| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Voumvourakis C et al. | Serum anti-GM1 and anti-GD1a antibodies in patients with motor neuron disease. | 1992 | Acta Neurol. Scand. | pmid:1481647 |
| Jou I et al. | Gangliosides trigger inflammatory responses via TLR4 in brain glia. | 2006 | Am. J. Pathol. | pmid:16651628 |
| Ogura K et al. | Peroxidase-amplified assay of sialidase activity toward gangliosides. | 1992 | Anal. Biochem. | pmid:1595901 |
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| Schwarz A et al. | Isolation of gangliosides by cloud-point extraction with a nonionic detergent. | 1997 | Anal. Biochem. | pmid:9417780 |
| Schnaar RL et al. | Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides. | 2002 | Anal. Biochem. | pmid:11878808 |
| Caudie C et al. | [Measurement of antiganglioside autoantibodies by immunodot-blot assay: clinical importance in peripheral neuropathies]. | Ann. Biol. Clin. (Paris) | pmid:10518060 | |
| Pestronk A et al. | Patterns of serum IgM antibodies to GM1 and GD1a gangliosides in amyotrophic lateral sclerosis. | 1989 | Ann. Neurol. | pmid:2913936 |
| Kaida K et al. | Ganglioside complexes as new target antigens in Guillain-Barré syndrome. | 2004 | Ann. Neurol. | pmid:15389898 |
| Sheikh KA et al. | An anti-ganglioside antibody-secreting hybridoma induces neuropathy in mice. | 2004 | Ann. Neurol. | pmid:15293275 |
| Ho TW et al. | Anti-GD1a antibody is associated with axonal but not demyelinating forms of Guillain-Barré syndrome. | 1999 | Ann. Neurol. | pmid:9989618 |
| Carpo M et al. | Anti-GD1a ganglioside antibodies in peripheral motor syndromes. | 1996 | Ann. Neurol. | pmid:8619533 |
| Saito M and Sugiyama K | Gangliosides in rat kidney: composition, distribution, and developmental changes. | 2001 | Arch. Biochem. Biophys. | pmid:11360994 |
| Ji S et al. | Increased a-series gangliosides positively regulate leptin/Ob receptor-mediated signals in hypothalamus of GD3 synthase-deficient mice. | 2016 | Biochem. Biophys. Res. Commun. | pmid:27644882 |
| Kim SM et al. | Effects of gangliosides on the differentiation of human mesenchymal stem cells into osteoblasts by modulating epidermal growth factor receptors. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18471991 |
| Lee DH et al. | Effects of daunorubicin on ganglioside expression and neuronal differentiation of mouse embryonic stem cells. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17707770 |
| Hu D et al. | Apparent suppression of MMP-9 activity by GD1a as determined by gelatin zymography. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16942752 |
| Inoki Y et al. | Ganglioside GD3 and its mimetics induce cytochrome c release from mitochondria. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11027612 |
| Chung ES and Jin BK | Disialogangliosides induce neurodegeneration in rat mesencephalic cultures. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16764823 |
| Lang Z et al. | Ganglioside GD1a enhances VEGF-induced endothelial cell proliferation and migration. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11352656 |
| Kanda N | Gangliosides GD1a and GM3 induce interleukin-10 production by human T cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10066419 |
| Hyuga S et al. | Inhibition of highly metastatic FBJ-LL cell migration by ganglioside GD1a highly expressed in poorly metastatic FBJ-S1 cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9070274 |
| Bianco ID et al. | Modulation of phospholipase A2 activity by neutral and anionic glycosphingolipids in monolayers. | 1989 | Biochem. J. | pmid:2930519 |
| Odintsova E et al. | Gangliosides play an important role in the organization of CD82-enriched microdomains. | 2006 | Biochem. J. | pmid:16859490 |
| Trinchera M et al. | The N-acetylgalactosamine residue of exogenous GM2 ganglioside is recycled for glycoconjugate biosynthesis in rat liver. | 1990 | Biochem. J. | pmid:2310367 |
| Palestini P et al. | Change of ganglioside accessibility at the plasma membrane surface of cultured neurons, following protein kinase C activation. | 1998 | Biochemistry | pmid:9485467 |
| Wybenga LE et al. | Glycophorin as a receptor for Sendai virus. | 1996 | Biochemistry | pmid:8755731 |
| Golovanova NK et al. | Sialidase activity in normal and atherosclerotic human aortic intima. | 2002 | Biochemistry Mosc. | pmid:12495418 |
| Mikhailenko IA et al. | Interaction of low-density lipoproteins with gangliosides. | 1991 | Biochim. Biophys. Acta | pmid:1911863 |
| Dahiya R and Brasitus TA | Glycosphingolipid patterns of fetal and adult small intestinal mucosa in the sheep. | 1986 | Biochim. Biophys. Acta | pmid:3942764 |
| Melikyan GB et al. | The influence of gangliosides on the hydrophilic pore edge line tension and monolayer fusion of lipid membranes. | 1990 | Biochim. Biophys. Acta | pmid:2265186 |
| Suzuki Y et al. | Gangliosides in the blood plasma: levels of ganglio-series gangliosides in the plasma after administration of brain gangliosides. | 1988 | Biochim. Biophys. Acta | pmid:3048415 |
| Tsao YS et al. | Thermodynamic and phase characterization of phosphatidylethanolamine and ganglioside GD1a mixtures. | 1987 | Biochim. Biophys. Acta | pmid:3593711 |
| Fidelio GD et al. | Molecular parameters and physical state of neutral glycosphingolipids and gangliosides in monolayers at different temperatures. | 1986 | Biochim. Biophys. Acta | pmid:3942728 |
| Peters MW et al. | Evidence of a distribution difference between two gangliosides in bilayer membranes. | 1984 | Biochim. Biophys. Acta | pmid:6548930 |
| Sarkar CP and Cenedella RJ | Gangliosides in normal and cataractous lenses of several species. | 1982 | Biochim. Biophys. Acta | pmid:7104379 |
| Bertoli E et al. | Electron paramagnetic resonance studies on the fluidity and surface dynamics of egg phosphatidylcholine vesicles containing gangliosides. | 1981 | Biochim. Biophys. Acta | pmid:6271209 |
| Hinz HJ et al. | Influence of gangliosides GM1 and GD1a on structural and thermotropic properties of sonicated small 1,2-dipalmitoyl-L-alpha-phosphatidylcholine vesicles. | 1981 | Biochim. Biophys. Acta | pmid:6894700 |
| Heredia V et al. | Interfacial stabilization of the antitumoral drug Paclitaxel in monolayers of GM1 and GD1a gangliosides. | 2015 | Biochim. Biophys. Acta | pmid:26119566 |
| Rosales Fritz VM et al. | Chinese hamster ovary cells lacking GM1 and GD1a synthesize gangliosides upon transfection with human GM2 synthase. | 1997 | Biochim. Biophys. Acta | pmid:9396632 |
| Viljetić B et al. | Distribution of mono-, di- and trisialo gangliosides in the brain of Actinopterygian fishes. | 2012 | Biochim. Biophys. Acta | pmid:22206893 |
| Zhang L et al. | Ganglioside GD1a negatively regulates hepatocyte growth factor expression through caveolin-1 at the transcriptional level in murine osteosarcoma cells. | 2011 | Biochim. Biophys. Acta | pmid:21554929 |
| Ruggiero FM et al. | Membrane binding, endocytic trafficking and intracellular fate of high-affinity antibodies to gangliosides GD1a and GM1. | 2017 | Biochim. Biophys. Acta | pmid:27806911 |
| Filipovic I et al. | Sphingolipid-induced enhancement of receptor-mediated uptake of low density lipoproteins in normal and receptor-deficient human skin fibroblasts. | 1981 | Biochim. Biophys. Acta | pmid:6271205 |
| Heffer-Lauc M et al. | Membrane redistribution of gangliosides and glycosylphosphatidylinositol-anchored proteins in brain tissue sections under conditions of lipid raft isolation. | 2005 | Biochim. Biophys. Acta | pmid:15629689 |
| Tatsumi K et al. | Enhanced expression of a-series gangliosides in fibroblasts of patients with peroxisome biogenesis disorders. | 2001 | Biochim. Biophys. Acta | pmid:11278168 |
| Rapoport E et al. | Ganglioside binding pattern of CD33-related siglecs. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12639556 |
| Hirai M and Takizawa T | Intensive extrusion and occlusion of water in ganglioside micelles with thermal reversibility. | 1998 | Biophys. J. | pmid:9635755 |
| Hirai M et al. | Interaction of gangliosides with proteins depending on oligosaccharide chain and protein surface modification. | 1998 | Biophys. J. | pmid:9512034 |
| McDaniel RV et al. | Electrokinetic and electrostatic properties of bilayers containing gangliosides GM1, GD1a, or GT1. Comparison with a nonlinear theory. | 1986 | Biophys. J. | pmid:3697476 |
| Poppe L et al. | Carbohydrate dynamics at a micellar surface: GD1a headgroup transformations revealed by NMR spectroscopy. | 1994 | Biophys. J. | pmid:8061213 |
| Inagaki M et al. | Effects of ganglioside GD1a on the fluidity and phase transition of phosphatidylcholine model membrane immobilized on porous cellulose acetate filter. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8988630 |
| Rocheleau JV and Petersen NO | Sendai virus binds to a dispersed population of NBD-GD1a. | 2000 | Biosci. Rep. | pmid:11095114 |
| McGonigal R et al. | Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. | 2010 | Brain | pmid:20513658 |
| Lopez PH et al. | Structural requirements of anti-GD1a antibodies determine their target specificity. | 2008 | Brain | pmid:18487279 |
| Gong Y et al. | Localization of major gangliosides in the PNS: implications for immune neuropathies. | 2002 | Brain | pmid:12390975 |
| Park JY et al. | GM1 induces p38 and microtubule dependent ramification of rat primary microglia in vitro. | 2008 | Brain Res. | pmid:18930716 |
| Yoshino H et al. | Identification of gangliosides recognized by IgG anti-GalNAc-GD1a antibodies in bovine spinal motor neurons and motor nerves. | 2008 | Brain Res. | pmid:18598683 |
| Kotani M et al. | Developmental changes of ganglioside expressions in postnatal rat cerebellar cortex. | 1995 | Brain Res. | pmid:8624728 |
| Sung CC et al. | Gangliosides as diagnostic markers of human astrocytomas and primitive neuroectodermal tumors. | 1994 | Cancer | pmid:7954264 |
| Murayama K et al. | Qualitative differences in position of sialylation and surface expression of glycolipids between murine lymphomas with low metastatic (Eb) and high metastatic (ESb) potentials and isolation of a novel disialoganglioside (GD1 alpha) from Eb cells. | 1986 | Cancer Res. | pmid:3484680 |
| Taki T et al. | Ganglioside GD1alpha functions in the adhesion of metastatic tumor cells to endothelial cells of the target tissue. | 1997 | Cancer Res. | pmid:9157980 |
| Hasegawa A et al. | A facile, systematic synthesis of ganglio-series gangliosides: total synthesis of gangliosides GM1 and GD1a. | 1992 | Carbohydr. Res. | pmid:1473099 |
| Prabhanjan H et al. | Synthesis of disialoganglioside GD1 alpha and its positional isomer. | 1992 | Carbohydr. Res. | pmid:1446313 |
| Fronza G et al. | Synthesis and structural characterization of the dilactone derivative of GD1a ganglioside. | 1988 | Carbohydr. Res. | pmid:3242802 |
| Komori T et al. | Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates. | 2009 | Carbohydr. Res. | pmid:19560125 |
| Aydin M et al. | Age-related changes in GM1, GD1a, GT1b components of gangliosides in Wistar albino rats. | 2000 | Cell Biochem. Funct. | pmid:10686582 |
| Mirkin BL et al. | Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B. | 2002 | Cell Prolif. | pmid:11952645 |
| Watanabe Y et al. | Effect of gangliosides on murine megakaryocytopoiesis in a liquid culture system. | 1988 | Cell Struct. Funct. | pmid:3180256 |
| Taki T et al. | Appearance of a novel type of ganglioside (GD1 alpha) in a differentiation-resistant clone of mouse myeloid leukemia cells, M1-R1. | 1988 | Cell Struct. Funct. | pmid:3163528 |
| Shen W and Ladisch S | Ganglioside GD1a impedes lipopolysaccharide-induced maturation of human dendritic cells. | 2002 | Cell. Immunol. | pmid:12657247 |
| Krifuks O et al. | The down-modulation of CD4 induced by the GM1 ganglioside is regulated by phosphatases and kinases: evidence from enzyme inhibitors and anti-CD45 antibodies. | 1998 | Cell. Immunol. | pmid:9682003 |
| Brocca P et al. | Aggregation properties of semisynthetic GD1a ganglioside (IV3Neu5AcII3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety. | 1995 | Chem. Phys. Lipids | pmid:7586091 |
| van Gorkom LC et al. | Ganglioside GD1a generates domains of high curvature in phosphatidylethanolamine liposomes as determined by solid state 31P-NMR spectroscopy. | 1995 | Chem. Phys. Lipids | pmid:7788794 |
| Vachalová I et al. | Anti-GM2, -GD1a and -GD1b positive purely isolated facial diplegia. | 2014 | Clin Neurol Neurosurg | pmid:24813327 |
| Baumann N | Specificity of antiglycolipid antibodies. | 2000 | Clin Rev Allergy Immunol | pmid:11064824 |
| Zeigler M and Bach G | Internalization of exogenous gangliosides in cultured skin fibroblasts for the diagnosis of mucolipidosis IV. | 1986 | Clin. Chim. Acta | pmid:3087662 |
| Davidsson P et al. | Determination of gangliosides and sulfatide in human cerebrospinal fluid with a microimmunoaffinity technique. | 1991 | Clin. Chim. Acta | pmid:2049855 |
| Hu D et al. | Ganglioside GD1a negatively regulates matrix metalloproteinase-9 expression in mouse FBJ cell lines at the transcriptional level. | 2007 | Connect. Tissue Res. | pmid:17653976 |
| Santos AX et al. | GD1a modulates GM-CSF-induced cell proliferation. | 2011 | Cytokine | pmid:21930390 |
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| Yang HJ et al. | Inhibition of ganglioside GD1a synthesis suppresses the differentiation of human mesenchymal stem cells into osteoblasts. | 2011 | Dev. Growth Differ. | pmid:21492147 |
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Ganglioside GD1
Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GD1?
Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GD1
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GD1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GD1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GD1?
Related references are published most in these journals:
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What genes are associated with Ganglioside GD1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GD1?
There are no associated biomedical information in the current reference collection.