| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ang CW et al. | Guillain-Barré syndrome- and Miller Fisher syndrome-associated Campylobacter jejuni lipopolysaccharides induce anti-GM1 and anti-GQ1b Antibodies in rabbits. | 2001 | Infect. Immun. | pmid:11254608 |
| Parajuli P et al. | Humanized anti-ganglioside GM2 antibody is effective to induce antibody-dependent cell-mediated cytotoxicity in mononuclear cells from lung cancer patients. | 2001 | Cancer Lett. | pmid:11275367 |
| Werth N et al. | Degradation of membrane-bound ganglioside GM2 by beta -hexosaminidase A. Stimulation by GM2 activator protein and lysosomal lipids. | 2001 | J. Biol. Chem. | pmid:11278374 |
| Kirkwood JM et al. | High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. | 2001 | J. Clin. Oncol. | pmid:11331315 |
| Yoshida S et al. | Ganglioside G(D2) in small cell lung cancer cell lines: enhancement of cell proliferation and mediation of apoptosis. | 2001 | Cancer Res. | pmid:11358851 |
| Saito M and Sugiyama K | Gangliosides in rat kidney: composition, distribution, and developmental changes. | 2001 | Arch. Biochem. Biophys. | pmid:11360994 |
| Nakamura K et al. | Dissection and optimization of immune effector functions of humanized anti-ganglioside GM2 monoclonal antibody. | 2000 | Mol. Immunol. | pmid:11399321 |
| Op Den Velde W and Hooghwinkel GJ | The brain ganglioside pattern in presenile and senile dementia. | 1975 | J Am Geriatr Soc | pmid:1141629 |
| Hedberg KM et al. | Monoclonal anti-GD3 antibodies selectively inhibit the proliferation of human malignant glioma cells in vitro. | 2000 | Glycoconj. J. | pmid:11425192 |
| Hanibuchi M et al. | Immunological circumvention of multiple organ metastases of multidrug resistant human small cell lung cancer cells by mouse-human chimeric anti-ganglioside GM2 antibody KM966. | 2000 | Clin. Exp. Metastasis | pmid:11467766 |
Ganglioside GM2
Ganglioside GM2 is a lipid of Sphingolipids (SP) class. Ganglioside gm2 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Autoimmune Diseases, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating and Neuromuscular Diseases. The involved functions are known as Pressure- physical agent, Cytolysis, Inflammation, Complement-Dependent Cytotoxicity and conjugation. Ganglioside gm2 often locates in Membrane, Entire nervous system, Cell surface, Biopsy sample and Lipid Bilayers. The associated genes with Ganglioside GM2 are anti-IgM, Polypeptides, Transgenes, Alleles and Homologous Gene. The related lipids are Ganglioside GA2, QS 21, sulfate-3-glucuronyl paragloboside, Lipopolysaccharides and IV(4)-galactosyl-N-acetylganglioside GD1a. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GM2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GM2?
Ganglioside GM2 is suspected in Tay-Sachs Disease, Gangliosidoses GM2, Sandhoff Disease, Neuropathy, Cytomegalovirus Infections, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GM2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GM2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GM2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GM2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GM2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GM2?
Disease model
Disease model are used in the study 'Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.' (Ho CW et al., 2010) and Disease model are used in the study 'Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies.' (Tsuji D et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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