| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Gaucher Disease | D005776 | 13 associated lipids |
Total
4
Ganglioside GI
Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GI, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GI?
Ganglioside GI is suspected in Neuropathy, Neuritis, Motor, Cholera, Gangliosidosis GM1, Virus Diseases, Neuritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ganglioside GI
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GI
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GI?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Ganglioside GI?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ganglioside GI?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Ganglioside GI?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ganglioside GI?
Knock-out
Knock-out are used in the study 'GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.' (Tessitore A et al., 2004) and Knock-out are used in the study 'GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.' (Hadaczek P et al., 2015).
Transgenic Model
Transgenic Model are used in the study 'Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.' (Di Pardo A et al., 2012).
Disease model
Disease model are used in the study 'Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action.' (Kreutz F et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Ganglioside GI
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Puddu P et al. | IL-12 induces IFN-gamma expression and secretion in mouse peritoneal macrophages. | 1997 | J. Immunol. | pmid:9317148 |
| Ilangumaran S et al. | Distinct interactions among GPI-anchored, transmembrane and membrane associated intracellular proteins, and sphingolipids in lymphocyte and endothelial cell plasma membranes. | 1997 | Biochim. Biophys. Acta | pmid:9315619 |
| Irie S et al. | Relationships between anti-ganglioside antibodies and clinical characteristics of Guillain-Barré syndrome. | 1997 | Intern. Med. | pmid:9313102 |
| Miyazaki H et al. | Expression cloning of rat cDNA encoding UDP-galactose:GD2 beta1,3-galactosyltransferase that determines the expression of GD1b/GM1/GA1. | 1997 | J. Biol. Chem. | pmid:9312075 |
| Wirguin I et al. | Induction of anti-GM1 ganglioside antibodies by Campylobacter jejuni lipopolysaccharides. | 1997 | J. Neuroimmunol. | pmid:9307238 |
| Attarian S et al. | [Guillain-Barré syndrome of axonal type, Campylobacter jejuni infection and anti-ganglioside GM1 antibodies]. | 1997 | Rev. Neurol. (Paris) | pmid:9296136 |
| Baumgartner WA et al. | Pathophysiology of cerebral injury and future management. | J Card Surg | pmid:9271760 | |
| Fuentes R et al. | Ganglioside expression in lung cancer cell lines. | 1997 | Lung Cancer | pmid:9268945 |
| Arnulphi C et al. | Ganglioside hydration study by 2H-NMR: dependence on temperature and water/lipid ratio. | 1997 | J. Lipid Res. | pmid:9254066 |
| Vogelsberg V et al. | Cholinergic deficits in aged rat spinal cord: restoration by GM1 ganglioside. | 1997 | Brain Res. | pmid:9252023 |
| Schmitt M et al. | Involvement of T-cell subsets and natural killer (NK) cells in the growth suppression of murine fibrosarcoma cells transfected with interleukin-12 (IL-12) genes. | 1997 | Int. J. Cancer | pmid:9247296 |
| Tanaka Y et al. | Gangliosides enhance KCl-induced Ca2+ influx and acetylcholine release in brain synaptosomes. | 1997 | Neuroreport | pmid:9243612 |
| Merritt EA et al. | Structural studies of receptor binding by cholera toxin mutants. | 1997 | Protein Sci. | pmid:9232653 |
| Ferraretto A et al. | Lipid domains in the membrane: thermotropic properties of sphingomyelin vesicles containing GM1 ganglioside and cholesterol. | 1997 | Biochemistry | pmid:9230056 |
| McCann JA et al. | Conformational changes in cholera toxin B subunit-ganglioside GM1 complexes are elicited by environmental pH and evoke changes in membrane structure. | 1997 | Biochemistry | pmid:9230049 |
| Chaouat G et al. | Immune suppression and Th1/Th2 balance in pregnancy revisited: a (very) personal tribute to Tom Wegmann. | 1997 | Am. J. Reprod. Immunol. | pmid:9228297 |
| Sorice M et al. | Evidence for the existence of ganglioside molecules in the antigen of Entamoeba histolytica. | 1996 | Parasite Immunol. | pmid:9223167 |
| Liljeqvist S et al. | Surface display of the cholera toxin B subunit on Staphylococcus xylosus and Staphylococcus carnosus. | 1997 | Appl. Environ. Microbiol. | pmid:9212399 |
| Velasco I and Tapia R | Ruthenium red neurotoxicity and interaction with gangliosides in primary cortical cultures. | 1997 | J. Neurosci. Res. | pmid:9211991 |
| Park HJ et al. | Conformational study of asialo-GM1 (GA1) ganglioside. | 1997 | Biopolymers | pmid:9209156 |