| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gaucher Disease | D005776 | 13 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Total
4
Ganglioside GI
Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GI, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GI?
Ganglioside GI is suspected in Neuropathy, Neuritis, Motor, Cholera, Gangliosidosis GM1, Virus Diseases, Neuritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ganglioside GI
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GI
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GI?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ganglioside GI?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GI?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GI?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ganglioside GI?
Knock-out
Knock-out are used in the study 'GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.' (Tessitore A et al., 2004) and Knock-out are used in the study 'GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.' (Hadaczek P et al., 2015).
Transgenic Model
Transgenic Model are used in the study 'Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.' (Di Pardo A et al., 2012).
Disease model
Disease model are used in the study 'Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action.' (Kreutz F et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ganglioside GI
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lopez PH et al. | Normal human plasma contains antibodies that specifically block neuropathy-associated human anti-GM1 IgG-antibodies. | 2000 | J. Neuroimmunol. | pmid:10742560 |
| Yoshino H et al. | IgG antiganglioside antibodies in Guillain-Barré syndrome with bulbar palsy. | 2000 | J. Neuroimmunol. | pmid:10742563 |
| Palestini P et al. | Tubulin anchoring to glycolipid-enriched, detergent-resistant domains of the neuronal plasma membrane. | 2000 | J. Biol. Chem. | pmid:10744673 |
| Ang CW et al. | Cross-reactive antibodies against GM2 and CMV-infected fibroblasts in Guillain-Barré syndrome. | 2000 | Neurology | pmid:10751257 |
| Kanda T et al. | Glycosphingolipid antibodies and blood-nerve barrier in autoimmune demyelinative neuropathy. | 2000 | Neurology | pmid:10751258 |
| Pope-Coleman A et al. | Effects of GM1 ganglioside treatment on pre- and postsynaptic dopaminergic markers in the striatum of parkinsonian monkeys. | 2000 | Synapse | pmid:10767059 |
| Saito M and Sugiyama K | A distinct ganglioside composition of rat pancreatic islets. | 2000 | Arch. Biochem. Biophys. | pmid:10775425 |
| Rottenberg ME et al. | Regulation and role of IFN-gamma in the innate resistance to infection with Chlamydia pneumoniae. | 2000 | J. Immunol. | pmid:10779789 |
| Kenworthy AK et al. | High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranes. | 2000 | Mol. Biol. Cell | pmid:10793141 |
| Azulay JP et al. | [Lower motor neuron disease and signs of dysimmunity]. | 2000 | Rev. Neurol. (Paris) | pmid:10795014 |
| Candelise L and Ciccone A | Gangliosides for acute ischaemic stroke. | 2000 | Cochrane Database Syst Rev | pmid:10796297 |
| Molander M et al. | Immunostaining of ganglioside GD1b, GD3 and GM1 in rat cerebellum: cellular layer and cell type specific associations. | 2000 | J. Neurosci. Res. | pmid:10797556 |
| Bhattacharya SK and Danishefsky SJ | A total synthesis of the methyl glycoside of ganglioside GM(1). | 2000 | J. Org. Chem. | pmid:10813908 |
| Brodsky VY et al. | Ganglioside-mediated metabolic synchronization of protein synthesis activity in cultured hepatocytes. | 2000 | Cell Biol. Int. | pmid:10816322 |
| Galbete JL et al. | Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway. | 2000 | Biochem. J. | pmid:10816423 |
| Picking WD | The use of fluorescence resonance energy transfer to detect conformational changes in protein toxins. | 2000 | Methods Mol. Biol. | pmid:10820720 |
| Odaka M et al. | Antibodies to GM1(NeuGc) in Guillain-Barré syndrome after ganglioside therapy. | 2000 | J. Neurol. Sci. | pmid:10831769 |
| Kornberg AJ | Anti-GM1 ganglioside antibodies: their role in the diagnosis and pathogenesis of immune-mediated motor neuropathies. | 2000 | J Clin Neurosci | pmid:10833614 |
| McCombe PA et al. | Results of testing for anti-GM1 antibodies. | 2000 | J Clin Neurosci | pmid:10833617 |
| Colella R et al. | GM1 enhances the association of neuron-specific MAP2 with actin in MAP2-transfected 3T3 cells. | 2000 | Brain Res. Dev. Brain Res. | pmid:10837887 |