| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Retter MW et al. | Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts. | 2005 | Cancer Res. | pmid:16024647 |
| Blixt O et al. | Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides GD3, GT3, GM2, GD2, GT2, GM1, and GD1a. | 2005 | Carbohydr. Res. | pmid:16005859 |
| Arfi A et al. | Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. | 2005 | Neurobiol. Dis. | pmid:15953731 |
| Livingston PO et al. | Selection of GM2, fucosyl GM1, globo H and polysialic acid as targets on small cell lung cancers for antibody mediated immunotherapy. | 2005 | Cancer Immunol. Immunother. | pmid:15926079 |
| Fort S et al. | Biosynthesis of conjugatable saccharidic moieties of GM2 and GM3 gangliosides by engineered E. coli. | 2005 | Chem. Commun. (Camb.) | pmid:15900325 |
| Gieselmann V | What can cell biology tell us about heterogeneity in lysosomal storage diseases? | 2005 | Acta Paediatr Suppl | pmid:15895717 |
| Tsuji D et al. | Specific induction of macrophage inflammatory protein 1-alpha in glial cells of Sandhoff disease model mice associated with accumulation of N-acetylhexosaminyl glycoconjugates. | 2005 | J. Neurochem. | pmid:15748167 |
| Santafé MM et al. | Changes in the neuromuscular synapse induced by an antibody against gangliosides. | 2005 | Ann. Neurol. | pmid:15732093 |
| Kyrkanides S et al. | beta-hexosaminidase lentiviral vectors: transfer into the CNS via systemic administration. | 2005 | Brain Res. Mol. Brain Res. | pmid:15710246 |
| Hernández AM et al. | Generation of anti-Neu-glycolyl-ganglioside antibodies by immunization with an anti-idiotype monoclonal antibody: A self versus non-self-matter. | 2005 | Immunobiology | pmid:16076030 |
| Ando T et al. | Facile method for the preparation of lyso-GM1 and lyso-GM2. | 2005 | J Chromatogr A | pmid:16010718 |
| Masson E et al. | Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: implication of gangliosides. | 2005 | Biochem. J. | pmid:15654767 |
| Moran AP et al. | Antibodies induced by ganglioside-mimicking Campylobacter jejuni lipooligosaccharides recognise epitopes at the nodes of Ranvier. | 2005 | J. Neuroimmunol. | pmid:15993494 |
| Usuki S et al. | AIDP and CIDP having specific antibodies to the carbohydrate epitope (-NeuAcalpha2-8NeuAcalpha2-3Galbeta1-4Glc-) of gangliosides. | 2005 | J. Neurol. Sci. | pmid:15850580 |
| Yamato O et al. | GM2-gangliosidosis variant 0 (Sandhoff-like disease) in a family of Japanese domestic cats. | 2004 | Vet. Rec. | pmid:15623087 |
| Cressant A et al. | Improved behavior and neuropathology in the mouse model of Sanfilippo type IIIB disease after adeno-associated virus-mediated gene transfer in the striatum. | 2004 | J. Neurosci. | pmid:15537895 |
| Kunishige M et al. | Isolated cranial neuropathy associated with anti-glycolipid antibodies. | 2004 | J. Neurol. Sci. | pmid:15465085 |
| Batuwangala T et al. | The crystal structure of human CD1b with a bound bacterial glycolipid. | 2004 | J. Immunol. | pmid:14764708 |
| Wendeler M et al. | Photoaffinity labelling of the human GM2-activator protein. Mechanistic insight into ganglioside GM2 degradation. | 2004 | Eur. J. Biochem. | pmid:14728689 |
| Yamaguchi A et al. | Possible role of autoantibodies in the pathophysiology of GM2 gangliosidoses. | 2004 | J. Clin. Invest. | pmid:14722612 |
Ganglioside GM2
Ganglioside GM2 is a lipid of Sphingolipids (SP) class. Ganglioside gm2 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Autoimmune Diseases, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating and Neuromuscular Diseases. The involved functions are known as Pressure- physical agent, Cytolysis, Inflammation, Complement-Dependent Cytotoxicity and conjugation. Ganglioside gm2 often locates in Membrane, Entire nervous system, Cell surface, Biopsy sample and Lipid Bilayers. The associated genes with Ganglioside GM2 are anti-IgM, Polypeptides, Transgenes, Alleles and Homologous Gene. The related lipids are Ganglioside GA2, QS 21, sulfate-3-glucuronyl paragloboside, Lipopolysaccharides and IV(4)-galactosyl-N-acetylganglioside GD1a. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GM2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GM2?
Ganglioside GM2 is suspected in Tay-Sachs Disease, Gangliosidoses GM2, Sandhoff Disease, Neuropathy, Cytomegalovirus Infections, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GM2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GM2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GM2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GM2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GM2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GM2?
Disease model
Disease model are used in the study 'Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.' (Ho CW et al., 2010) and Disease model are used in the study 'Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies.' (Tsuji D et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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