| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Komura N et al. | Syntheses of Fluorescent Gangliosides for the Studies of Raft Domains. | 2017 | Meth. Enzymol. | pmid:28935104 |
| Dufresne M et al. | Multimodal detection of GM2 and GM3 lipid species in the brain of mucopolysaccharidosis type II mouse by serial imaging mass spectrometry and immunohistochemistry. | 2017 | Anal Bioanal Chem | pmid:27873002 |
| Suzuki KGN et al. | Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging. | 2017 | Biochim. Biophys. Acta | pmid:28734966 |
| Trilck M et al. | Diversity of glycosphingolipid GM2 and cholesterol accumulation in NPC1 patient-specific iPSC-derived neurons. | 2017 | Brain Res. | pmid:27923633 |
| Worstell NC et al. | Binding Cooperativity Matters: A GM1-Like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array. | 2016 | PLoS ONE | pmid:27070150 |
| Kohyama M et al. | In situ detection of GM1 and GM2 gangliosides using immunohistochemical and immunofluorescent techniques for auxiliary diagnosis of canine and feline gangliosidoses. | 2016 | BMC Vet. Res. | pmid:27036194 |
| Wolf H et al. | A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease. | 2016 | Dis Model Mech | pmid:27491075 |
| Jones PC and Irie RF | Therapeutic Strategies for Human IgM Antibodies Directed at Tumor-Associated Ganglioside Antigens: Discoveries Made During the Morton Era and Future Directions. | 2016 | Crit Rev Oncog | pmid:27481004 |
| Ishigaki H et al. | Childhood-Onset Multifocal Motor Neuropathy With Immunoglobulin M Antibodies to Gangliosides GM1 and GM2: AÂ Case Report and Review of the Literature. | 2016 | Pediatr. Neurol. | pmid:27400822 |
| Tanaka K et al. | Enhanced expression of unique gangliosides with GM2-determinant in human uterine cervical carcinoma-derived cell lines. | 2016 | Glycoconj. J. | pmid:27270764 |
| Karumuthil-Melethil S et al. | Novel Vector Design and Hexosaminidase Variant Enabling Self-Complementary Adeno-Associated Virus for the Treatment of Tay-Sachs Disease. | 2016 | Hum. Gene Ther. | pmid:27197548 |
| Kundu M et al. | Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathway. | 2016 | Biochim. Biophys. Acta | pmid:27066976 |
| Spagnoli C et al. | CMV-associated axonal sensory-motor Guillain-Barré syndrome in a child: Case report and review of the literature. | 2016 | Eur. J. Paediatr. Neurol. | pmid:26621312 |
| Yin Z et al. | Chemical Synthesis of GM2 Glycans, Bioconjugation with Bacteriophage Qβ, and the Induction of Anticancer Antibodies. | 2016 | Chembiochem | pmid:26538065 |
| Sikora J et al. | X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities. | 2016 | Dis Model Mech | pmid:26515654 |
| Grey M et al. | Acceleration of α-synuclein aggregation by exosomes. | 2015 | J. Biol. Chem. | pmid:25425650 |
| Mahata B et al. | GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway. | 2015 | PLoS ONE | pmid:26226135 |
| Anheuser S et al. | Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity. | 2015 | J. Lipid Res. | pmid:26175473 |
| Walia JS et al. | Long-term correction of Sandhoff disease following intravenous delivery of rAAV9 to mouse neonates. | 2015 | Mol. Ther. | pmid:25515709 |
| Li Q et al. | Therapeutic activity of glycoengineered anti-GM2 antibodies against malignant pleural mesothelioma. | 2015 | Cancer Sci. | pmid:25421609 |
Ganglioside GM2
Ganglioside GM2 is a lipid of Sphingolipids (SP) class. Ganglioside gm2 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Autoimmune Diseases, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating and Neuromuscular Diseases. The involved functions are known as Pressure- physical agent, Cytolysis, Inflammation, Complement-Dependent Cytotoxicity and conjugation. Ganglioside gm2 often locates in Membrane, Entire nervous system, Cell surface, Biopsy sample and Lipid Bilayers. The associated genes with Ganglioside GM2 are anti-IgM, Polypeptides, Transgenes, Alleles and Homologous Gene. The related lipids are Ganglioside GA2, QS 21, sulfate-3-glucuronyl paragloboside, Lipopolysaccharides and IV(4)-galactosyl-N-acetylganglioside GD1a. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GM2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GM2?
Ganglioside GM2 is suspected in Tay-Sachs Disease, Gangliosidoses GM2, Sandhoff Disease, Neuropathy, Cytomegalovirus Infections, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GM2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GM2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GM2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GM2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GM2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GM2?
Disease model
Disease model are used in the study 'Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.' (Ho CW et al., 2010) and Disease model are used in the study 'Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies.' (Tsuji D et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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