Ganglioside GD1

Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.

Cross Reference

Introduction

To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GD1?

Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GD1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GD1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Ganglioside GD1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ganglioside GD1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Ganglioside GD1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ganglioside GD1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GD1

Download all related citations
Per page 10 20 50 100 | Total 264
Authors Title Published Journal PubMed Link
Qin J et al. GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis. 2017 J. Neurosci. pmid:28899916
Ruggiero FM et al. Membrane binding, endocytic trafficking and intracellular fate of high-affinity antibodies to gangliosides GD1a and GM1. 2017 Biochim. Biophys. Acta pmid:27806911
Ji S et al. Increased a-series gangliosides positively regulate leptin/Ob receptor-mediated signals in hypothalamus of GD3 synthase-deficient mice. 2016 Biochem. Biophys. Res. Commun. pmid:27644882
Kim DS et al. Porcine Sapelovirus Uses α2,3-Linked Sialic Acid on GD1a Ganglioside as a Receptor. 2016 J. Virol. pmid:26865725
Heredia V et al. Interfacial stabilization of the antitumoral drug Paclitaxel in monolayers of GM1 and GD1a gangliosides. 2015 Biochim. Biophys. Acta pmid:26119566
Koga M et al. Complex of GM1- and GD1a-like lipo-oligosaccharide mimics GM1b, inducing anti-GM1b antibodies. 2015 PLoS ONE pmid:25867522
Wang Y et al. Ganglioside GD1a suppresses LPS-induced pro-inflammatory cytokines in RAW264.7 macrophages by reducing MAPKs and NF-κB signaling pathways through TLR4. 2015 Int. Immunopharmacol. pmid:26054879
Miklavcic JJ et al. Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease. 2015 World J. Gastroenterol. pmid:26401073
Tsukamoto K et al. CRISPR/Cas9-Mediated Genomic Deletion of the Beta-1, 4 N-acetylgalactosaminyltransferase 1 Gene in Murine P19 Embryonal Carcinoma Cells Results in Low Sensitivity to Botulinum Neurotoxin Type C. 2015 PLoS ONE pmid:26177297
Xu X et al. A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis. 2015 Dis Model Mech pmid:26035393
Zheng Y et al. Efficient biotransformation of polysialogangliosides for preparation of GM1 by Cellulosimicrobium sp. 21. 2014 Molecules pmid:25299818
Morgan ML et al. Anti-asialo-GM1 and GD1a variant of Miller Fisher variant of Guillain-Barré Syndrome. 2014 J Neuroophthalmol pmid:25062498
Bergante S et al. Gangliosides as a potential new class of stem cell markers: the case of GD1a in human bone marrow mesenchymal stem cells. 2014 J. Lipid Res. pmid:24449473
Vachalová I et al. Anti-GM2, -GD1a and -GD1b positive purely isolated facial diplegia. 2014 Clin Neurol Neurosurg pmid:24813327
Berntsson RP et al. Structure of dual receptor binding to botulinum neurotoxin B. 2013 Nat Commun pmid:23807078
Uncini A et al. Natura non facit saltus in anti-ganglioside antibody-mediated neuropathies. 2013 Muscle Nerve pmid:23625341
Wakerley BR et al. Atypical Bickerstaff brainstem encephalitis: ataxic hypersomnolence without ophthalmoplegia. 2013 J. Neurol. Neurosurg. Psychiatry pmid:23564757
Kim SY et al. Polycranial neuropathy and sensory ataxia with IgG anti-GD1a antibody as a variant of Guillain-Barré syndrome. 2013 J Clin Neurosci pmid:23164827
Ogawa G et al. An antibody to the GM1/GalNAc-GD1a complex correlates with development of pure motor Guillain-Barré syndrome with reversible conduction failure. 2013 J. Neuroimmunol. pmid:23000056
Lee HC et al. Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. 2012 J. Immunol. pmid:22956583