G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Kang S et al. Altered levels of α-synuclein and sphingolipids in Batten disease lymphoblast cells. 2014 Gene pmid:24534465
Jaishree G and Sharmila DJ Molecular dynamics study of the conformations of glycosidic linkages in sialic acid modified ganglioside GM3 analogues. 2014 Glycoconj. J. pmid:24909815
Lukina E et al. Eliglustat, an investigational oral therapy for Gaucher disease type 1: Phase 2 trial results after 4 years of treatment. 2014 Blood Cells Mol. Dis. pmid:24835462
Chung TW et al. The ganglioside GM3 is associated with cisplatin-induced apoptosis in human colon cancer cells. 2014 PLoS ONE pmid:24829158
Alfonso S et al. A randomized, multicenter, placebo-controlled clinical trial of racotumomab-alum vaccine as switch maintenance therapy in advanced non-small cell lung cancer patients. 2014 Clin. Cancer Res. pmid:24788102
Huang Q et al. A new liquid chromatography/tandem mass spectrometry method for quantification of gangliosides in human plasma. 2014 Anal. Biochem. pmid:24680754
Lee H et al. Inhibition of GM3 synthase attenuates neuropathology of Niemann-Pick disease Type C. by affecting sphingolipid metabolism. 2014 Mol. Cells pmid:24599001
Qu H et al. Synthesis and cytotoxicity assay of four ganglioside GM3 analogues. 2014 Eur J Med Chem pmid:24534540
Inokuchi J GM3 and diabetes. 2014 Glycoconj. J. pmid:24399479
Wang XQ et al. Ganglioside GM3 depletion reverses impaired wound healing in diabetic mice by activating IGF-1 and insulin receptors. 2014 J. Invest. Dermatol. pmid:24326453