| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gu J et al. | Simultaneous quantification of GM1 and GM2 gangliosides by isotope dilution tandem mass spectrometry. | 2008 | Clin. Biochem. | pmid:18241673 |
| Baek RC et al. | N-butyldeoxygalactonojirimycin reduces brain ganglioside and GM2 content in neonatal Sandhoff disease mice. | 2008 | Neurochem. Int. | pmid:18207611 |
| Li YT et al. | Effect of structural modifications of ganglioside GM2 on intra-molecular carbohydrate-to-carbohydrate interaction and enzymatic susceptibility. | 2008 | Biochim. Biophys. Acta | pmid:17967427 |
| Nobile-Orazio E et al. | How useful are anti-neural IgM antibodies in the diagnosis of chronic immune-mediated neuropathies? | 2008 | J. Neurol. Sci. | pmid:17915254 |
| Aguilar RP et al. | Renal gangliosides are involved in lead intoxication. | 2008 | J Appl Toxicol | pmid:17503479 |
| Larsson EA et al. | Synthesis of reference standards to enable single cell metabolomic studies of tetramethylrhodamine-labeled ganglioside GM1. | 2007 | Carbohydr. Res. | pmid:17069778 |
| Gavella M et al. | Antioxidant properties of ganglioside micelles. | 2007 | Free Radic. Res. | pmid:17886036 |
| Alvarez-Rueda N et al. | Binding activities and antitumor properties of a new mouse/human chimeric antibody specific for GD2 ganglioside antigen. | 2007 | Clin. Cancer Res. | pmid:17875797 |
| Raval G et al. | TNF-alpha induction of GM2 expression on renal cell carcinomas promotes T cell dysfunction. | 2007 | J. Immunol. | pmid:17475896 |
| López-Requena A et al. | Gangliosides, Ab1 and Ab2 antibodies III. The idiotype of anti-ganglioside mAb P3 is immunogenic in a T cell-dependent manner. | 2007 | Mol. Immunol. | pmid:17316805 |
| Martinez Z et al. | GM1 specifically interacts with alpha-synuclein and inhibits fibrillation. | 2007 | Biochemistry | pmid:17253773 |
| Todeschini AR et al. | Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse. | 2007 | J. Biol. Chem. | pmid:17215249 |
| Kawashima I et al. | Cytochemical analysis of storage materials in cultured skin fibroblasts from patients with I-cell disease. | 2007 | Clin. Chim. Acta | pmid:17204262 |
| Hasegawa D et al. | Clinical and molecular analysis of GM2 gangliosidosis in two apparent littermate kittens of the Japanese domestic cat. | 2007 | J. Feline Med. Surg. | pmid:17198760 |
| Tsuji D et al. | Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies. | 2007 | Clin. Chim. Acta | pmid:17196574 |
| Zhao Y et al. | Endowing self-binding feature restores the activities of a loss-of-function chimerized anti-GM2 antibody. | 2007 | Cancer Immunol. Immunother. | pmid:16896968 |
| López-Requena A et al. | Gangliosides, Ab1 and Ab2 antibodies II. Light versus heavy chain: An idiotype-anti-idiotype case study. | 2007 | Mol. Immunol. | pmid:16620986 |
| Fuse T et al. | Synthesis and enzymatic susceptibility of a series of novel GM2 analogs. | 2006 | Glycoconj. J. | pmid:16897176 |
| Itakura T et al. | Inefficiency in GM2 ganglioside elimination by human lysosomal beta-hexosaminidase beta-subunit gene transfer to fibroblastic cell line derived from Sandhoff disease model mice. | 2006 | Biol. Pharm. Bull. | pmid:16880605 |
| Crawley AC et al. | Characterization of a C57BL/6 congenic mouse strain of mucopolysaccharidosis type IIIA. | 2006 | Brain Res. | pmid:16828069 |
Ganglioside GM2
Ganglioside GM2 is a lipid of Sphingolipids (SP) class. Ganglioside gm2 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Autoimmune Diseases, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating and Neuromuscular Diseases. The involved functions are known as Pressure- physical agent, Cytolysis, Inflammation, Complement-Dependent Cytotoxicity and conjugation. Ganglioside gm2 often locates in Membrane, Entire nervous system, Cell surface, Biopsy sample and Lipid Bilayers. The associated genes with Ganglioside GM2 are anti-IgM, Polypeptides, Transgenes, Alleles and Homologous Gene. The related lipids are Ganglioside GA2, QS 21, sulfate-3-glucuronyl paragloboside, Lipopolysaccharides and IV(4)-galactosyl-N-acetylganglioside GD1a. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GM2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GM2?
Ganglioside GM2 is suspected in Tay-Sachs Disease, Gangliosidoses GM2, Sandhoff Disease, Neuropathy, Cytomegalovirus Infections, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GM2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GM2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GM2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GM2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GM2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GM2?
Disease model
Disease model are used in the study 'Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.' (Ho CW et al., 2010) and Disease model are used in the study 'Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies.' (Tsuji D et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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