| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gopalakrishna P et al. | Cholesterol alters the interaction of glycosphingolipid GM3 with alpha5beta1 integrin and increases integrin-mediated cell adhesion to fibronectin. | 2004 | Exp. Cell Res. | pmid:15383313 |
| Aoki H et al. | Inhibition of motility and invasiveness of renal cell carcinoma induced by short interfering RNA transfection of beta 1,4GalNAc transferase. | 2004 | FEBS Lett. | pmid:15178323 |
| Mattei V et al. | Prion protein is a component of the multimolecular signaling complex involved in T cell activation. | 2004 | FEBS Lett. | pmid:14987990 |
| Rawat SS et al. | Elevated expression of GM3 in receptor-bearing targets confers resistance to human immunodeficiency virus type 1 fusion. | 2004 | J. Virol. | pmid:15220409 |
| Toledo MS et al. | Cell growth regulation through GM3-enriched microdomain (glycosynapse) in human lung embryonal fibroblast WI38 and its oncogenic transformant VA13. | 2004 | J. Biol. Chem. | pmid:15143068 |
| Rho YI et al. | Mechanism for the negative regulation of cell proliferation by ganglioside GM3 in high glucose-treated glomerular mesangial cells. | 2004 | Life Sci. | pmid:15102521 |
| Inokuchi J et al. | Glycosphingolipids govern gene expression. | 2004 | Glycoconj. J. | pmid:15090730 |
| Kindzelskii AL et al. | Cutting edge: optical microspectrophotometry supports the existence of gel phase lipid rafts at the lamellipodium of neutrophils: apparent role in calcium signaling. | 2004 | J. Immunol. | pmid:15067042 |
| Kasuya MC et al. | Fluorous-tagged compound: a viable scaffold to prime oligosaccharide synthesis by cellular enzymes. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15033442 |
| Sorice M et al. | Role of GM3-enriched microdomains in signal transduction regulation in T lymphocytes. | 2004 | Glycoconj. J. | pmid:14993837 |
| Beermann C et al. | Chemical and enzymatic transacylation of amide-linked FA of buttermilk gangliosides. | 2003 | Lipids | pmid:14577665 |
| MartÃn MJ et al. | Enterotoxigenic Escherichia coli strains bind bovine milk gangliosides in a ceramide-dependent process. | 2003 | Lipids | pmid:14506839 |
| Rapoport E et al. | Ganglioside binding pattern of CD33-related siglecs. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12639556 |
| Wang XQ et al. | Ganglioside GM3 blocks the activation of epidermal growth factor receptor induced by integrin at specific tyrosine sites. | 2003 | J. Biol. Chem. | pmid:14512423 |
| Wang XQ et al. | Ganglioside GM3 inhibits matrix metalloproteinase-9 activation and disrupts its association with integrin. | 2003 | J. Biol. Chem. | pmid:12724312 |
| Péguet-Navarro J et al. | Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis. | 2003 | J. Immunol. | pmid:12646609 |
| Loberto N et al. | The adhesion protein TAG-1 has a ganglioside environment in the sphingolipid-enriched membrane domains of neuronal cells in culture. | 2003 | J. Neurochem. | pmid:12641744 |
| Sottocornola E et al. | GM3 content modulates the EGF-activated p185c-neu levels, but not those of the constitutively activated oncoprotein p185neu. | 2003 | Biochim. Biophys. Acta | pmid:14729068 |
| RodrÃguez M et al. | Generation and characterization of an anti-idiotype monoclonal antibody related to GM3(NeuGc) ganglioside. | 2003 | Hybrid. Hybridomics | pmid:14678648 |
| Hakomori S and Handa K | Interaction of glycosphingolipids with signal transducers and membrane proteins in glycosphingolipid-enriched microdomains. | 2003 | Meth. Enzymol. | pmid:14579576 |
| DÃaz A et al. | Immune responses in breast cancer patients immunized with an anti-idiotype antibody mimicking NeuGc-containing gangliosides. | 2003 | Clin. Immunol. | pmid:12763476 |
| Carr A et al. | Immunotherapy of advanced breast cancer with a heterophilic ganglioside (NeuGcGM3) cancer vaccine. | 2003 | J. Clin. Oncol. | pmid:12637465 |
| Matuoka S et al. | Phase behavior in multilamellar vesicles of DPPC containing ganglioside GM3 with a C18:1 sphingoid base and a 24:0 acyl chain (GM3(18,24)) observed by X-ray diffraction. | 2003 | Chem. Phys. Lipids | pmid:12637162 |
| Kwak DH et al. | Expressional changes of ganglioside GM3 during ovarian maturation and early embryonic development in db/db mice. | 2003 | Dev. Growth Differ. | pmid:12630950 |
| Yamashita T et al. | Enhanced insulin sensitivity in mice lacking ganglioside GM3. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12629211 |
| Kwak DH et al. | Decreases of ganglioside GM3 in streptozotocin-induced diabetic glomeruli of rats. | 2003 | Life Sci. | pmid:12597998 |
| Li W et al. | Identification of glycosphingolipid binding sites for SEF21-fimbriated Salmonella enterica serovar Enteritidis in chicken oviductal mucosa. | 2003 | Vet. Microbiol. | pmid:12591208 |
| Santacroce PV and Basu A | Probing specificity in carbohydrate-carbohydrate interactions with micelles and Langmuir monolayers. | 2003 | Angew. Chem. Int. Ed. Engl. | pmid:19757601 |
| Garofalo T et al. | Association of the death-inducing signaling complex with microdomains after triggering through CD95/Fas. Evidence for caspase-8-ganglioside interaction in T cells. | 2003 | J. Biol. Chem. | pmid:12499380 |
| Pender MP et al. | Increased circulating T cell reactivity to GM3 and GQ1b gangliosides in primary progressive multiple sclerosis. | 2003 | J Clin Neurosci | pmid:12464524 |
| Akiyoshi K et al. | Induction of neuron-like tubes and liposome networks by cooperative effect of gangliosides and phospholipids. | 2003 | FEBS Lett. | pmid:12527358 |
| Irvine AD et al. | A colorimetric bead-binding assay for detection of intermolecular interactions. | 2002 | Exp. Dermatol. | pmid:12366700 |
| Mehta RR et al. | In vitro transformation of human congenital naevus to malignant melanoma. | 2002 | Melanoma Res. | pmid:11828255 |
| Guerry P et al. | Phase variation of Campylobacter jejuni 81-176 lipooligosaccharide affects ganglioside mimicry and invasiveness in vitro. | 2002 | Infect. Immun. | pmid:11796612 |
| Kawakami Y et al. | Tetraspanin CD9 is a "proteolipid," and its interaction with alpha 3 integrin in microdomain is promoted by GM3 ganglioside, leading to inhibition of laminin-5-dependent cell motility. | 2002 | J. Biol. Chem. | pmid:12068006 |
| Markotić A et al. | Ganglioside expression in tissues of mice lacking beta2-microglobulin. | 2002 | Clin. Exp. Immunol. | pmid:11982587 |
| Miljan EA et al. | Interaction of the extracellular domain of the epidermal growth factor receptor with gangliosides. | 2002 | J. Biol. Chem. | pmid:11796728 |
| Gabri MR et al. | Role of cell surface GM3 ganglioside and sialic acid in the antitumor activity of a GM3-based vaccine in the murine B16 melanoma model. | 2002 | J. Cancer Res. Clin. Oncol. | pmid:12474053 |
| Cui ZC et al. | Effects of ganglioside GM3 on phospholipid turnover of human leukemic J6-2 cells. | 2002 | Neurochem. Res. | pmid:12374212 |
| Wang XQ et al. | Ganglioside induces caveolin-1 redistribution and interaction with the epidermal growth factor receptor. | 2002 | J. Biol. Chem. | pmid:12354760 |
| Aoyama Y | Experimental studies on the effects of the combined use of N-(4-hydroxyphenyl)retinamide (4-HPR) and tamoxifen (TAM) for estrogen receptor (ER)-negative breast cancer. | 2002 | Kurume Med J | pmid:12235869 |
| Hakomori S | Glycosylation defining cancer malignancy: new wine in an old bottle. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12149519 |
| Alves F et al. | Inhibition of EGF-mediated receptor activity and cell proliferation by HK1-ceramide, a stable analog of the ganglioside GM3-lactone. | 2002 | Glycobiology | pmid:12145192 |
| Bada A et al. | Toxicity of a GM3 cancer vaccine in Macaca fascicularis monkey: a 12-month study. | 2002 | Hum Exp Toxicol | pmid:12141397 |
| Saito M et al. | Molecular cloning of Chinese hamster ceramide glucosyltransferase and its enhanced expression in peroxisome-defective mutant Z65 cells. | 2002 | Arch. Biochem. Biophys. | pmid:12139966 |
| Watanabe R et al. | Ganglioside G(M3) overexpression induces apoptosis and reduces malignant potential in murine bladder cancer. | 2002 | Cancer Res. | pmid:12097299 |
| Garofalo T et al. | Ganglioside GM3 activates ERKs in human lymphocytic cells. | 2002 | J. Lipid Res. | pmid:12032173 |
| Inoue M et al. | Refractory skin injury in complex knock-out mice expressing only the GM3 ganglioside. | 2002 | J. Biol. Chem. | pmid:12023957 |
| Sonnenburg JL et al. | Characterization of the acid stability of glycosidically linked neuraminic acid: use in detecting de-N-acetyl-gangliosides in human melanoma. | 2002 | J. Biol. Chem. | pmid:11884388 |
| Yu S et al. | Binding of rainbow trout sperm to egg is mediated by strong carbohydrate-to-carbohydrate interaction between (KDN)GM3 (deaminated neuraminyl ganglioside) and Gg3-like epitope. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11880637 |
| Alfonso M et al. | An anti-idiotype vaccine elicits a specific response to N-glycolyl sialic acid residues of glycoconjugates in melanoma patients. | 2002 | J. Immunol. | pmid:11859147 |
| Garofalo T et al. | Association of GM3 with Zap-70 induced by T cell activation in plasma membrane microdomains: GM3 as a marker of microdomains in human lymphocytes. | 2002 | J. Biol. Chem. | pmid:11781312 |
| Sawada M et al. | Reduced sialidase expression in highly metastatic variants of mouse colon adenocarcinoma 26 and retardation of their metastatic ability by sialidase overexpression. | 2002 | Int. J. Cancer | pmid:11774262 |
| Tagami S et al. | Ganglioside GM3 participates in the pathological conditions of insulin resistance. | 2002 | J. Biol. Chem. | pmid:11707432 |
| Mirkin BL et al. | Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B. | 2002 | Cell Prolif. | pmid:11952645 |
| Schnaar RL et al. | Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides. | 2002 | Anal. Biochem. | pmid:11878808 |
| Ardail D et al. | Subcellular distribution and metabolic fate of exogenous ceramides taken up by HL-60 cells. | 2002 | Biochim. Biophys. Acta | pmid:12176398 |
| Kawatake S et al. | Isolation and structure of monomethylated GM3-type ganglioside molecular species from the starfish Luidia maculata. | 2002 | Chem. Pharm. Bull. | pmid:12372870 |
| Sciannamblo M et al. | Changes of the ganglioside pattern and content in human fibroblasts by high density cell population subculture progression. | 2002 | Glycoconj. J. | pmid:12815229 |
| Saito M and Sugiyama K | Gangliosides in rat kidney: composition, distribution, and developmental changes. | 2001 | Arch. Biochem. Biophys. | pmid:11360994 |
| Bussell K | Pole position. | 2001 | Nat. Rev. Mol. Cell Biol. | pmid:11575272 |
| Zuolo ML et al. | Identification of GM3 as a marker of therapy-resistant periradicular lesions. | 2001 | J Endod | pmid:11491632 |
| Gómez-Móuton C et al. | Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11493690 |
| Gouni-Berthold I et al. | Gangliosides GM1 and GM2 induce vascular smooth muscle cell proliferation via extracellular signal-regulated kinase 1/2 pathway. | 2001 | Hypertension | pmid:11711493 |
| Pierini LM and Maxfield FR | Flotillas of lipid rafts fore and aft. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11504934 |
| Giraudo CG et al. | Physical and functional association of glycolipid N-acetyl-galactosaminyl and galactosyl transferases in the Golgi apparatus. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11172001 |
| van Meer G | What sugar next? Dimerization of sphingolipid glycosyltransferases. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11171945 |
| Kawamura S et al. | Glycolipid composition in bladder tumor: a crucial role of GM3 ganglioside in tumor invasion. | 2001 | Int. J. Cancer | pmid:11745412 |
| Bassi R et al. | GM3 ganglioside inhibits endothelin-1-mediated signal transduction in C6 glioma cells. | 2001 | FEBS Lett. | pmid:11682066 |
| Perez A et al. | Immunogenetic analysis of variable regions encoding AB1 and gamma-type AB2 antibodies from the NeuGc-containing ganglioside family. | 2001 | Hybridoma | pmid:11604106 |
| Sorice M et al. | Evidence for cell surface association between CXCR4 and ganglioside GM3 after gp120 binding in SupT1 lymphoblastoid cells. | 2001 | FEBS Lett. | pmid:11591370 |
| Jung KY et al. | Differential distribution of ganglioside GM3 in seminiferous tubule and epididymis of adult rats. | 2001 | Arch. Pharm. Res. | pmid:11534772 |
| Valiente O et al. | Preparation of deacetyl-, lyso-, and deacetyl-lyso-GM(3) by selective alkaline hydrolysis of GM3 ganglioside. | 2001 | J. Lipid Res. | pmid:11483634 |
| Satoh M et al. | Enhanced GM3 expression, associated with decreased invasiveness, is induced by brefeldin A in bladder cancer cells. | 2001 | Int. J. Oncol. | pmid:11562747 |
| Zajicek HK et al. | Glycosphingolipids modulate renal phosphate transport in potassium deficiency. | 2001 | Kidney Int. | pmid:11473652 |
| Carr A et al. | A purified GM3 ganglioside conjugated vaccine induces specific, adjuvant-dependent and non-transient antitumour activity against B16 mouse melanoma in vitro and in vivo. | 2001 | Melanoma Res. | pmid:11468510 |
| Wang XQ et al. | Epidermal growth factor receptor glycosylation is required for ganglioside GM3 binding and GM3-mediated suppression [correction of suppresion] of activation. | 2001 | Glycobiology | pmid:11447130 |
| Chakraborty M and Chatterjee D | Coupling of nerve growth factor to its receptor: inhibition by anti-GM3 ganglioside antibody. | 2001 | Cell. Mol. Neurobiol. | pmid:11440194 |
| Ono M et al. | GM3 ganglioside inhibits CD9-facilitated haptotactic cell motility: coexpression of GM3 and CD9 is essential in the downregulation of tumor cell motility and malignancy. | 2001 | Biochemistry | pmid:11371204 |
| Bobryshev YV et al. | Phenotype determination of anti-GM3 positive cells in atherosclerotic lesions of the human aorta. Hypothetical role of ganglioside GM3 in foam cell formation. | 2001 | Biochim. Biophys. Acta | pmid:11341997 |
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G(M3) Ganglioside
G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.
Cross Reference
Introduction
To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with G(M3) Ganglioside?
G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with G(M3) Ganglioside
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with G(M3) Ganglioside?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with G(M3) Ganglioside?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with G(M3) Ganglioside?
There are no associated biomedical information in the current reference collection.