| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Qin J et al. | GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis. | 2017 | J. Neurosci. | pmid:28899916 |
| Ruggiero FM et al. | Membrane binding, endocytic trafficking and intracellular fate of high-affinity antibodies to gangliosides GD1a and GM1. | 2017 | Biochim. Biophys. Acta | pmid:27806911 |
| Ji S et al. | Increased a-series gangliosides positively regulate leptin/Ob receptor-mediated signals in hypothalamus of GD3 synthase-deficient mice. | 2016 | Biochem. Biophys. Res. Commun. | pmid:27644882 |
| Kim DS et al. | Porcine Sapelovirus Uses α2,3-Linked Sialic Acid on GD1a Ganglioside as a Receptor. | 2016 | J. Virol. | pmid:26865725 |
| Heredia V et al. | Interfacial stabilization of the antitumoral drug Paclitaxel in monolayers of GM1 and GD1a gangliosides. | 2015 | Biochim. Biophys. Acta | pmid:26119566 |
| Koga M et al. | Complex of GM1- and GD1a-like lipo-oligosaccharide mimics GM1b, inducing anti-GM1b antibodies. | 2015 | PLoS ONE | pmid:25867522 |
| Wang Y et al. | Ganglioside GD1a suppresses LPS-induced pro-inflammatory cytokines in RAW264.7 macrophages by reducing MAPKs and NF-κB signaling pathways through TLR4. | 2015 | Int. Immunopharmacol. | pmid:26054879 |
| Miklavcic JJ et al. | Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease. | 2015 | World J. Gastroenterol. | pmid:26401073 |
| Tsukamoto K et al. | CRISPR/Cas9-Mediated Genomic Deletion of the Beta-1, 4 N-acetylgalactosaminyltransferase 1 Gene in Murine P19 Embryonal Carcinoma Cells Results in Low Sensitivity to Botulinum Neurotoxin Type C. | 2015 | PLoS ONE | pmid:26177297 |
| Xu X et al. | A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis. | 2015 | Dis Model Mech | pmid:26035393 |
| Zheng Y et al. | Efficient biotransformation of polysialogangliosides for preparation of GM1 by Cellulosimicrobium sp. 21. | 2014 | Molecules | pmid:25299818 |
| Morgan ML et al. | Anti-asialo-GM1 and GD1a variant of Miller Fisher variant of Guillain-Barré Syndrome. | 2014 | J Neuroophthalmol | pmid:25062498 |
| Bergante S et al. | Gangliosides as a potential new class of stem cell markers: the case of GD1a in human bone marrow mesenchymal stem cells. | 2014 | J. Lipid Res. | pmid:24449473 |
| Vachalová I et al. | Anti-GM2, -GD1a and -GD1b positive purely isolated facial diplegia. | 2014 | Clin Neurol Neurosurg | pmid:24813327 |
| Berntsson RP et al. | Structure of dual receptor binding to botulinum neurotoxin B. | 2013 | Nat Commun | pmid:23807078 |
| Uncini A et al. | Natura non facit saltus in anti-ganglioside antibody-mediated neuropathies. | 2013 | Muscle Nerve | pmid:23625341 |
| Wakerley BR et al. | Atypical Bickerstaff brainstem encephalitis: ataxic hypersomnolence without ophthalmoplegia. | 2013 | J. Neurol. Neurosurg. Psychiatry | pmid:23564757 |
| Kim SY et al. | Polycranial neuropathy and sensory ataxia with IgG anti-GD1a antibody as a variant of Guillain-Barré syndrome. | 2013 | J Clin Neurosci | pmid:23164827 |
| Ogawa G et al. | An antibody to the GM1/GalNAc-GD1a complex correlates with development of pure motor Guillain-Barré syndrome with reversible conduction failure. | 2013 | J. Neuroimmunol. | pmid:23000056 |
| Lee HC et al. | Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. | 2012 | J. Immunol. | pmid:22956583 |
| Venkateshwari S and Veluraja K | Molecular Modelling and Molecular Dynamics studies of GD1A, GD1B and their complexes with BoNT/B--perspectives in interaction and specificity. | 2012 | J. Struct. Biol. | pmid:22929125 |
| Sturgill ER et al. | Biosynthesis of the major brain gangliosides GD1a and GT1b. | 2012 | Glycobiology | pmid:22735313 |
| Uncini A | A common mechanism and a new categorization for anti-ganglioside antibody-mediated neuropathies. | 2012 | Exp. Neurol. | pmid:22507308 |
| Yalinay Dikmen P and Emre Oge A | Recurrent GBS with GD1a anti-ganglioside antibodies. | 2012 | J. Peripher. Nerv. Syst. | pmid:22462676 |
| Viljetić B et al. | Distribution of mono-, di- and trisialo gangliosides in the brain of Actinopterygian fishes. | 2012 | Biochim. Biophys. Acta | pmid:22206893 |
| Sekiguchi Y et al. | Antiganglioside antibodies are associated with axonal Guillain-Barré syndrome: a Japanese-Italian collaborative study. | 2012 | J. Neurol. Neurosurg. Psychiatry | pmid:22010183 |
| Mauri L et al. | Anti-GM1/GD1a complex antibodies in GBS sera specifically recognize the hybrid dimer GM1-GD1a. | 2012 | Glycobiology | pmid:21921061 |
| Santos AX et al. | GD1a modulates GM-CSF-induced cell proliferation. | 2011 | Cytokine | pmid:21930390 |
| Benson MA et al. | Unique ganglioside recognition strategies for clostridial neurotoxins. | 2011 | J. Biol. Chem. | pmid:21849494 |
| Zhang L et al. | Ganglioside GD1a negatively regulates hepatocyte growth factor expression through caveolin-1 at the transcriptional level in murine osteosarcoma cells. | 2011 | Biochim. Biophys. Acta | pmid:21554929 |
| Yang HJ et al. | Inhibition of ganglioside GD1a synthesis suppresses the differentiation of human mesenchymal stem cells into osteoblasts. | 2011 | Dev. Growth Differ. | pmid:21492147 |
| Simon O et al. | Recurrent multiple cranial nerve palsy and anti-GD1a antibodies. | 2011 | Muscle Nerve | pmid:21321960 |
| Hatano K et al. | Expression of gangliosides, GD1a, and sialyl paragloboside is regulated by NF-κB-dependent transcriptional control of α2,3-sialyltransferase I, II, and VI in human castration-resistant prostate cancer cells. | 2011 | Int. J. Cancer | pmid:21165949 |
| Bax M et al. | Campylobacter jejuni lipooligosaccharides modulate dendritic cell-mediated T cell polarization in a sialic acid linkage-dependent manner. | 2011 | Infect. Immun. | pmid:21502591 |
| Del Favero E et al. | Nanoscale structural response of ganglioside-containing aggregates to the interaction with sialidase. | 2011 | J. Neurochem. | pmid:21214561 |
| Qian M and Tsai B | Lipids and proteins act in opposing manners to regulate polyomavirus infection. | 2010 | J. Virol. | pmid:20668088 |
| Cao T et al. | Ganglioside GD1a suppression of NOS2 expression via ERK1 pathway in mouse osteosarcoma FBJ cells. | 2010 | J. Cell. Biochem. | pmid:20589721 |
| McGonigal R et al. | Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. | 2010 | Brain | pmid:20513658 |
| Neuwirth C et al. | GD1a-associated pure motor Guillain-Barré syndrome with hyperreflexia and bilateral papillitis. | 2010 | J Clin Neuromuscul Dis | pmid:20215983 |
| Yuki N | Human gangliosides and bacterial lipo-oligosaccharides in the development of autoimmune neuropathies. | 2010 | Methods Mol. Biol. | pmid:19882120 |
| Rojas-Garcia R et al. | Bulbar involvement in patients with antiganglioside antibodies against NeuNAc(alpha2-3)Gal. | 2010 | J. Neurol. Neurosurg. Psychiatry | pmid:19726412 |
| de Freitas RM et al. | Neurochemical changes on oxidative stress in rat hippocampus during acute phase of pilocarpine-induced seizures. | 2010 | Pharmacol. Biochem. Behav. | pmid:19800361 |
| Wang J et al. | Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a. | 2009 | J. Neurochem. | pmid:19686243 |
| Komori T et al. | Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates. | 2009 | Carbohydr. Res. | pmid:19560125 |
| Qian M et al. | A lipid receptor sorts polyomavirus from the endolysosome to the endoplasmic reticulum to cause infection. | 2009 | PLoS Pathog. | pmid:19503604 |
| Schnaar RL and Lopez PH | Myelin-associated glycoprotein and its axonal receptors. | 2009 | J. Neurosci. Res. | pmid:19156870 |
| Seyfried TN et al. | Brain lipid analysis in mice with Rett syndrome. | 2009 | Neurochem. Res. | pmid:19002580 |
| Zhang H et al. | Ganglioside GM1 binding the N-terminus of amyloid precursor protein. | 2009 | Neurobiol. Aging | pmid:18077059 |
| Park JY et al. | GM1 induces p38 and microtubule dependent ramification of rat primary microglia in vitro. | 2008 | Brain Res. | pmid:18930716 |
| Lopez PH et al. | Structural requirements of anti-GD1a antibodies determine their target specificity. | 2008 | Brain | pmid:18487279 |
| Kim SM et al. | Effects of gangliosides on the differentiation of human mesenchymal stem cells into osteoblasts by modulating epidermal growth factor receptors. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18471991 |
| Shen W et al. | Inhibition of TLR activation and up-regulation of IL-1R-associated kinase-M expression by exogenous gangliosides. | 2008 | J. Immunol. | pmid:18354163 |
| Yoshino H et al. | Identification of gangliosides recognized by IgG anti-GalNAc-GD1a antibodies in bovine spinal motor neurons and motor nerves. | 2008 | Brain Res. | pmid:18598683 |
| Nobile-Orazio E et al. | How useful are anti-neural IgM antibodies in the diagnosis of chronic immune-mediated neuropathies? | 2008 | J. Neurol. Sci. | pmid:17915254 |
| Heffer-Lauc M et al. | Effects of detergents on the redistribution of gangliosides and GPI-anchored proteins in brain tissue sections. | 2007 | J. Histochem. Cytochem. | pmid:17409378 |
| Pavić R et al. | Activity cage as a method to analyze functional recovery after sciatic nerve injury in mice. | 2007 | Somatosens Mot Res | pmid:18097994 |
| Lee DH et al. | Effects of daunorubicin on ganglioside expression and neuronal differentiation of mouse embryonic stem cells. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17707770 |
| Hu D et al. | Ganglioside GD1a negatively regulates matrix metalloproteinase-9 expression in mouse FBJ cell lines at the transcriptional level. | 2007 | Connect. Tissue Res. | pmid:17653976 |
| Fusco C et al. | Acute ophthalmoparesis associated with anti-GM1, anti-GD1a, and anti-GD1b antibodies after enterovirus infection in a 6-year-old girl. | 2007 | J. Child Neurol. | pmid:17621523 |
| Hamaguchi T et al. | Guillain-Barré syndrome with antibodies to GD1a/GD1b complex. | 2007 | J. Neurol. Neurosurg. Psychiatry | pmid:17435195 |
| Liang S et al. | Ganglioside GD1a is an essential coreceptor for Toll-like receptor 2 signaling in response to the B subunit of type IIb enterotoxin. | 2007 | J. Biol. Chem. | pmid:17227759 |
| Lehmann HC et al. | Passive immunization with anti-ganglioside antibodies directly inhibits axon regeneration in an animal model. | 2007 | J. Neurosci. | pmid:17202469 |
| Jou I et al. | Gangliosides trigger inflammatory responses via TLR4 in brain glia. | 2006 | Am. J. Pathol. | pmid:16651628 |
| Hu D et al. | Apparent suppression of MMP-9 activity by GD1a as determined by gelatin zymography. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16942752 |
| Wang L et al. | Ganglioside GD1a regulation of caveolin-1 and Stim1 expression in mouse FBJ cells: augmented expression of caveolin-1 and Stim1 in cells with increased GD1a content. | 2006 | Glycoconj. J. | pmid:16897174 |
| Odintsova E et al. | Gangliosides play an important role in the organization of CD82-enriched microdomains. | 2006 | Biochem. J. | pmid:16859490 |
| Chung ES and Jin BK | Disialogangliosides induce neurodegeneration in rat mesencephalic cultures. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16764823 |
| Marconi S et al. | Anti-GD2-like IgM autoreactivity in multiple sclerosis patients. | 2006 | Mult. Scler. | pmid:16764343 |
| Rojas-Garcia R et al. | A novel antiganglioside specificity against terminal NeuNAc(alfa 2-3)Gal in acute bulbar palsy. | 2006 | J. Neuroimmunol. | pmid:16707165 |
| Caporale CM et al. | Experimental axonopathy induced by immunization with Campylobacter jejuni lipopolysaccharide from a patient with Guillain-Barré syndrome. | 2006 | J. Neuroimmunol. | pmid:16516981 |
| Pandey JP et al. | Immunoglobulin KM allotypes are associated with the prevalence of autoantibodies to GD1a ganglioside, but not with susceptibility to the disease, in Japanese patients with Guillain-Barré syndrome. | 2005 | Neurogenetics | pmid:16258760 |
| Shen W et al. | Modulation of CD4 Th cell differentiation by ganglioside GD1a in vitro. | 2005 | J. Immunol. | pmid:16210594 |
| Goodfellow JA et al. | Overexpression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody-mediated injury in a model of acute motor axonal neuropathy. | 2005 | J. Neurosci. | pmid:15716397 |
| Heffer-Lauc M et al. | Membrane redistribution of gangliosides and glycosylphosphatidylinositol-anchored proteins in brain tissue sections under conditions of lipid raft isolation. | 2005 | Biochim. Biophys. Acta | pmid:15629689 |
| Gilbert J et al. | Ganglioside GD1a restores infectibility to mouse cells lacking functional receptors for polyomavirus. | 2005 | J. Virol. | pmid:15596855 |
| Müthing J et al. | Tumor-associated CD75s gangliosides and CD75s-bearing glycoproteins with Neu5Acalpha2-6Galbeta1-4GlcNAc-residues are receptors for the anticancer drug rViscumin. | 2005 | FASEB J. | pmid:15520251 |
| Gilbert J and Benjamin T | Uptake pathway of polyomavirus via ganglioside GD1a. | 2004 | J. Virol. | pmid:15507613 |
| Papini N et al. | The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions. | 2004 | J. Biol. Chem. | pmid:14970224 |
| Dasgupta S et al. | Lack of apparent neurological abnormalities in rabbits sensitized by gangliosides. | 2004 | Neurochem. Res. | pmid:15662849 |
| Galassi G et al. | Post-infectious acute ataxia and facial diplegia associated with anti-GD1a IgG antibody. | 2004 | Eur. J. Neurol. | pmid:15525304 |
| Kaida K et al. | Ganglioside complexes as new target antigens in Guillain-Barré syndrome. | 2004 | Ann. Neurol. | pmid:15389898 |
| Sheikh KA et al. | An anti-ganglioside antibody-secreting hybridoma induces neuropathy in mice. | 2004 | Ann. Neurol. | pmid:15293275 |
| Rapoport E et al. | Ganglioside binding pattern of CD33-related siglecs. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12639556 |
| Tsai B et al. | Gangliosides are receptors for murine polyoma virus and SV40. | 2003 | EMBO J. | pmid:12941687 |
| Odintsova E et al. | Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR. | 2003 | J. Cell. Sci. | pmid:14576349 |
| Caldwell S et al. | Mechanisms of ganglioside inhibition of APC function. | 2003 | J. Immunol. | pmid:12902465 |
| Hirano M et al. | A family with Campylobacter enteritis: anti-GD1a antibody with/without Guillain-Barré syndrome. | 2003 | Neurology | pmid:12771281 |
| Alaedini A et al. | Detection of anti-ganglioside antibodies in Guillain-Barré syndrome and its variants by the agglutination assay. | 2002 | J. Neurol. Sci. | pmid:11959155 |
| Golovanova NK et al. | Sialidase activity in normal and atherosclerotic human aortic intima. | 2002 | Biochemistry Mosc. | pmid:12495418 |
| Nachamkin I et al. | Campylobacter jejuni from patients with Guillain-Barré syndrome preferentially expresses a GD(1a)-like epitope. | 2002 | Infect. Immun. | pmid:12183587 |
| Shen W and Ladisch S | Ganglioside GD1a impedes lipopolysaccharide-induced maturation of human dendritic cells. | 2002 | Cell. Immunol. | pmid:12657247 |
| Gong Y et al. | Localization of major gangliosides in the PNS: implications for immune neuropathies. | 2002 | Brain | pmid:12390975 |
| Tagawa Y et al. | Anti-ganglioside antibodies bind with enhanced affinity to gangliosides containing very long chain fatty acids. | 2002 | Neurochem. Res. | pmid:12374222 |
| Masserini M et al. | Preparation and use of liposomes for the study of sphingolipid segregation in membrane model systems. | 2002 | Methods Mol. Biol. | pmid:12094568 |
| Mirkin BL et al. | Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B. | 2002 | Cell Prolif. | pmid:11952645 |
| Schnaar RL et al. | Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides. | 2002 | Anal. Biochem. | pmid:11878808 |
| Metelmann W et al. | Gangliosides from human granulocytes: a nano-ESI QTOF mass spectrometry fucosylation study of low abundance species in complex mixtures. | 2001 | J. Am. Soc. Mass Spectrom. | pmid:11506229 |
| De Angelis MV et al. | Anti-GD1a antibodies from an acute motor axonal neuropathy patient selectively bind to motor nerve fiber nodes of Ranvier. | 2001 | J. Neuroimmunol. | pmid:11730943 |
| Press R et al. | Temporal profile of anti-ganglioside antibodies and their relation to clinical parameters and treatment in Guillain-Barré syndrome. | 2001 | J. Neurol. Sci. | pmid:11574105 |
| Mizutani K et al. | Sensorimotor demyelinating neuropathy with IgM antibody against gangliosides GD1a, GT1b and GM3. | 2001 | J. Neurol. Sci. | pmid:11489278 |
Ganglioside GD1
Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GD1?
Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GD1
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GD1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GD1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GD1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GD1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GD1?
There are no associated biomedical information in the current reference collection.