| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mukherjee P et al. | Thematic review series: sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a. | 2008 | J. Lipid Res. | pmid:18287616 |
| Li H et al. | GM2/GD2 and GM3 gangliosides have no effect on cellular cholesterol pools or turnover in normal or NPC1 mice. | 2008 | J. Lipid Res. | pmid:18450647 |
| Nagai K et al. | Higher expression of renal sulfoglycolipids in marine mammals. | 2008 | Glycoconj. J. | pmid:18470608 |
| Liu Y et al. | Efficient synthesis of a sialic acid alpha(2-->3)galactose building block and its application to the synthesis of ganglioside GM3. | 2008 | J. Org. Chem. | pmid:18433175 |
| Mazorra Z et al. | Immunization with a GM3 ganglioside nanoparticulated vaccine confers an effector CD8(+) T cells-mediated protection against melanoma B16 challenge. | 2008 | Cancer Immunol. Immunother. | pmid:18351335 |
| Choi HJ et al. | The AP-2alpha transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene. | 2008 | Glycobiology | pmid:18316341 |
| de León J et al. | Differential influence of the tumour-specific non-human sialic acid containing GM3 ganglioside on CD4+CD25- effector and naturally occurring CD4+CD25+ regulatory T cells function. | 2008 | Int. Immunol. | pmid:18310617 |
| Ghauharali-van der Vlugt K et al. | Prominent increase in plasma ganglioside GM3 is associated with clinical manifestations of type I Gaucher disease. | 2008 | Clin. Chim. Acta | pmid:18164265 |
| Park JE et al. | Fine specificity of natural killer T cells against GD3 ganglioside and identification of GM3 as an inhibitory natural killer T-cell ligand. | 2008 | Immunology | pmid:18154620 |
| Kim SM et al. | Effects of gangliosides on the differentiation of human mesenchymal stem cells into osteoblasts by modulating epidermal growth factor receptors. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18471991 |
| Todeschini AR et al. | Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18272501 |
| Jin UH et al. | Membrane type sialidase inhibits the megakaryocytic differentiation of human leukemia K562 cells. | 2008 | Biochim. Biophys. Acta | pmid:18339327 |
| Janich P and Corbeil D | GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells. | 2007 | FEBS Lett. | pmid:17428477 |
| Kang SK et al. | Disialoganglioside GD3 increases in the secretion of apoB-containing lipoproteins. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17368571 |
| Barbat C et al. | p56lck, LFA-1 and PI3K but not SHP-2 interact with GM1- or GM3-enriched microdomains in a CD4-p56lck association-dependent manner. | 2007 | Biochem. J. | pmid:17123354 |
| Larsson EA et al. | Synthesis of reference standards to enable single cell metabolomic studies of tetramethylrhodamine-labeled ganglioside GM1. | 2007 | Carbohydr. Res. | pmid:17069778 |
| Wang P et al. | GM3 signals regulating TNF-alpha expression are mediated by Rictor and Arhgdib in mouse melanoma B16 cells. | 2007 | Oncology | pmid:18523362 |
| Wang Q et al. | Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell. | 2007 | Bioorg. Med. Chem. | pmid:17892942 |
| Crawley AC and Walkley SU | Developmental analysis of CNS pathology in the lysosomal storage disease alpha-mannosidosis. | 2007 | J. Neuropathol. Exp. Neurol. | pmid:17882013 |
| Azuma Y et al. | Enhanced expression of membrane-associated sialidase Neu3 decreases GD3 and increases GM3 on the surface of Jurkat cells during etoposide-induced apoptosis. | 2007 | Biol. Pharm. Bull. | pmid:17827720 |
| Sega M et al. | Short-range structure of a GM3 ganglioside membrane: comparison between experimental WAXS and computer simulation results. | 2007 | J Phys Chem B | pmid:17718468 |
| Noguchi M et al. | GM3 synthase gene is a novel biomarker for histological classification and drug sensitivity against epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. | 2007 | Cancer Sci. | pmid:17711504 |
| Toma L et al. | Synthesis, conformational studies, binding assessment and liposome insertion of a thioether-bridged mimetic of the antigen GM3 ganglioside lactone. | 2007 | Chembiochem | pmid:17705308 |
| Kabayama K et al. | Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17699617 |
| Gracheva EV et al. | Activation of ganglioside GM3 biosynthesis in human monocyte/macrophages during culturing in vitro. | 2007 | Biochemistry Mosc. | pmid:17680770 |
| Murozuka Y et al. | Lyso-GM3, its dimer, and multimer: their synthesis, and their effect on epidermal growth factor-induced receptor tyrosine kinase. | 2007 | Glycoconj. J. | pmid:17638075 |
| Hidari KI et al. | Binding kinetics of influenza viruses to sialic acid-containing carbohydrates. | 2007 | Glycoconj. J. | pmid:17624609 |
| Milani S et al. | Ganglioside GM(3) is stably associated to tyrosine-phosphorylated ErbB2/EGFR receptor complexes and EGFR monomers, but not to ErbB2. | 2007 | Biochim. Biophys. Acta | pmid:17521961 |
| Azuma Y et al. | Recombinant human hexamer-dominant IgM monoclonal antibody to ganglioside GM3 for treatment of melanoma. | 2007 | Clin. Cancer Res. | pmid:17473208 |
| Inokuchi J | Insulin resistance as a membrane microdomain disorder. | 2007 | Yakugaku Zasshi | pmid:17409686 |
| Wang P et al. | Positive regulation of tumor necrosis factor-alpha by ganglioside GM3 through Akt in mouse melanoma B16 cells. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17367758 |
| Caines ME et al. | Structural and mechanistic analyses of endo-glycoceramidase II, a membrane-associated family 5 glycosidase in the Apo and GM3 ganglioside-bound forms. | 2007 | J. Biol. Chem. | pmid:17329247 |
| RodrÃguez M et al. | Insights into the immunogenetic basis of two ganglioside-associated idiotypic networks. | 2007 | Immunobiology | pmid:17270710 |
| Venier C et al. | Innate-immunity cytokines induced by very small size proteoliposomes, a Neisseria-derived immunological adjuvant. | 2007 | Clin. Exp. Immunol. | pmid:17223981 |
| Nuzzi PA et al. | Asymmetric localization of calpain 2 during neutrophil chemotaxis. | 2007 | Mol. Biol. Cell | pmid:17192410 |
| Ryazantsev S et al. | Lysosomal accumulation of SCMAS (subunit c of mitochondrial ATP synthase) in neurons of the mouse model of mucopolysaccharidosis III B. | 2007 | Mol. Genet. Metab. | pmid:17185018 |
| Grauby-Heywang C and Turlet JM | Study of the cholesterol-GM3 ganglioside interaction by surface pressure measurements and fluorescence microscopy. | 2007 | Colloids Surf B Biointerfaces | pmid:17137761 |
| Wang XQ et al. | Suppression of epidermal growth factor receptor signaling by protein kinase C-alpha activation requires CD82, caveolin-1, and ganglioside. | 2007 | Cancer Res. | pmid:17942932 |
| Uemura S et al. | Cell growth arrest by sialic acid clusters in ganglioside GM3 mimetic polymers. | 2007 | Glycobiology | pmid:17317719 |
| Fujita A et al. | Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling. | 2007 | Mol. Biol. Cell | pmid:17392511 |
| López-Requena A et al. | Gangliosides, Ab1 and Ab2 antibodies III. The idiotype of anti-ganglioside mAb P3 is immunogenic in a T cell-dependent manner. | 2007 | Mol. Immunol. | pmid:17316805 |
| Martinez Z et al. | GM1 specifically interacts with alpha-synuclein and inhibits fibrillation. | 2007 | Biochemistry | pmid:17253773 |
| López-Requena A et al. | Gangliosides, Ab1 and Ab2 antibodies II. Light versus heavy chain: An idiotype-anti-idiotype case study. | 2007 | Mol. Immunol. | pmid:16620986 |
| Jacques S et al. | Chemoenzymatic synthesis of GM3 and GM2 gangliosides containing a truncated ceramide functionalized for glycoconjugate synthesis and solid phase applications. | 2006 | Org. Biomol. Chem. | pmid:16358009 |
| Yoon SJ et al. | Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17142315 |
| Sørensen LK | A liquid chromatography/tandem mass spectrometric approach for the determination of gangliosides GD3 and GM3 in bovine milk and infant formulae. | 2006 | Rapid Commun. Mass Spectrom. | pmid:17094170 |
| Andrade CM et al. | Gangliosides of the stroma layer participate in the interferon-gamma receptor-dependent controls of myelopoiesis. | 2006 | Biochim. Biophys. Acta | pmid:16962370 |
| Pantzar M et al. | Binding of Haemophilus ducreyi to carbohydrate receptors is mediated by the 58.5-kDa GroEL heat shock protein. | 2006 | Microbes Infect. | pmid:16880000 |
| Terabayashi T et al. | Inhibition of influenza-virus-induced cytopathy by sialylglycoconjugates. | 2006 | Carbohydr. Res. | pmid:16854400 |
| Wang Z et al. | Roles for UDP-GlcNAc 2-epimerase/ManNAc 6-kinase outside of sialic acid biosynthesis: modulation of sialyltransferase and BiP expression, GM3 and GD3 biosynthesis, proliferation, and apoptosis, and ERK1/2 phosphorylation. | 2006 | J. Biol. Chem. | pmid:16847058 |
| Wang XQ et al. | Ganglioside GM3 promotes carcinoma cell proliferation via urokinase plasminogen activator-induced extracellular signal-regulated kinase-independent p70S6 kinase signaling. | 2006 | J. Invest. Dermatol. | pmid:16826166 |
| Chigorno V et al. | Efflux of sphingolipids metabolically labeled with [1-3H]sphingosine, L-[3- 3H]serine and [9,10- 3H]palmitic acid from normal cells in culture. | 2006 | Glycoconj. J. | pmid:16691499 |
| Bennaceur K et al. | Melanoma-derived gangliosides impair migratory and antigen-presenting function of human epidermal Langerhans cells and induce their apoptosis. | 2006 | Int. Immunol. | pmid:16675488 |
| Valaperta R et al. | Plasma membrane production of ceramide from ganglioside GM3 in human fibroblasts. | 2006 | FASEB J. | pmid:16645048 |
| Sohn H et al. | Ganglioside GM3 is involved in neuronal cell death. | 2006 | FASEB J. | pmid:16636105 |
| Wang XQ and Paller AS | Lipid rafts: membrane triage centers. | 2006 | J. Invest. Dermatol. | pmid:16619013 |
| Choi HJ et al. | Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway. | 2006 | Glycobiology | pmid:16574813 |
| Chefalo P et al. | Efficient metabolic engineering of GM3 on tumor cells by N-phenylacetyl-D-mannosamine. | 2006 | Biochemistry | pmid:16533056 |
| Hashiramoto A et al. | Ganglioside GM3 promotes cell migration by regulating MAPK and c-Fos/AP-1. | 2006 | Oncogene | pmid:16491123 |
| Oliva JP et al. | Clinical evidences of GM3 (NeuGc) ganglioside expression in human breast cancer using the 14F7 monoclonal antibody labelled with (99m)Tc. | 2006 | Breast Cancer Res. Treat. | pmid:16322892 |
| Grauby-Heywang C and Turlet JM | Behavior of GM3 ganglioside in lipid monolayers mimicking rafts or fluid phase in membranes. | 2006 | Chem. Phys. Lipids | pmid:16310758 |
| de Leòn J et al. | Role of tumour-associated N-glycolylated variant of GM3 ganglioside in cancer progression: effect over CD4 expression on T cells. | 2006 | Cancer Immunol. Immunother. | pmid:16208470 |
| Rich JR et al. | Chemical and chemoenzymatic synthesis of S-linked ganglioside analogues and their protein conjugates for use as immunogens. | 2006 | Chemistry | pmid:16196067 |
| Sottocornola E et al. | Role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells. | 2006 | FEBS J. | pmid:16623716 |
| Noguchi M et al. | Endogenously produced ganglioside GM3 endows etoposide and doxorubicin resistance by up-regulating Bcl-2 expression in 3LL Lewis lung carcinoma cells. | 2006 | Glycobiology | pmid:16571667 |
| Odintsova E et al. | Gangliosides play an important role in the organization of CD82-enriched microdomains. | 2006 | Biochem. J. | pmid:16859490 |
| Rojas-Garcia R et al. | A novel antiganglioside specificity against terminal NeuNAc(alfa 2-3)Gal in acute bulbar palsy. | 2006 | J. Neuroimmunol. | pmid:16707165 |
| Yoon SJ et al. | Interaction of N-linked glycans, having multivalent GlcNAc termini, with GM3 ganglioside. | 2006 | Glycoconj. J. | pmid:17115280 |
| Thiesen PH et al. | Glycolipids from a colloid chemical point of view. | 2006 | J. Biotechnol. | pmid:16707183 |
| Fort S et al. | Biosynthesis of conjugatable saccharidic moieties of GM2 and GM3 gangliosides by engineered E. coli. | 2005 | Chem. Commun. (Camb.) | pmid:15900325 |
| Hernández AM et al. | Generation of anti-Neu-glycolyl-ganglioside antibodies by immunization with an anti-idiotype monoclonal antibody: A self versus non-self-matter. | 2005 | Immunobiology | pmid:16076030 |
| Kwak DH et al. | Differential expression patterns of gangliosides in the ischemic cerebral cortex produced by middle cerebral artery occlusion. | 2005 | Mol. Cells | pmid:16404149 |
| Masson E et al. | a-Series gangliosides mediate the effects of advanced glycation end products on pericyte and mesangial cell proliferation: a common mediator for retinal and renal microangiopathy? | 2005 | Diabetes | pmid:15616032 |
| Park EJ et al. | Diet-induced changes in membrane gangliosides in rat intestinal mucosa, plasma and brain. | 2005 | J. Pediatr. Gastroenterol. Nutr. | pmid:15795600 |
| Wang XQ et al. | Gangliosides inhibit urokinase-type plasminogen activator (uPA)-dependent squamous carcinoma cell migration by preventing uPA receptor/alphabeta integrin/epidermal growth factor receptor interactions. | 2005 | J. Invest. Dermatol. | pmid:15816844 |
| Ju EJ et al. | Pathophysiological implication of ganglioside GM3 in early mouse embryonic development through apoptosis. | 2005 | Arch. Pharm. Res. | pmid:16212238 |
| Mise K et al. | Involvement of ganglioside GM3 in G(2)/M cell cycle arrest of human monocytic cells induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin. | 2005 | Infect. Immun. | pmid:16040998 |
| Hikita T et al. | De-N-acetyllactotriaosylceramide as a novel cationic glycosphingolipid of bovine brain white matter: isolation and characterization. | 2005 | Biochemistry | pmid:15996110 |
| Dreisewerd K et al. | Analysis of gangliosides directly from thin-layer chromatography plates by infrared matrix-assisted laser desorption/ionization orthogonal time-of-flight mass spectrometry with a glycerol matrix. | 2005 | Anal. Chem. | pmid:15987115 |
| Brønnum H et al. | Milk-derived GM(3) and GD(3) differentially inhibit dendritic cell maturation and effector functionalities. | 2005 | Scand. J. Immunol. | pmid:15963050 |
| Garofalo T et al. | Lipid microdomains contribute to apoptosis-associated modifications of mitochondria in T cells. | 2005 | Cell Death Differ. | pmid:15947792 |
| Mitsuzuka K et al. | A specific microdomain ("glycosynapse 3") controls phenotypic conversion and reversion of bladder cancer cells through GM3-mediated interaction of alpha3beta1 integrin with CD9. | 2005 | J. Biol. Chem. | pmid:16103120 |
| Kwak DH et al. | Ganglioside GM3 inhibits the high glucose- and TGF-beta1-induced proliferation of rat glomerular mesangial cells. | 2005 | Life Sci. | pmid:15939439 |
| Walker SR et al. | Neuroblastoma-induced inhibition of dendritic cell IL-12 production via abrogation of CD40 expression. | 2005 | J. Pediatr. Surg. | pmid:15868592 |
| Fujimoto Y et al. | Ganglioside GM3 inhibits proliferation and invasion of glioma. | 2005 | J. Neurooncol. | pmid:15690123 |
| Kabayama K et al. | TNFalpha-induced insulin resistance in adipocytes as a membrane microdomain disorder: involvement of ganglioside GM3. | 2005 | Glycobiology | pmid:15306563 |
| Panasiewicz M et al. | HPLC-based procedure for the preparation of carbene-generating photoreactive GM3 and GM1 ganglioside derivatives radioiodinated to high specific radioactivity with chloramine T as an oxidant. | 2005 | Anal. Biochem. | pmid:15840512 |
| Toledo MS et al. | Effect of ganglioside and tetraspanins in microdomains on interaction of integrins with fibroblast growth factor receptor. | 2005 | J. Biol. Chem. | pmid:15710618 |
| Shimamoto S et al. | Changes in ganglioside content affect the binding of Clostridium perfringens epsilon-toxin to detergent-resistant membranes of Madin-Darby canine kidney cells. | 2005 | Microbiol. Immunol. | pmid:15781998 |
| Cressant A et al. | Improved behavior and neuropathology in the mouse model of Sanfilippo type IIIB disease after adeno-associated virus-mediated gene transfer in the striatum. | 2004 | J. Neurosci. | pmid:15537895 |
| MartÃn-Sosa S et al. | Lactational changes in the fatty acid composition of human milk gangliosides. | 2004 | Lipids | pmid:15134137 |
| Mattei V et al. | Prion protein is a component of the multimolecular signaling complex involved in T cell activation. | 2004 | FEBS Lett. | pmid:14987990 |
| Prendergast MM et al. | In vivo phase variation and serologic response to lipooligosaccharide of Campylobacter jejuni in experimental human infection. | 2004 | Infect. Immun. | pmid:14742536 |
| Rojas G et al. | Light-chain shuffling results in successful phage display selection of functional prokaryotic-expressed antibody fragments to N-glycolyl GM3 ganglioside. | 2004 | J. Immunol. Methods | pmid:15541278 |
| Miura Y et al. | Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside). | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15534203 |
| Simpson MA et al. | Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase. | 2004 | Nat. Genet. | pmid:15502825 |
| Sorice M et al. | Role of GM3-enriched microdomains in signal transduction regulation in T lymphocytes. | 2004 | Glycoconj. J. | pmid:14993837 |
| Krengel U et al. | Structure and molecular interactions of a unique antitumor antibody specific for N-glycolyl GM3. | 2004 | J. Biol. Chem. | pmid:14627696 |
| Irie RF et al. | Phase I pilot clinical trial of human IgM monoclonal antibody to ganglioside GM3 in patients with metastatic melanoma. | 2004 | Cancer Immunol. Immunother. | pmid:14564483 |
| Bode L et al. | human and bovine milk gangliosides differ in their fatty acid composition. | 2004 | J. Nutr. | pmid:15514268 |
G(M3) Ganglioside
G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.
Cross Reference
Introduction
To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with G(M3) Ganglioside?
G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with G(M3) Ganglioside
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with G(M3) Ganglioside?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with G(M3) Ganglioside?
There are no associated biomedical information in the current reference collection.