| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Gaucher Disease | D005776 | 13 associated lipids |
Total
4
Ganglioside GI
Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GI, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GI?
Ganglioside GI is suspected in Neuropathy, Neuritis, Motor, Cholera, Gangliosidosis GM1, Virus Diseases, Neuritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ganglioside GI
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GI
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GI?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ganglioside GI?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ganglioside GI?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GI?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ganglioside GI?
Knock-out
Knock-out are used in the study 'GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.' (Tessitore A et al., 2004) and Knock-out are used in the study 'GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.' (Hadaczek P et al., 2015).
Transgenic Model
Transgenic Model are used in the study 'Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.' (Di Pardo A et al., 2012).
Disease model
Disease model are used in the study 'Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action.' (Kreutz F et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ganglioside GI
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Godshall CJ et al. | Natural killer cells participate in bacterial clearance during septic peritonitis through interactions with macrophages. | 2003 | Shock | pmid:12578123 |
| Apostolski S and Latov N | Clinical syndromes associated with anti-GM1 antibodies. | 1993 | Semin Neurol | pmid:8272597 |
| Nagale SV and Bosch EP | Multifocal motor neuropathy with conduction block: current issues in diagnosis and treatment. | 2003 | Semin Neurol | pmid:14722828 |
| Aykutlu E et al. | No association of anti-GM1 and anti-GAD antibodies with juvenile myoclonic epilepsy: a pilot study. | 2005 | Seizure | pmid:15927491 |
| Umesaki Y et al. | Interactions between epithelial cells and bacteria, normal and pathogenic. | 1997 | Science | pmid:9139662 |
| Read DH et al. | Neuronal-visceral GM1 gangliosidosis in a dog with beta-galactosidase deficiency. | 1976 | Science | pmid:824730 |
| Schneider JS et al. | Recovery from experimental parkinsonism in primates with GM1 ganglioside treatment. | 1992 | Science | pmid:1350379 |
| Guan JL | Cell biology. Integrins, rafts, Rac, and Rho. | 2004 | Science | pmid:14764856 |
| Palazzo AF et al. | Localized stabilization of microtubules by integrin- and FAK-facilitated Rho signaling. | 2004 | Science | pmid:14764879 |
| del Pozo MA et al. | Integrins regulate Rac targeting by internalization of membrane domains. | 2004 | Science | pmid:14764880 |
| Freed EO | Virology. Rafting with Ebola. | 2002 | Science | pmid:11951027 |
| Spiegel S et al. | Direct evidence that endogenous GM1 ganglioside can mediate thymocyte proliferation. | 1985 | Science | pmid:2999979 |
| Hwang J et al. | Nanoscale complexity of phospholipid monolayers investigated by near-field scanning optical microscopy. | 1995 | Science | pmid:7570018 |
| Ribi HO et al. | Three-dimensional structure of cholera toxin penetrating a lipid membrane. | 1988 | Science | pmid:3344432 |
| Alroy J et al. | Neurovisceral and skeletal GM1-gangliosidosis in dogs with beta-galactosidase deficiency. | 1985 | Science | pmid:3925555 |
| Sabel BA et al. | GM1 ganglioside treatment facilitates behavioral recovery from bilateral brain damage. | 1984 | Science | pmid:6740316 |
| Richards JM et al. | Rectal insemination modifies immune responses in rabbits. | 1984 | Science | pmid:6608789 |
| Viola A et al. | T lymphocyte costimulation mediated by reorganization of membrane microdomains. | 1999 | Science | pmid:9924026 |
| Ryu YS et al. | Continuity of Monolayer-Bilayer Junctions for Localization of Lipid Raft Microdomains in Model Membranes. | 2016 | Sci Rep | pmid:27230411 |
| Eich C et al. | Changes in membrane sphingolipid composition modulate dynamics and adhesion of integrin nanoclusters. | 2016 | Sci Rep | pmid:26869100 |
| Lardone RD et al. | Individual Restriction Of Fine Specificity Variability In Anti-GM1 IgG Antibodies Associated With Guillain-Barré Syndrome. | 2016 | Sci Rep | pmid:26818965 |
| Takahashi R and Yuki N | Streptococcal IdeS: therapeutic potential for Guillain-Barré syndrome. | 2015 | Sci Rep | pmid:26194472 |
| Hata R et al. | Suppressed rate of carcinogenesis and decreases in tumour volume and lung metastasis in CXCL14/BRAK transgenic mice. | 2015 | Sci Rep | pmid:25765541 |
| Hamorsky KT et al. | N-glycosylation of cholera toxin B subunit in Nicotiana benthamiana: impacts on host stress response, production yield and vaccine potential. | 2015 | Sci Rep | pmid:25614217 |
| Evangelisti E et al. | Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases. | 2016 | Sci Rep | pmid:27619987 |
| Hao C et al. | Interaction between ganglioside G(M1) and diosgenin in langmuir monolayers at the air/water interface. | Scanning | pmid:23553978 | |
| Bromander AK et al. | Cholera toxin enhances alloantigen presentation by cultured intestinal epithelial cells. | 1993 | Scand. J. Immunol. | pmid:8469928 |
| Eren E et al. | Location of major histocompatibility complex class II molecules in rafts on dendritic cells enhances the efficiency of T-cell activation and proliferation. | 2006 | Scand. J. Immunol. | pmid:16398696 |
| Palmieri G et al. | TNF impairs in vivo and in vitro natural killer (NK) susceptibility of B16 melanoma cells. | 1992 | Scand. J. Immunol. | pmid:1535986 |
| Müller C et al. | Characterization of autoantibodies to natural killer cells in HIV-infected patients. | 1996 | Scand. J. Immunol. | pmid:8633218 |
| Asea A et al. | Histaminergic regulation of natural killer cell-mediated clearance of tumour cells in mice. | 1996 | Scand. J. Immunol. | pmid:8560202 |
| Allan JE and Doherty PC | Natural killer cells contribute to inflammation but do not appear to be essential for the induction of clinical lymphocytic choriomeningitis. | 1986 | Scand. J. Immunol. | pmid:3489282 |
| Ghayur T et al. | Induction, specificity and elimination of asialo-GM1+ graft-versus-host effector cells of donor origin. | 1991 | Scand. J. Immunol. | pmid:1833814 |
| MacDonald GC and Gartner JG | Natural killer (NK) cell activity in mice with acute graft-versus-host reactions: characterization of a Thy-1+ NK-like cell with a broadened spectrum of lytic activity in the spleen and lymph nodes. | 1991 | Scand. J. Immunol. | pmid:1709518 |
| Sihvola M | Lymphokine-activated killer cells in mouse bone marrow chimaeras. The relationship to natural killer cells and to alloreactive cytotoxic T cells. | 1985 | Scand. J. Immunol. | pmid:2867599 |
| Somasundaram R et al. | Limitations of the severe combined immunodeficiency (SCID) mouse model for study of human B-cell responses. | 1995 | Scand. J. Immunol. | pmid:7899826 |
| Wilson AD et al. | Whole cholera toxin and B subunit act synergistically as an adjuvant for the mucosal immune response of mice to keyhole limpet haemocyanin. | 1990 | Scand. J. Immunol. | pmid:2333468 |
| Hurme M et al. | Highly increased natural killer cell number and lytic activity in the murine peripheral blood and lungs after interferon induction in vivo. | 1984 | Scand. J. Immunol. | pmid:6209790 |
| Beaumont TJ et al. | Comparative analysis of cell surface markers on murine NK cells and CTL target-effector conjugates. | 1982 | Scand. J. Immunol. | pmid:6127796 |
| Owman T et al. | Radiographic skeletal changes in juvenile GM1-gangliosidosis. | 1980 | Rofo | pmid:6450132 |
| Ogawa G et al. | [Case of pure motor Guillain-Barré syndrome with motor conduction block and anti-GM1/GalNAc-GD1a antibody]. | 2009 | Rinsho Shinkeigaku | pmid:19827599 |
| Koike Y et al. | [A case of progressive encephalomyelitis with rigidity and myoclonus associated with anti-GAD, anti-glycine receptor and anti-GM1 antibodies]. | 2015 | Rinsho Shinkeigaku | pmid:25746075 |
| Arai M and Kusunoki S | [A case of multifocal motor neuropathy with IgM lambda anti-GM1 antibody and IgM kappa paraprotein reacting exclusively with GM2]. | Rinsho Shinkeigaku | pmid:19348179 | |
| Lievens I et al. | [Multifocal motor neuropathy: a retrospective study of sensory nerve conduction velocities in long-term follow-up of 21 patients]. | 2009 | Rev. Neurol. (Paris) | pmid:19118851 |
| Lefèvre C et al. | [Acute motor axon neuropathy, subtype of Guillain-Barre syndrome]. | 2002 | Rev. Neurol. (Paris) | pmid:12072835 |
| Attarian S et al. | [Guillain-Barré syndrome of axonal type, Campylobacter jejuni infection and anti-ganglioside GM1 antibodies]. | 1997 | Rev. Neurol. (Paris) | pmid:9296136 |
| Coste S et al. | [Acute polyradiculoneuropathy after Chlamydia pneumoniae infection]. | 2002 | Rev. Neurol. (Paris) | pmid:11976599 |
| Le Forestier N and Bouche P | [Motor conduction block]. | 2000 | Rev. Neurol. (Paris) | pmid:10891806 |
| Azulay JP et al. | [Lower motor neuron disease and signs of dysimmunity]. | 2000 | Rev. Neurol. (Paris) | pmid:10795014 |
| BadÃa Picazo MC et al. | [Hyperreflexia in a patient with Guillain Barre syndrome]. | Rev Neurol | pmid:15098195 |