G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

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All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Chen XP et al. Ganglioside control over IL-4 priming and cytokine production in activated T cells. 2000 Cytokine pmid:10880242
Carr A et al. A mouse IgG1 monoclonal antibody specific for N-glycolyl GM3 ganglioside recognized breast and melanoma tumors. 2000 Hybridoma pmid:10952412
Ji MY et al. Developmental patterns of mST3GalV mRNA expression in the mouse: in situ hybridization using DIG-labeled RNA probes. 2000 Arch. Pharm. Res. pmid:11059835
Handa K et al. Analysis of glycolipid-dependent cell adhesion based on carbohydrate-carbohydrate interaction. 2000 Meth. Enzymol. pmid:11070893
Iwabuchi K et al. Separation of glycosphingolipid-enriched microdomains from caveolar membrane characterized by presence of caveolin. 2000 Meth. Enzymol. pmid:11070896
Chiavegatto S et al. A functional role for complex gangliosides: motor deficits in GM2/GD2 synthase knockout mice. 2000 Exp. Neurol. pmid:11085888
Duclos RI The total synthesis of ganglioside GM3. 2000 Carbohydr. Res. pmid:11093705
Kasuya MC et al. Azido glycoside primer: a versatile building block for the biocombinatorial synthesis of glycosphingolipid analogues. 2000 Carbohydr. Res. pmid:11125817
Wang Y et al. Mechanistic study of modulation of SR Ca2+-ATPpase activity by gangliosides GM1 and GM3 through some biophysical measurements. 1999 Glycoconj. J. pmid:11133018
Kawai H et al. Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures. 2001 J. Biol. Chem. pmid:11133999
van Meer G What sugar next? Dimerization of sphingolipid glycosyltransferases. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11171945
Giraudo CG et al. Physical and functional association of glycolipid N-acetyl-galactosaminyl and galactosyl transferases in the Golgi apparatus. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11172001
Fantini J et al. Role of glycosphingolipid microdomains in CD4-dependent HIV-1 fusion. Glycoconj. J. pmid:11201791
Inokuchi JI et al. Glycosphingolipid deficiency affects functional microdomain formation in Lewis lung carcinoma cells. Glycoconj. J. pmid:11201796
Sorice M et al. Association between GM3 and CD4-Ick complex in human peripheral blood lymphocytes. Glycoconj. J. pmid:11201797
Kopitz J et al. Desialylation of extracellular GD1a-neoganglioprotein suggests cell surface orientation of the plasma membrane-bound ganglioside sialidase activity in human neuroblastoma cells. 2001 FEBS Lett. pmid:11240133
Nakatsuji Y and Miller RH Selective cell-cycle arrest and induction of apoptosis in proliferating neural cells by ganglioside GM3. 2001 Exp. Neurol. pmid:11259117
Noll EN et al. GM3 as a novel growth regulator for human gliomas. 2001 Exp. Neurol. pmid:11259118
Tatsumi K et al. Enhanced expression of a-series gangliosides in fibroblasts of patients with peroxisome biogenesis disorders. 2001 Biochim. Biophys. Acta pmid:11278168
Aoyama K et al. Guillain-Barré syndrome complicated with hemolytic anemia in association with antiganglioside GM3 antibody. 2001 Am. J. Med. pmid:11286955