| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mardinoglu A et al. | Integration of clinical data with a genome-scale metabolic model of the human adipocyte. | 2013 | Mol. Syst. Biol. | pmid:23511207 |
| Sinici I et al. | In cellulo examination of a beta-alpha hybrid construct of beta-hexosaminidase A subunits, reported to interact with the GM2 activator protein and hydrolyze GM2 ganglioside. | 2013 | PLoS ONE | pmid:23483939 |
| Rupp A et al. | The effects of age and ganglioside composition on the rate of motor nerve terminal regeneration following antibody-mediated injury in mice. | 2013 | Synapse | pmid:23401234 |
| Milnik A et al. | Acute inflammatory neuropathy with monoclonal anti-GM2 IgM antibodies, IgM-κ paraprotein and additional autoimmune processes in association with a diffuse large B-cell non-Hodgkin's lymphoma. | 2013 | BMJ Case Rep | pmid:23341581 |
| Yamaguchi T et al. | Ganglioside-embedding small bicelles for probing membrane-landing processes of intrinsically disordered proteins. | 2013 | Chem. Commun. (Camb.) | pmid:23296043 |
| Sargeant TJ et al. | Characterization of inducible models of Tay-Sachs and related disease. | 2012 | PLoS Genet. | pmid:23028353 |
| Liu F et al. | Molecular and biochemical characterization of a novel β-N-acetyl-D-hexosaminidase with broad substrate-spectrum from the Aisan corn borer, Ostrinia furnacalis. | 2012 | Int. J. Biol. Sci. | pmid:22991497 |
| Kim CS et al. | Functional interaction analysis of GM1-related carbohydrates and Vibrio cholerae toxins using carbohydrate microarray. | 2012 | Anal. Chem. | pmid:22770420 |
| Hoshino T et al. | Simultaneous development of acute disseminated encephalomyelitis and Guillain-Barré syndrome associated with H1N1 09 influenza vaccination. | 2012 | Intern. Med. | pmid:22728497 |
| Pernber Z et al. | Altered distribution of the gangliosides GM1 and GM2 in Alzheimer's disease. | 2012 | Dement Geriatr Cogn Disord | pmid:22572791 |
| Wilkinson FL et al. | Neuropathology in mouse models of mucopolysaccharidosis type I, IIIA and IIIB. | 2012 | PLoS ONE | pmid:22558223 |
| Keilani S et al. | Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-β peptide. | 2012 | J. Neurosci. | pmid:22496568 |
| Dawson G et al. | Abnormal gangliosides are localized in lipid rafts in Sanfilippo (MPS3a) mouse brain. | 2012 | Neurochem. Res. | pmid:22484966 |
| Saito M et al. | Elevation of GM2 ganglioside during ethanol-induced apoptotic neurodegeneration in the developing mouse brain. | 2012 | J. Neurochem. | pmid:22372857 |
| Arthur JR et al. | Therapeutic effects of stem cells and substrate reduction in juvenile Sandhoff mice. | 2012 | Neurochem. Res. | pmid:22367451 |
| Nagahori N et al. | Use of carbohydrate-conjugated nanoparticles for an integrated approach to functional imaging of glycans and understanding of their molecular mechanisms. | 2012 | Curr Pharm Biotechnol | pmid:22039811 |
| Whitehead B et al. | Experiences of dying, death and bereavement in motor neurone disease: a qualitative study. | 2012 | Palliat Med | pmid:21712334 |
| Matsuoka K et al. | Thymic involution and corticosterone level in Sandhoff disease model mice: new aspects the pathogenesis of GM2 gangliosidosis. | 2011 | J. Inherit. Metab. Dis. | pmid:21598013 |
| Smyth KA et al. | Acquired infantile abducens palsy associated with anti-GM2 antibodies. | 2011 | Pediatr. Neurol. | pmid:21555058 |
| Tetala KK et al. | Selective depletion of neuropathy-related antibodies from human serum by monolithic affinity columns containing ganglioside mimics. | 2011 | J. Med. Chem. | pmid:21488704 |
Ganglioside GM2
Ganglioside GM2 is a lipid of Sphingolipids (SP) class. Ganglioside gm2 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Autoimmune Diseases, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating and Neuromuscular Diseases. The involved functions are known as Pressure- physical agent, Cytolysis, Inflammation, Complement-Dependent Cytotoxicity and conjugation. Ganglioside gm2 often locates in Membrane, Entire nervous system, Cell surface, Biopsy sample and Lipid Bilayers. The associated genes with Ganglioside GM2 are anti-IgM, Polypeptides, Transgenes, Alleles and Homologous Gene. The related lipids are Ganglioside GA2, QS 21, sulfate-3-glucuronyl paragloboside, Lipopolysaccharides and IV(4)-galactosyl-N-acetylganglioside GD1a. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GM2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GM2?
Ganglioside GM2 is suspected in Tay-Sachs Disease, Gangliosidoses GM2, Sandhoff Disease, Neuropathy, Cytomegalovirus Infections, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GM2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GM2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GM2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GM2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GM2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GM2?
Disease model
Disease model are used in the study 'Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.' (Ho CW et al., 2010) and Disease model are used in the study 'Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies.' (Tsuji D et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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