| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Gaucher Disease | D005776 | 13 associated lipids |
Total
4
Ganglioside GI
Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GI, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GI?
Ganglioside GI is suspected in Neuropathy, Neuritis, Motor, Cholera, Gangliosidosis GM1, Virus Diseases, Neuritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ganglioside GI
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GI
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GI?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ganglioside GI?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GI?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GI?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ganglioside GI?
Knock-out
Knock-out are used in the study 'GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.' (Tessitore A et al., 2004) and Knock-out are used in the study 'GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.' (Hadaczek P et al., 2015).
Transgenic Model
Transgenic Model are used in the study 'Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.' (Di Pardo A et al., 2012).
Disease model
Disease model are used in the study 'Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action.' (Kreutz F et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ganglioside GI
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rondelli V et al. | Neutrons for rafts, rafts for neutrons. | 2013 | Eur Phys J E Soft Matter | pmid:23852579 |
| Manna M and Mukhopadhyay C | Binding, conformational transition and dimerization of amyloid-β peptide on GM1-containing ternary membrane: insights from molecular dynamics simulation. | 2013 | PLoS ONE | pmid:23951128 |
| Rios FJ et al. | Uptake of oxLDL and IL-10 production by macrophages requires PAFR and CD36 recruitment into the same lipid rafts. | 2013 | PLoS ONE | pmid:24130805 |
| Rong X et al. | Ganglioside GM1 reduces white matter damage in neonatal rats. | 2013 | Acta Neurobiol Exp (Wars) | pmid:24129486 |
| Moeller S et al. | Lack of association between autism and anti-GM1 ganglioside antibody. | 2013 | Neurology | pmid:24068789 |
| Pellistri F et al. | Different ataxin-3 amyloid aggregates induce intracellular Ca(2+) deregulation by different mechanisms in cerebellar granule cells. | 2013 | Biochim. Biophys. Acta | pmid:24035922 |
| Saslowsky DE et al. | Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain. | 2013 | J. Biol. Chem. | pmid:23884419 |
| Itokazu Y et al. | Effects of amyloid β-peptides and gangliosides on mouse neural stem cells. | 2013 | Neurochem. Res. | pmid:23851714 |
| Kuwabara S and Yuki N | Axonal Guillain-Barré syndrome: concepts and controversies. | 2013 | Lancet Neurol | pmid:24229616 |
| Van Blerkom J and Caltrider K | Sperm attachment and penetration competence in the human oocyte: a possible aetiology of fertilization failure involving the organization of oolemmal lipid raft microdomains influenced by the ΔΨm of subplasmalemmal mitochondria. | 2013 | Reprod. Biomed. Online | pmid:24157131 |
| Ogawa G et al. | An antibody to the GM1/GalNAc-GD1a complex correlates with development of pure motor Guillain-Barré syndrome with reversible conduction failure. | 2013 | J. Neuroimmunol. | pmid:23000056 |
| Kreutz F et al. | Alterations on Naâº,Kâº-ATPase and acetylcholinesterase activities induced by amyloid-β peptide in rat brain and GM1 ganglioside neuroprotective action. | 2013 | Neurochem. Res. | pmid:24013887 |
| Kuwahara M et al. | Clinical features of CIDP with LM1-associated antibodies. | 2013 | J. Neurol. Neurosurg. Psychiatry | pmid:23138763 |
| Cheng Q et al. | Fuzheng Huayu inhibits carbon tetrachloride-induced liver fibrosis in mice through activating hepatic NK cells. | 2013 | J Ethnopharmacol | pmid:23127651 |
| Hosoya S et al. | Innate immune responses involving natural killer and natural killer T cells promote liver regeneration after partial hepatectomy in mice. | 2013 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:23086918 |
| Vlam L et al. | Immune pathogenesis and treatment of multifocal motor neuropathy. | 2013 | J. Clin. Immunol. | pmid:22941513 |
| Rockett BD et al. | Fish oil increases raft size and membrane order of B cells accompanied by differential effects on function. | 2012 | J. Lipid Res. | pmid:22315394 |
| Pryor S et al. | NGF causes TrkA to specifically attract microtubules to lipid rafts. | 2012 | PLoS ONE | pmid:22496904 |
| Gitz E et al. | Improved platelet survival after cold storage by prevention of glycoprotein Ibα clustering in lipid rafts. | 2012 | Haematologica | pmid:22733027 |
| Rogers TJ et al. | Role of lipid rafts and flagellin in invasion of colonic epithelial cells by Shiga-toxigenic Escherichia coli O113:H21. | 2012 | Infect. Immun. | pmid:22689816 |
| Puryear WB et al. | HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22529395 |
| Sezgin E et al. | Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes. | 2012 | Biochim. Biophys. Acta | pmid:22450237 |
| Essaka DC et al. | Single cell ganglioside catabolism in primary cerebellar neurons and glia. | 2012 | Neurochem. Res. | pmid:22407243 |
| Di Pardo A et al. | Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22331905 |
| Sekiguchi Y et al. | Antiganglioside antibodies are associated with axonal Guillain-Barré syndrome: a Japanese-Italian collaborative study. | 2012 | J. Neurol. Neurosurg. Psychiatry | pmid:22010183 |
| Olvera-Gomez I et al. | Cholera toxin activates nonconventional adjuvant pathways that induce protective CD8 T-cell responses after epicutaneous vaccination. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22308317 |
| Fewou SN et al. | Anti-ganglioside antibody internalization attenuates motor nerve terminal injury in a mouse model of acute motor axonal neuropathy. | 2012 | J. Clin. Invest. | pmid:22307327 |
| Mauri L et al. | Anti-GM1/GD1a complex antibodies in GBS sera specifically recognize the hybrid dimer GM1-GD1a. | 2012 | Glycobiology | pmid:21921061 |
| Evangelisti E et al. | Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers. | 2012 | J. Cell. Sci. | pmid:22344258 |
| Lee KY | Anti-GQ1b-negative Miller Fisher syndrome after Campylobacter jejuni enteritis. | 2012 | Pediatr. Neurol. | pmid:22883289 |
| Moyano AL et al. | Novel antibodies reacting with two neighboring gangliosides are induced in rabbits immunized with bovine brain gangliosides. | 2012 | Glycobiology | pmid:22843673 |
| Breimer ME et al. | Glycosphingolipid composition of epithelial cells isolated along the villus axis of small intestine of a single human individual. | 2012 | Glycobiology | pmid:22833314 |
| Khatun UL et al. | Modulation of the neurotensin solution structure in the presence of ganglioside GM1 bicelle. | 2012 | Biophys. Chem. | pmid:22824320 |
| Del Favero E et al. | Transient step-like kinetics of enzyme reaction on fragmented-condensed substrates. | 2012 | J Phys Chem B | pmid:22809280 |
| Li L et al. | Spatiotemporally controlled and multifactor involved assay of neuronal compartment regeneration after chemical injury in an integrated microfluidics. | 2012 | Anal. Chem. | pmid:22793989 |
| Wu G et al. | Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans. | 2012 | J. Neurosci. Res. | pmid:22714832 |
| Kato K | Structural glycomic approaches to molecular recognition events on cell surfaces. | 2012 | Adv. Exp. Med. Biol. | pmid:22695835 |
| Yamamoto N et al. | Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes. | 2012 | J. Neurochem. | pmid:22260232 |
| Pernber Z et al. | Altered distribution of the gangliosides GM1 and GM2 in Alzheimer's disease. | 2012 | Dement Geriatr Cogn Disord | pmid:22572791 |
| Mrówczyńska L et al. | Spontaneous curvature of ganglioside GM1--effect of cross-linking. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22634013 |
| Yang L et al. | Bone marrow-derived mesenchymal stem cells differentiate to hepatic myofibroblasts by transforming growth factor-β1 via sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis. | 2012 | Am. J. Pathol. | pmid:22609227 |
| Miyata T et al. | Physicochemically stable cholera toxin B subunit pentamer created by peripheral molecular constraints imposed by de novo-introduced intersubunit disulfide crosslinks. | 2012 | Vaccine | pmid:22542816 |
| Stojanov K et al. | In vivo biodistribution of prion- and GM1-targeted polymersomes following intravenous administration in mice. | 2012 | Mol. Pharm. | pmid:22536790 |
| Ledeen RW et al. | Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1 [corrected]. | 2012 | Ann. N. Y. Acad. Sci. | pmid:22524425 |
| Jiang S et al. | A proteomics approach to the cell-surface interactome using the enzyme-mediated activation of radical sources reaction. | 2012 | Proteomics | pmid:22106087 |
| Bucciantini M et al. | Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1. | 2012 | FASEB J. | pmid:22071505 |
| Kawakami S et al. | A-waves in Guillain-Barré syndrome: correlation with electrophysiological subtypes and antiganglioside antibodies. | 2012 | Clin Neurophysiol | pmid:22055840 |
| Becker PM et al. | In vitro inhibition of ETEC K88 adhesion by pea hulls and of LT enterotoxin binding by faba bean hulls. | 2012 | J Anim Physiol Anim Nutr (Berl) | pmid:21929729 |
| Maurissen I et al. | First case of anti-ganglioside GM1-positive Guillain-Barré syndrome due to hepatitis E virus infection. | 2012 | Infection | pmid:21877179 |
| Israeli E et al. | Guillain-Barré syndrome--a classical autoimmune disease triggered by infection or vaccination. | 2012 | Clin Rev Allergy Immunol | pmid:20890797 |