| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Gaucher Disease | D005776 | 13 associated lipids |
Total
4
Ganglioside GI
Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GI, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GI?
Ganglioside GI is suspected in Neuropathy, Neuritis, Motor, Cholera, Gangliosidosis GM1, Virus Diseases, Neuritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ganglioside GI
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GI
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GI?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ganglioside GI?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GI?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GI?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ganglioside GI?
Knock-out
Knock-out are used in the study 'GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.' (Tessitore A et al., 2004) and Knock-out are used in the study 'GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.' (Hadaczek P et al., 2015).
Transgenic Model
Transgenic Model are used in the study 'Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.' (Di Pardo A et al., 2012).
Disease model
Disease model are used in the study 'Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action.' (Kreutz F et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ganglioside GI
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bierfreund U et al. | Sphingolipid hydrolases and activator proteins. | 2000 | Meth. Enzymol. | pmid:10563332 |
| Knoll F et al. | Sphingolipid photoaffinity labels. | 2000 | Meth. Enzymol. | pmid:10563350 |
| Siagoside. GM1, Sygen. | 1999 | Drugs R D | pmid:10565981 | |
| Cox NR et al. | Alterations in the growth hormone/insulin-like growth factor I pathways in feline GM1 gangliosidosis. | 1999 | Endocrinology | pmid:10579334 |
| Cheng PC et al. | A role for lipid rafts in B cell antigen receptor signaling and antigen targeting. | 1999 | J. Exp. Med. | pmid:10587346 |
| Möbius W et al. | Gangliosides are transported from the plasma membrane to intralysosomal membranes as revealed by immuno-electron microscopy. | 1999 | Biosci. Rep. | pmid:10589996 |
| Mauri L et al. | A procedure for the preparation of GM3 ganglioside from GM1-lactone. | 1999 | Glycoconj. J. | pmid:10596894 |
| Holloway RG and Feasby TE | To test or not to test? That is the question. | 1999 | Neurology | pmid:10599756 |
| Ang CW et al. | Rapidly progressive, predominantly motor Guillain-Barré syndrome with anti-GalNAc-GD1a antibodies. | 1999 | Neurology | pmid:10599792 |
| Carpo M et al. | Marginally improved detection of GM1 antibodies by Covalink ELISA in multifocal motor neuropathy. | 1999 | Neurology | pmid:10599811 |
| Haque S et al. | Protection against lethal toxoplasmosis in mice by an avirulent strain of Toxoplasma gondii: stimulation of IFN-gamma and TNF-alpha response. | 1999 | Exp. Parasitol. | pmid:10600449 |
| Trambley J et al. | Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection. | 1999 | J. Clin. Invest. | pmid:10606625 |
| Matà S et al. | Multiple sclerosis is associated with enhanced B cell responses to the ganglioside GD1a. | 1999 | Mult. Scler. | pmid:10618693 |
| Chiaramonte MG et al. | CpG oligonucleotides can prophylactically immunize against Th2-mediated schistosome egg-induced pathology by an IL-12-independent mechanism. | 2000 | J. Immunol. | pmid:10623847 |
| Neisser A et al. | Ganglioside-induced antiganglioside antibodies from a neuropathy patient cross-react with lipopolysaccharides of Campylobacter jejuni associated with Guillain-Barré syndrome. | 2000 | J. Neuroimmunol. | pmid:10626671 |
| Tanigawa M et al. | Natural killer cells prevent direct anterior-to-posterior spread of herpes simplex virus type 1 in the eye. | 2000 | Invest. Ophthalmol. Vis. Sci. | pmid:10634612 |
| Dillon SR et al. | Annexin V binds to viable B cells and colocalizes with a marker of lipid rafts upon B cell receptor activation. | 2000 | J. Immunol. | pmid:10640746 |
| Fresta M and Puglisi G | Reduction of maturation phenomenon in cerebral ischemia with CDP-choline-loaded liposomes. | 1999 | Pharm. Res. | pmid:10644072 |
| Kuwabara S et al. | Isolated absence of F waves and proximal axonal dysfunction in Guillain-Barré syndrome with antiganglioside antibodies. | 2000 | J. Neurol. Neurosurg. Psychiatry | pmid:10644786 |
| Seidl EC | Promising pharmacological agents in the management of acute spinal cord injury. | 1999 | Crit Care Nurs Q | pmid:10646442 |