3 are the major gangliosides of rat fetal intestine. 1982 Biochim. Biophys. Acta pmid:7150616
Lockney MW and Sweeley CC Characterization of a glycosphingolipid beta-N-acetylgalactosaminyl-transferase activity in cultured hamster (nil) cells. 1982 Biochim. Biophys. Acta pmid:6812637
Bouhours JF and Glickman RM Rat intestinal glycolipids. III. Fatty acids and long chain bases of glycolipids from villus and crypt cells. 1977 Biochim. Biophys. Acta pmid:870058
Ardail D et al. Subcellular distribution and metabolic fate of exogenous ceramides taken up by HL-60 cells. 2002 Biochim. Biophys. Acta pmid:12176398
Dahiya R et al. Estrogen-induced alterations of the acidic and neutral glycosphingolipids of rat kidney. 1988 Biochim. Biophys. Acta pmid:3167091