| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Song WX et al. | Effects of gangliosides GM3 and De-N-acetyl GM3 on epidermal growth factor receptor kinase activity and cell growth. | 1991 | J. Biol. Chem. | pmid:1645342 |
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| Choi HJ et al. | Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway. | 2006 | Glycobiology | pmid:16574813 |
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| Barbat C et al. | p56lck, LFA-1 and PI3K but not SHP-2 interact with GM1- or GM3-enriched microdomains in a CD4-p56lck association-dependent manner. | 2007 | Biochem. J. | pmid:17123354 |
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| Kang SK et al. | Disialoganglioside GD3 increases in the secretion of apoB-containing lipoproteins. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17368571 |
| Fujita A et al. | Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling. | 2007 | Mol. Biol. Cell | pmid:17392511 |
| Inokuchi J | Insulin resistance as a membrane microdomain disorder. | 2007 | Yakugaku Zasshi | pmid:17409686 |
| Janich P and Corbeil D | GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells. | 2007 | FEBS Lett. | pmid:17428477 |
| Azuma Y et al. | Recombinant human hexamer-dominant IgM monoclonal antibody to ganglioside GM3 for treatment of melanoma. | 2007 | Clin. Cancer Res. | pmid:17473208 |
| Milani S et al. | Ganglioside GM(3) is stably associated to tyrosine-phosphorylated ErbB2/EGFR receptor complexes and EGFR monomers, but not to ErbB2. | 2007 | Biochim. Biophys. Acta | pmid:17521961 |
| Roperto S et al. | Sialic acid and GM3 ganglioside expression in papillomavirus-associated urinary bladder tumours of cattle with chronic enzootic haematuria. | J. Comp. Pathol. | pmid:17624364 | |
| Hidari KI et al. | Binding kinetics of influenza viruses to sialic acid-containing carbohydrates. | 2007 | Glycoconj. J. | pmid:17624609 |
| Murozuka Y et al. | Lyso-GM3, its dimer, and multimer: their synthesis, and their effect on epidermal growth factor-induced receptor tyrosine kinase. | 2007 | Glycoconj. J. | pmid:17638075 |
| Gracheva EV et al. | Activation of ganglioside GM3 biosynthesis in human monocyte/macrophages during culturing in vitro. | 2007 | Biochemistry Mosc. | pmid:17680770 |
| Kabayama K et al. | Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17699617 |
| Toma L et al. | Synthesis, conformational studies, binding assessment and liposome insertion of a thioether-bridged mimetic of the antigen GM3 ganglioside lactone. | 2007 | Chembiochem | pmid:17705308 |
| Noguchi M et al. | GM3 synthase gene is a novel biomarker for histological classification and drug sensitivity against epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. | 2007 | Cancer Sci. | pmid:17711504 |
| Sega M et al. | Short-range structure of a GM3 ganglioside membrane: comparison between experimental WAXS and computer simulation results. | 2007 | J Phys Chem B | pmid:17718468 |
| Azuma Y et al. | Enhanced expression of membrane-associated sialidase Neu3 decreases GD3 and increases GM3 on the surface of Jurkat cells during etoposide-induced apoptosis. | 2007 | Biol. Pharm. Bull. | pmid:17827720 |
| Crawley AC and Walkley SU | Developmental analysis of CNS pathology in the lysosomal storage disease alpha-mannosidosis. | 2007 | J. Neuropathol. Exp. Neurol. | pmid:17882013 |
| Wang Q et al. | Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell. | 2007 | Bioorg. Med. Chem. | pmid:17892942 |
| Stepanenko RN et al. | A conjugate of an oligosaccharide fragment of tumor-associated ganglioside antigen with hemocyanin is a prototype antitumor vaccine. | Dokl. Biol. Sci. | pmid:17929671 | |
| Wang XQ et al. | Suppression of epidermal growth factor receptor signaling by protein kinase C-alpha activation requires CD82, caveolin-1, and ganglioside. | 2007 | Cancer Res. | pmid:17942932 |
| Haga Y et al. | Effect of lipid mimetics of GM3 and lyso-GM3 dimer on EGF receptor tyrosine kinase and EGF-induced signal transduction. | 2008 | Biochim. Biophys. Acta | pmid:18036568 |
| Kato T et al. | Purification by centrifugal partition chromatography of amphiphilic compounds, glycolipids and pseudo-glycolipids synthesized by using cells. | 2008 | J Chromatogr A | pmid:18082172 |
| Langeveld M et al. | Type I Gaucher disease, a glycosphingolipid storage disorder, is associated with insulin resistance. | 2008 | J. Clin. Endocrinol. Metab. | pmid:18089699 |
| Chen S et al. | Quantitative analysis of the molecular species of monosialogangliosides by continuous-flow fast-atom bombardment mass spectrometry. | 1991 | Rapid Commun. Mass Spectrom. | pmid:1811797 |
| Park JE et al. | Fine specificity of natural killer T cells against GD3 ganglioside and identification of GM3 as an inhibitory natural killer T-cell ligand. | 2008 | Immunology | pmid:18154620 |
| Ghauharali-van der Vlugt K et al. | Prominent increase in plasma ganglioside GM3 is associated with clinical manifestations of type I Gaucher disease. | 2008 | Clin. Chim. Acta | pmid:18164265 |
| Todeschini AR et al. | Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18272501 |
| Mukherjee P et al. | Thematic review series: sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a. | 2008 | J. Lipid Res. | pmid:18287616 |
| de León J et al. | Differential influence of the tumour-specific non-human sialic acid containing GM3 ganglioside on CD4+CD25- effector and naturally occurring CD4+CD25+ regulatory T cells function. | 2008 | Int. Immunol. | pmid:18310617 |
| Dyatlovitskaya EV et al. | Influence of ganglioside GM3 and its breakdown products on lymphoblastic transformation and T-suppressor activity. | 1991 | Eur. J. Biochem. | pmid:1831126 |
| Choi HJ et al. | The AP-2alpha transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene. | 2008 | Glycobiology | pmid:18316341 |
| Jin UH et al. | Membrane type sialidase inhibits the megakaryocytic differentiation of human leukemia K562 cells. | 2008 | Biochim. Biophys. Acta | pmid:18339327 |
| Mazorra Z et al. | Immunization with a GM3 ganglioside nanoparticulated vaccine confers an effector CD8(+) T cells-mediated protection against melanoma B16 challenge. | 2008 | Cancer Immunol. Immunother. | pmid:18351335 |
| Liu Y et al. | Efficient synthesis of a sialic acid alpha(2-->3)galactose building block and its application to the synthesis of ganglioside GM3. | 2008 | J. Org. Chem. | pmid:18433175 |
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| Wang P et al. | GM3 signals regulating TNF-alpha expression are mediated by Rictor and Arhgdib in mouse melanoma B16 cells. | 2007 | Oncology | pmid:18523362 |
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| pmid:18828994 | ||||
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G(M3) Ganglioside
G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.
Cross Reference
Introduction
To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with G(M3) Ganglioside?
G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with G(M3) Ganglioside
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with G(M3) Ganglioside?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with G(M3) Ganglioside?
There are no associated biomedical information in the current reference collection.