G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

Cross Reference

Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with G(M3) Ganglioside?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with G(M3) Ganglioside?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with G(M3) Ganglioside?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

Download all related citations
Per page 10 20 50 100 | Total 773
Authors Title Published Journal PubMed Link
Hashiramoto A et al. Ganglioside GM3 promotes cell migration by regulating MAPK and c-Fos/AP-1. 2006 Oncogene pmid:16491123
Suárez Pestana E et al. The transmembrane protein tyrosine phosphatase RPTPsigma modulates signaling of the epidermal growth factor receptor in A431 cells. 1999 Oncogene pmid:10435588
Bergner DW et al. Inhibition of rotavirus infectivity by a neoglycolipid receptor mimetic. 2011 Nutrients pmid:22254094
Geissler D et al. Composition and biogenesis of complex carbohydrates of ox adrenal chromaffin granules. 1977 Neuroscience pmid:593551
Asou H et al. Changes in ganglioside composition and morphological features during the development of cultured astrocytes from rat brain. 1989 Neurosci. Res. pmid:2725993
Heffer-Lauc M et al. Anti-GM3 (II3Neu5Ac-lactosylceramide) ganglioside antibody labels human fetal Purkinje neurons during the critical stage of cerebellar development. 1996 Neurosci. Lett. pmid:8858616
Akasako Y et al. Inhibition of ganglioside synthesis reduces the neuronal survival activity of astrocytes. 2011 Neurosci. Lett. pmid:21093540
Nishimura B et al. The influences of sphingolipid metabolites on gentamicin-induced hair cell loss of the rat cochlea. 2010 Neurosci. Lett. pmid:20709153
Oikawa N et al. Gangliosides determine the amyloid pathology of Alzheimer's disease. 2009 Neuroreport pmid:19590389
Guan F et al. Regulation of epidermal growth factor receptor through interaction of ganglioside GM3 with GlcNAc of N-linked glycan of the receptor: demonstration in ldlD cells. 2011 Neurochem. Res. pmid:21203834
Spessott W et al. Defective GM3 synthesis in Cog2 null mutant CHO cells associates to mislocalization of lactosylceramide sialyltransferase in the Golgi complex. 2010 Neurochem. Res. pmid:21080064
Maxzúd MK and Maccioni HJ Compartmental organization of the synthesis of GM3, GD3, and GM2 in golgi membranes from neural retina cells. 1997 Neurochem. Res. pmid:9130256
Maxzúd MK and Maccioni HJ Glucosylceramide synthesized in vitro from endogenous ceramide is uncoupled from synthesis of lactosylceramide in Golgi membranes from chicken embryo neural retina cells. 2000 Neurochem. Res. pmid:10685614
Essaka DC et al. Single cell ganglioside catabolism in primary cerebellar neurons and glia. 2012 Neurochem. Res. pmid:22407243
Cui ZC et al. Effects of ganglioside GM3 on phospholipid turnover of human leukemic J6-2 cells. 2002 Neurochem. Res. pmid:12374212
Dawson G et al. Abnormal gangliosides are localized in lipid rafts in Sanfilippo (MPS3a) mouse brain. 2012 Neurochem. Res. pmid:22484966
Zaprianova E et al. Serum ganglioside patterns in multiple sclerosis. 2001 Neurochem. Res. pmid:11478747
Bussell K Pole position. 2001 Nat. Rev. Mol. Cell Biol. pmid:11575272
Natoli TA et al. Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models. 2010 Nat. Med. pmid:20562878
Simpson MA et al. Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase. 2004 Nat. Genet. pmid:15502825