| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Gaucher Disease | D005776 | 13 associated lipids |
Total
4
Ganglioside GI
Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GI, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GI?
Ganglioside GI is suspected in Neuropathy, Neuritis, Motor, Cholera, Gangliosidosis GM1, Virus Diseases, Neuritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ganglioside GI
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GI
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GI?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ganglioside GI?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GI?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GI?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ganglioside GI?
Knock-out
Knock-out are used in the study 'GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.' (Tessitore A et al., 2004) and Knock-out are used in the study 'GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.' (Hadaczek P et al., 2015).
Transgenic Model
Transgenic Model are used in the study 'Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.' (Di Pardo A et al., 2012).
Disease model
Disease model are used in the study 'Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action.' (Kreutz F et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ganglioside GI
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bergh ML et al. | Specificity of porcine liver gal beta (1 leads to 3)galnac-r alpha(2 leads to 3) sialyltransferase sialylation of mucin-type acceptors and ganglioside GM1 in vitro. | 1981 | Biochim. Biophys. Acta | pmid:7284398 |
| Leon A et al. | Activation of (Na+, K+)-ATPase by nanomolar concentrations of GM1 ganglioside. | 1981 | J. Neurochem. | pmid:6267200 |
| Habu S et al. | In vivo effects of anti-asialo GM1. I. Reduction of NK activity and enhancement of transplanted tumor growth in nude mice. | 1981 | J. Immunol. | pmid:7240748 |
| Wiederschain GYa EM et al. | Specificity patterns of different types of human fucosidase. Recognition of a certain region of the pyranose ring in sugars by the enzymes. | 1981 | Biochim. Biophys. Acta | pmid:6789883 |
| Corti M et al. | GM1-ganglioside-Triton X-100 mixed micelles: changes of micellar properties studied by laser-light scattering and enzymatic methods. | 1981 | Chem. Phys. Lipids | pmid:7237653 |
| Kobayashi T and Suzuki K | Chronic GM1 gangliosidosis presenting as dystonia: II. Biochemical studies. | 1981 | Ann. Neurol. | pmid:6791575 |
| Goldman JE et al. | Chronic GM1 gangliosidosis presenting as dystonia: I. Clinical and pathological features. | 1981 | Ann. Neurol. | pmid:6791574 |
| Karpiak SE et al. | An immunological model of epilepsy: seizures induced by antibodies to GM1 ganglioside. | 1981 | Epilepsia | pmid:7472306 |
| Hinz HJ et al. | Influence of gangliosides GM1 and GD1a on structural and thermotropic properties of sonicated small 1,2-dipalmitoyl-L-alpha-phosphatidylcholine vesicles. | 1981 | Biochim. Biophys. Acta | pmid:6894700 |
| Tomasi M and Montecucco C | Lipid insertion of cholera toxin after binding to GM1-containing liposomes. | 1981 | J. Biol. Chem. | pmid:7287761 |
| Umesaki Y et al. | Presence of asialo GM1 and glucosylceramide in the intestinal mucosa of mice and induction of fucosyl asialo GM1 by conventionalization of germ-free mice. | 1981 | J. Biochem. | pmid:7334007 |
| Nygren H and Stenberg M | Electrophoresis of ligands over a surface coated with a binding receptor. A novel methodological principle for electroimmunoassays. | 1981 | FEBS Lett. | pmid:7319043 |
| Suzuki A and Yamakawa T | The different distribution of asialo GM1 and Forssman antigen in the small intestine of mouse demonstrated by immunofluorescence staining. | 1981 | J. Biochem. | pmid:6175621 |
| Slomiany BL et al. | Characterization of the sulfated monosialosyltriglycosylceramide from bovine gastric mucosa. | 1981 | Eur. J. Biochem. | pmid:7308206 |
| Craig JP et al. | Production of cholera-like enterotoxin by a Vibrio cholerae non-O1 strain isolated from the environment. | 1981 | Infect. Immun. | pmid:7298194 |
| Coulon-Morelec MJ and Buc-Caron MH | Lipid patterns of embryonal carcinoma cell lines and their derivatives: changes with differentiation. | 1981 | Dev. Biol. | pmid:7239013 |
| Matsumoto M et al. | Further characterization of the structure of GM1b ganglioside from rat ascites hepatoma. | 1981 | J. Biol. Chem. | pmid:7287705 |
| Shen BW et al. | Glycosphingolipid-high density lipoprotein 3 interactions. II. Characterization of the glycosphingolipid component of modified high density lipoprotein. | 1981 | J. Biol. Chem. | pmid:7287704 |
| Critchley DR et al. | Interaction of cholera toxin with rat intestinal brush border membranes. Relative roles of gangliosides and galactoproteins as toxin receptors. | 1981 | J. Biol. Chem. | pmid:7263681 |
| Ohkura T et al. | Urinary oligosaccharides of GM1-gangliosidosis. Structures of oligosaccharides excreted in the urine of type 1 but not in the urine of type 2 patients. | 1981 | J. Biol. Chem. | pmid:6790542 |