G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Hamasaki H et al. GT1b in human metastatic brain tumors: GT1b as a brain metastasis-associated ganglioside. 1999 Biochim. Biophys. Acta pmid:9931455
Zehavi U and Tuchinsky A Enzymic glycosphingolipid synthesis on polymer supports. III. Synthesis of GM3, its analog [NeuNAcalpha(2-3)Galbeta(1-4)Glcbeta(1-3)Cer] and their lyso-derivatives. 1998 Glycoconj. J. pmid:9881771
Garofalo T et al. A novel mechanism of CD4 down-modulation induced by monosialoganglioside GM3. Involvement of serine phosphorylation and protein kinase c delta translocation. 1998 J. Biol. Chem. pmid:9857052
Sadatipour BT et al. Increased circulating antiganglioside antibodies in primary and secondary progressive multiple sclerosis. 1998 Ann. Neurol. pmid:9851447
Misasi R et al. Colocalization and complex formation between prosaposin and monosialoganglioside GM3 in neural cells. 1998 J. Neurochem. pmid:9832129
Chigorno V et al. Human fibroblasts in culture metabolize differently exogenous G(M3) ganglioside species containing C18 and C20 sphingosine. 1998 Acta Biochim. Pol. pmid:9821869
Sietsma H et al. Inhibition of hemopoiesis in vitro by neuroblastoma-derived gangliosides. 1998 Cancer Res. pmid:9809988
Fantini J et al. HIV-1-induced perturbations of glycosphingolipid metabolism are cell-specific and can be detected at early stages of HIV-1 infection. 1998 J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. pmid:9803963
Ecsedy JA et al. Tumor-infiltrating macrophages influence the glycosphingolipid composition of murine brain tumors. 1998 J. Lipid Res. pmid:9799808
Kiddle GR and Homans SW Residual dipolar couplings as new conformational restraints in isotropically 13C-enriched oligosaccharides. 1998 FEBS Lett. pmid:9771907