G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

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All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Yamamura S et al. A close association of GM3 with c-Src and Rho in GM3-enriched microdomains at the B16 melanoma cell surface membrane: a preliminary note. 1997 Biochem. Biophys. Res. Commun. pmid:9223455
Kato E et al. Interaction between ganglioside-containing liposome and rat T-lymphocyte: confocal fluorescence microscopic study. 1994 Biochem. Biophys. Res. Commun. pmid:7945325
Ladisch S et al. A chemically synthesized sialic acid-containing glycoconjugate, 2-(tetradecylhexadecyl)-O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-ga lacto-2-nonulopyranosylonic acid)-(2-->3)-O-beta-D-galactopyrannosyl-(1-->4)-beta-D- glucopyrannoside, is a potent inhibitor of cellular immune responses. 1994 Biochem. Biophys. Res. Commun. pmid:8093028
Kniep B et al. Association of the GPI-anchored leucocyte surface glycoproteins with ganglioside GM3. 1994 Biochem. Biophys. Res. Commun. pmid:7522441
Dumontet C et al. Kinetics and organ distribution of [14C]-sialic acid-GM3 and [3H]-sphingosine-GM1 after intravenous injection in rats. 1992 Biochem. Biophys. Res. Commun. pmid:1482356
Levery SB et al. A novel strategy for unambiguous determination of inner esterification sites of ganglioside lactones. 1989 Biochem. Biophys. Res. Commun. pmid:2757642
Swamy MJ and Sweeley CC On the metabolism of GM3 ganglioside in cultured human foreskin fibroblasts. 1989 Biochem. Biophys. Res. Commun. pmid:2764928
Saito M et al. An acidic glycosphingolipid, monosialo-ganglioside GM3, is a potent physiological inducer for monocytic differentiation of human promyelocytic leukemia cell line HL-60 cells. 1985 Biochem. Biophys. Res. Commun. pmid:3864442
Kazui A et al. Glycosylation affects translocation of integrin, Src, and caveolin into or out of GEM. 2000 Biochem. Biophys. Res. Commun. pmid:10873579
Kanda N Gangliosides GD1a and GM3 induce interleukin-10 production by human T cells. 1999 Biochem. Biophys. Res. Commun. pmid:10066419