G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Murthy RV et al. Exploiting the lactose-GM3 interaction for drug delivery. 2015 ChemMedChem pmid:25801320
Sugawara Y et al. Clostridium botulinum type C hemagglutinin affects the morphology and viability of cultured mammalian cells via binding to the ganglioside GM3. 2015 FEBS J. pmid:26077172
Dodge JC et al. Glycosphingolipids are modulators of disease pathogenesis in amyotrophic lateral sclerosis. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:26056266
Vukovic I et al. The missing link - likely pathogenetic role of GM3 and other gangliosides in the development of diabetic nephropathy. 2015 Kidney Blood Press. Res. pmid:26043887
Zheng XJ et al. Improvement of the immune efficacy of carbohydrate vaccines by chemical modification on the GM3 antigen. 2015 Org. Biomol. Chem. pmid:25982227
Mozzi A et al. NEU3 activity enhances EGFR activation without affecting EGFR expression and acts on its sialylation levels. 2015 Glycobiology pmid:25922362
Randeria PS et al. siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25902507
Yu X et al. Dressing up Nanoparticles: A Membrane Wrap to Induce Formation of the Virological Synapse. 2015 ACS Nano pmid:25853367
DeMarco ML Molecular dynamics simulations of membrane- and protein-bound glycolipids using GLYCAM. 2015 Methods Mol. Biol. pmid:25753721
Yoshikawa M et al. Ganglioside GM3 is essential for the structural integrity and function of cochlear hair cells. 2015 Hum. Mol. Genet. pmid:25652401