| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Kanda N | Gangliosides GD1a and GM3 induce interleukin-10 production by human T cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10066419 |
| Maggio B | Modulation of phospholipase A2 by electrostatic fields and dipole potential of glycosphingolipids in monolayers. | 1999 | J. Lipid Res. | pmid:10224162 |
| Kozaki S | [Studies on the receptor for Clostridium botulinum neurotoxin]. | 1999 | Nippon Saikingaku Zasshi | pmid:10356952 |
| Scorrano L et al. | Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore. | 1999 | J. Biol. Chem. | pmid:10428836 |
| Caudie C et al. | [Measurement of antiganglioside autoantibodies by immunodot-blot assay: clinical importance in peripheral neuropathies]. | Ann. Biol. Clin. (Paris) | pmid:10518060 | |
| Hyuga S et al. | Suppression by ganglioside GD1A of migration capability, adhesion to vitronectin and metastatic potential of highly metastatic FBJ-LL cells. | 1999 | Int. J. Cancer | pmid:10521808 |
| Yuki N et al. | Acute motor axonal neuropathy and acute motor-sensory axonal neuropathy share a common immunological profile. | 1999 | J. Neurol. Sci. | pmid:10526194 |
| Zuberbier T et al. | Alterations in ganglioside expression during the differentiation of human mast cells. | 1999 | Exp. Dermatol. | pmid:10536964 |
| Matà S et al. | Multiple sclerosis is associated with enhanced B cell responses to the ganglioside GD1a. | 1999 | Mult. Scler. | pmid:10618693 |
| Aydin M et al. | Age-related changes in GM1, GD1a, GT1b components of gangliosides in Wistar albino rats. | 2000 | Cell Biochem. Funct. | pmid:10686582 |
| Yoshino H et al. | IgG antiganglioside antibodies in Guillain-Barré syndrome with bulbar palsy. | 2000 | J. Neuroimmunol. | pmid:10742563 |
| Lunn MP et al. | High-affinity anti-ganglioside IgG antibodies raised in complex ganglioside knockout mice: reexamination of GD1a immunolocalization. | 2000 | J. Neurochem. | pmid:10854286 |
| Kanda N and Watanabe S | Ganglioside GD1a enhances immunoglobulin production by human peripheral blood mononuclear cells. | 2000 | Exp. Hematol. | pmid:10880753 |
| Montero EF et al. | Kidney and small intestine morphologic aspects following systemic use of gangliosides. | 2000 | Transplant. Proc. | pmid:10995967 |
| Inoki Y et al. | Ganglioside GD3 and its mimetics induce cytochrome c release from mitochondria. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11027612 |
| Baumann N | Specificity of antiglycolipid antibodies. | 2000 | Clin Rev Allergy Immunol | pmid:11064824 |
| Rocheleau JV and Petersen NO | Sendai virus binds to a dispersed population of NBD-GD1a. | 2000 | Biosci. Rep. | pmid:11095114 |
| Metelmann W et al. | Nano-electrospray ionization time-of-flight mass spectrometry of gangliosides from human brain tissue. | 2001 | J Mass Spectrom | pmid:11180643 |
| Kopitz J et al. | Desialylation of extracellular GD1a-neoganglioprotein suggests cell surface orientation of the plasma membrane-bound ganglioside sialidase activity in human neuroblastoma cells. | 2001 | FEBS Lett. | pmid:11240133 |
| Roy D and Mukhopadhyay C | GD1a in phospholipid bilayer: a molecular dynamics simulation. | 2001 | J. Biomol. Struct. Dyn. | pmid:11245258 |
| Tatsumi K et al. | Enhanced expression of a-series gangliosides in fibroblasts of patients with peroxisome biogenesis disorders. | 2001 | Biochim. Biophys. Acta | pmid:11278168 |
| Lang Z et al. | Ganglioside GD1a enhances VEGF-induced endothelial cell proliferation and migration. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11352656 |
| Saito M and Sugiyama K | Gangliosides in rat kidney: composition, distribution, and developmental changes. | 2001 | Arch. Biochem. Biophys. | pmid:11360994 |
| Zaprianova E et al. | Serum ganglioside patterns in multiple sclerosis. | 2001 | Neurochem. Res. | pmid:11478747 |
| Mizutani K et al. | Sensorimotor demyelinating neuropathy with IgM antibody against gangliosides GD1a, GT1b and GM3. | 2001 | J. Neurol. Sci. | pmid:11489278 |
| Metelmann W et al. | Gangliosides from human granulocytes: a nano-ESI QTOF mass spectrometry fucosylation study of low abundance species in complex mixtures. | 2001 | J. Am. Soc. Mass Spectrom. | pmid:11506229 |
| Press R et al. | Temporal profile of anti-ganglioside antibodies and their relation to clinical parameters and treatment in Guillain-Barré syndrome. | 2001 | J. Neurol. Sci. | pmid:11574105 |
| De Angelis MV et al. | Anti-GD1a antibodies from an acute motor axonal neuropathy patient selectively bind to motor nerve fiber nodes of Ranvier. | 2001 | J. Neuroimmunol. | pmid:11730943 |
| Schnaar RL et al. | Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides. | 2002 | Anal. Biochem. | pmid:11878808 |
| Mirkin BL et al. | Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B. | 2002 | Cell Prolif. | pmid:11952645 |
| Alaedini A et al. | Detection of anti-ganglioside antibodies in Guillain-Barré syndrome and its variants by the agglutination assay. | 2002 | J. Neurol. Sci. | pmid:11959155 |
| Masserini M et al. | Preparation and use of liposomes for the study of sphingolipid segregation in membrane model systems. | 2002 | Methods Mol. Biol. | pmid:12094568 |
| Nachamkin I et al. | Campylobacter jejuni from patients with Guillain-Barré syndrome preferentially expresses a GD(1a)-like epitope. | 2002 | Infect. Immun. | pmid:12183587 |
| Tagawa Y et al. | Anti-ganglioside antibodies bind with enhanced affinity to gangliosides containing very long chain fatty acids. | 2002 | Neurochem. Res. | pmid:12374222 |
| Gong Y et al. | Localization of major gangliosides in the PNS: implications for immune neuropathies. | 2002 | Brain | pmid:12390975 |
| Golovanova NK et al. | Sialidase activity in normal and atherosclerotic human aortic intima. | 2002 | Biochemistry Mosc. | pmid:12495418 |
| Rapoport E et al. | Ganglioside binding pattern of CD33-related siglecs. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12639556 |
| Shen W and Ladisch S | Ganglioside GD1a impedes lipopolysaccharide-induced maturation of human dendritic cells. | 2002 | Cell. Immunol. | pmid:12657247 |
| Hirano M et al. | A family with Campylobacter enteritis: anti-GD1a antibody with/without Guillain-Barré syndrome. | 2003 | Neurology | pmid:12771281 |
| Caldwell S et al. | Mechanisms of ganglioside inhibition of APC function. | 2003 | J. Immunol. | pmid:12902465 |
| Tsai B et al. | Gangliosides are receptors for murine polyoma virus and SV40. | 2003 | EMBO J. | pmid:12941687 |
| Yoshino H et al. | Isolated bovine spinal motoneurons have specific ganglioside antigens recognized by sera from patients with motor neuron disease and motor neuropathy. | 1992 | J. Neurochem. | pmid:1383424 |
| Kobayashi T et al. | A functional barrier to movement of lipids in polarized neurons. | 1992 | Nature | pmid:1406997 |
| Prabhanjan H et al. | Synthesis of disialoganglioside GD1 alpha and its positional isomer. | 1992 | Carbohydr. Res. | pmid:1446313 |
| Odintsova E et al. | Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR. | 2003 | J. Cell. Sci. | pmid:14576349 |
| Hasegawa A et al. | A facile, systematic synthesis of ganglio-series gangliosides: total synthesis of gangliosides GM1 and GD1a. | 1992 | Carbohydr. Res. | pmid:1473099 |
| Voumvourakis C et al. | Serum anti-GM1 and anti-GD1a antibodies in patients with motor neuron disease. | 1992 | Acta Neurol. Scand. | pmid:1481647 |
| Yuki N et al. | Severe acute axonal form of Guillain-Barré syndrome associated with IgG anti-GD1a antibodies. | 1992 | Muscle Nerve | pmid:1495505 |
| Papini N et al. | The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions. | 2004 | J. Biol. Chem. | pmid:14970224 |
| Chonn A et al. | Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes. | 1992 | J. Biol. Chem. | pmid:1527006 |
| Sheikh KA et al. | An anti-ganglioside antibody-secreting hybridoma induces neuropathy in mice. | 2004 | Ann. Neurol. | pmid:15293275 |
| Kaida K et al. | Ganglioside complexes as new target antigens in Guillain-Barré syndrome. | 2004 | Ann. Neurol. | pmid:15389898 |
| Gilbert J and Benjamin T | Uptake pathway of polyomavirus via ganglioside GD1a. | 2004 | J. Virol. | pmid:15507613 |
| Müthing J et al. | Tumor-associated CD75s gangliosides and CD75s-bearing glycoproteins with Neu5Acalpha2-6Galbeta1-4GlcNAc-residues are receptors for the anticancer drug rViscumin. | 2005 | FASEB J. | pmid:15520251 |
| Galassi G et al. | Post-infectious acute ataxia and facial diplegia associated with anti-GD1a IgG antibody. | 2004 | Eur. J. Neurol. | pmid:15525304 |
| Gilbert J et al. | Ganglioside GD1a restores infectibility to mouse cells lacking functional receptors for polyomavirus. | 2005 | J. Virol. | pmid:15596855 |
| Heffer-Lauc M et al. | Membrane redistribution of gangliosides and glycosylphosphatidylinositol-anchored proteins in brain tissue sections under conditions of lipid raft isolation. | 2005 | Biochim. Biophys. Acta | pmid:15629689 |
| Dasgupta S et al. | Lack of apparent neurological abnormalities in rabbits sensitized by gangliosides. | 2004 | Neurochem. Res. | pmid:15662849 |
| Goodfellow JA et al. | Overexpression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody-mediated injury in a model of acute motor axonal neuropathy. | 2005 | J. Neurosci. | pmid:15716397 |
| Ogura K et al. | Peroxidase-amplified assay of sialidase activity toward gangliosides. | 1992 | Anal. Biochem. | pmid:1595901 |
| Shen W et al. | Modulation of CD4 Th cell differentiation by ganglioside GD1a in vitro. | 2005 | J. Immunol. | pmid:16210594 |
| Pandey JP et al. | Immunoglobulin KM allotypes are associated with the prevalence of autoantibodies to GD1a ganglioside, but not with susceptibility to the disease, in Japanese patients with Guillain-Barré syndrome. | 2005 | Neurogenetics | pmid:16258760 |
| Gavella M et al. | Trisialoganglioside GT1b prevents increase in sperm membrane molecular ordering induced by in vitro lipid peroxidation. | J. Androl. | pmid:16291967 | |
| Caporale CM et al. | Experimental axonopathy induced by immunization with Campylobacter jejuni lipopolysaccharide from a patient with Guillain-Barré syndrome. | 2006 | J. Neuroimmunol. | pmid:16516981 |
| Jou I et al. | Gangliosides trigger inflammatory responses via TLR4 in brain glia. | 2006 | Am. J. Pathol. | pmid:16651628 |
| Rojas-Garcia R et al. | A novel antiganglioside specificity against terminal NeuNAc(alfa 2-3)Gal in acute bulbar palsy. | 2006 | J. Neuroimmunol. | pmid:16707165 |
| Marconi S et al. | Anti-GD2-like IgM autoreactivity in multiple sclerosis patients. | 2006 | Mult. Scler. | pmid:16764343 |
| Chung ES and Jin BK | Disialogangliosides induce neurodegeneration in rat mesencephalic cultures. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16764823 |
| Date I et al. | Stereotaxic injection of GD1a ganglioside induces limited recovery of striatal dopaminergic system in MPTP-treated aging mice. | 1991 | J. Neurosci. Res. | pmid:1678435 |
| Odintsova E et al. | Gangliosides play an important role in the organization of CD82-enriched microdomains. | 2006 | Biochem. J. | pmid:16859490 |
| Wang L et al. | Ganglioside GD1a regulation of caveolin-1 and Stim1 expression in mouse FBJ cells: augmented expression of caveolin-1 and Stim1 in cells with increased GD1a content. | 2006 | Glycoconj. J. | pmid:16897174 |
| Hu D et al. | Apparent suppression of MMP-9 activity by GD1a as determined by gelatin zymography. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16942752 |
| Lehmann HC et al. | Passive immunization with anti-ganglioside antibodies directly inhibits axon regeneration in an animal model. | 2007 | J. Neurosci. | pmid:17202469 |
| Liang S et al. | Ganglioside GD1a is an essential coreceptor for Toll-like receptor 2 signaling in response to the B subunit of type IIb enterotoxin. | 2007 | J. Biol. Chem. | pmid:17227759 |
| Connell TD and Holmes RK | Molecular genetic analysis of ganglioside GD1b-binding activity of Escherichia coli type IIa heat-labile enterotoxin by use of random and site-directed mutagenesis. | 1992 | Infect. Immun. | pmid:1729197 |
| Heffer-Lauc M et al. | Effects of detergents on the redistribution of gangliosides and GPI-anchored proteins in brain tissue sections. | 2007 | J. Histochem. Cytochem. | pmid:17409378 |
| Hamaguchi T et al. | Guillain-Barré syndrome with antibodies to GD1a/GD1b complex. | 2007 | J. Neurol. Neurosurg. Psychiatry | pmid:17435195 |
| Fusco C et al. | Acute ophthalmoparesis associated with anti-GM1, anti-GD1a, and anti-GD1b antibodies after enterovirus infection in a 6-year-old girl. | 2007 | J. Child Neurol. | pmid:17621523 |
| Hu D et al. | Ganglioside GD1a negatively regulates matrix metalloproteinase-9 expression in mouse FBJ cell lines at the transcriptional level. | 2007 | Connect. Tissue Res. | pmid:17653976 |
| Lee DH et al. | Effects of daunorubicin on ganglioside expression and neuronal differentiation of mouse embryonic stem cells. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17707770 |
| Nobile-Orazio E et al. | How useful are anti-neural IgM antibodies in the diagnosis of chronic immune-mediated neuropathies? | 2008 | J. Neurol. Sci. | pmid:17915254 |
| Zhang H et al. | Ganglioside GM1 binding the N-terminus of amyloid precursor protein. | 2009 | Neurobiol. Aging | pmid:18077059 |
| Pavić R et al. | Activity cage as a method to analyze functional recovery after sciatic nerve injury in mice. | 2007 | Somatosens Mot Res | pmid:18097994 |
| Meier EM et al. | The human GM2 activator protein. A substrate specific cofactor of beta-hexosaminidase A. | 1991 | J. Biol. Chem. | pmid:1824846 |
| Shukla GS et al. | Gangliosides inhibit glucosylceramide synthase: a possible role in ganglioside therapy. | 1991 | J. Neurochem. | pmid:1827496 |
| Shen W et al. | Inhibition of TLR activation and up-regulation of IL-1R-associated kinase-M expression by exogenous gangliosides. | 2008 | J. Immunol. | pmid:18354163 |
| Kim SM et al. | Effects of gangliosides on the differentiation of human mesenchymal stem cells into osteoblasts by modulating epidermal growth factor receptors. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18471991 |
| Lopez PH et al. | Structural requirements of anti-GD1a antibodies determine their target specificity. | 2008 | Brain | pmid:18487279 |
| Yoshino H et al. | Identification of gangliosides recognized by IgG anti-GalNAc-GD1a antibodies in bovine spinal motor neurons and motor nerves. | 2008 | Brain Res. | pmid:18598683 |
| Palestini P et al. | Evidence for nonrandom distribution of GD1a ganglioside in rabbit brain microsomal membranes. | 1991 | J. Neurochem. | pmid:1861146 |
| Riboni L et al. | Cerebellar granule cells in culture exhibit a ganglioside-sialidase presumably linked to the plasma membrane. | 1991 | FEBS Lett. | pmid:1879535 |
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| Seyfried TN et al. | Brain lipid analysis in mice with Rett syndrome. | 2009 | Neurochem. Res. | pmid:19002580 |
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| Schnaar RL and Lopez PH | Myelin-associated glycoprotein and its axonal receptors. | 2009 | J. Neurosci. Res. | pmid:19156870 |
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Ganglioside GD1
Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GD1?
Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GD1
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GD1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GD1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GD1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GD1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GD1?
There are no associated biomedical information in the current reference collection.