| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Gaucher Disease | D005776 | 13 associated lipids |
Total
4
Ganglioside GI
Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GI, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GI?
Ganglioside GI is suspected in Neuropathy, Neuritis, Motor, Cholera, Gangliosidosis GM1, Virus Diseases, Neuritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ganglioside GI
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GI
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GI?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ganglioside GI?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ganglioside GI?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GI?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ganglioside GI?
Knock-out
Knock-out are used in the study 'GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.' (Tessitore A et al., 2004) and Knock-out are used in the study 'GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.' (Hadaczek P et al., 2015).
Transgenic Model
Transgenic Model are used in the study 'Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.' (Di Pardo A et al., 2012).
Disease model
Disease model are used in the study 'Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action.' (Kreutz F et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ganglioside GI
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mori K et al. | Formation of GM1 ganglioside clusters on the lipid membrane containing sphingomyeline and cholesterol. | 2012 | J Phys Chem B | pmid:22494278 |
| Rondelli V et al. | Ganglioside GM1 forces the redistribution of cholesterol in a biomimetic membrane. | 2012 | Biochim. Biophys. Acta | pmid:22828449 |
| Lucki NC and Sewer MB | Nuclear sphingolipid metabolism. | 2012 | Annu. Rev. Physiol. | pmid:21888508 |
| Yamagata S et al. | Non-genomic inhibitory effect of glucocorticoids on activated peripheral blood basophils through suppression of lipid raft formation. | 2012 | Clin. Exp. Immunol. | pmid:22943204 |
| Röckendorf N et al. | Molecular evolution of peptide ligands with custom-tailored characteristics for targeting of glycostructures. | 2012 | PLoS Comput. Biol. | pmid:23271960 |
| Ryu JS et al. | Ganglioside GM1 influences the proliferation rate of mouse induced pluripotent stem cells. | 2012 | BMB Rep | pmid:23261057 |
| Jobling MG et al. | A single native ganglioside GM1-binding site is sufficient for cholera toxin to bind to cells and complete the intoxication pathway. | 2012 | MBio | pmid:23111873 |
| Chang JC and Rosenthal SJ | Visualization of lipid raft membrane compartmentalization in living RN46A neuronal cells using single quantum dot tracking. | 2012 | ACS Chem Neurosci | pmid:23077717 |
| Gudejko HF et al. | Polar expansion during cytokinesis. | 2012 | Cytoskeleton (Hoboken) | pmid:23027735 |
| Chinnapen DJ et al. | Lipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1. | 2012 | Dev. Cell | pmid:22975326 |
| Wittenberg NJ et al. | High-density arrays of submicron spherical supported lipid bilayers. | 2012 | Anal. Chem. | pmid:22967217 |
| Lee SH et al. | Real-time full-spectral imaging and affinity measurements from 50 microfluidic channels using nanohole surface plasmon resonance. | 2012 | Lab Chip | pmid:22895607 |
| Oda M et al. | Clostridium perfringens alpha-toxin recognizes the GM1a-TrkA complex. | 2012 | J. Biol. Chem. | pmid:22847002 |
| Kabaso D et al. | The transport along membrane nanotubes driven by the spontaneous curvature of membrane components. | 2012 | Bioelectrochemistry | pmid:22502994 |
| Mauri L et al. | Anti-GM1/GD1a complex antibodies in GBS sera specifically recognize the hybrid dimer GM1-GD1a. | 2012 | Glycobiology | pmid:21921061 |
| Ohto U et al. | Crystal structure of human β-galactosidase: structural basis of Gm1 gangliosidosis and morquio B diseases. | 2012 | J. Biol. Chem. | pmid:22128166 |
| Damjanovich L et al. | Crohn's disease alters MHC-rafts in CD4+ T-cells. | 2012 | Cytometry A | pmid:22128034 |
| Willison HJ | The translation of the pathological findings described in humans to experimental models of acute motor axonal neuropathy. | 2012 | J. Peripher. Nerv. Syst. | pmid:23279424 |
| Bibolini MJ et al. | The hybrid between the ABC domains of synapsin and the B subunit of Escherichia coli heat-labile toxin ameliorates experimental autoimmune encephalomyelitis. | 2012 | Cell. Immunol. | pmid:23261829 |
| Miyazaki Y et al. | Interaction of antimicrobial peptide magainin 2 with gangliosides as a target for human cell binding. | 2012 | Biochemistry | pmid:23194027 |
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| Brambilla D et al. | P-glycoprotein binds to ezrin at amino acid residues 149-242 in the FERM domain and plays a key role in the multidrug resistance of human osteosarcoma. | 2012 | Int. J. Cancer | pmid:21780101 |
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| Ledeen RW et al. | Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1 [corrected]. | 2012 | Ann. N. Y. Acad. Sci. | pmid:22524425 |
| Kim JK et al. | Acute pure motor demyelinating neuropathy with hyperreflexia and anti-GalNAc-GD1a antibodies. | 2012 | Clin Neurol Neurosurg | pmid:22503060 |
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| Xue F et al. | Gene expression profile of Campylobacter jejuni-induced GBS in Bama miniature pigs. | 2012 | Cell Tissue Res. | pmid:22427118 |
| Chen XF et al. | The effect of monosialotetrahexosylganglioside (GM1) in prevention of oxaliplatin induced neurotoxicity: a retrospective study. | 2012 | Biomed. Pharmacother. | pmid:22397758 |
| Becker PM et al. | In vitro inhibition of ETEC K88 adhesion by pea hulls and of LT enterotoxin binding by faba bean hulls. | 2012 | J Anim Physiol Anim Nutr (Berl) | pmid:21929729 |
| Maurissen I et al. | First case of anti-ganglioside GM1-positive Guillain-Barré syndrome due to hepatitis E virus infection. | 2012 | Infection | pmid:21877179 |
| Israeli E et al. | Guillain-Barré syndrome--a classical autoimmune disease triggered by infection or vaccination. | 2012 | Clin Rev Allergy Immunol | pmid:20890797 |
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| Nishijima T et al. | Antiretroviral therapy for treatment-naïve chronic HIV-1 infection with an axonal variant of Guillain-Barré syndrome positive for anti-ganglioside antibody: a case report. | 2011 | Intern. Med. | pmid:22001481 |
| Chandrasekaran EV et al. | Mammalian sialyltransferase ST3Gal-II: its exchange sialylation catalytic properties allow labeling of sialyl residues in mucin-type sialylated glycoproteins and specific gangliosides. | 2011 | Biochemistry | pmid:21913655 |
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| Bond MR et al. | Metabolism of diazirine-modified N-acetylmannosamine analogues to photo-cross-linking sialosides. | 2011 | Bioconjug. Chem. | pmid:21838313 |
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| Huang SH et al. | Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3). | 2011 | J. Biol. Chem. | pmid:21693704 |
| Zhang YP et al. | GM1 improves neurofascin155 association with lipid rafts and prevents rat brain myelin injury after hypoxia-ischemia. | 2011 | Braz. J. Med. Biol. Res. | pmid:21670940 |
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