Ganglioside GD1

Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.

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Introduction

To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GD1?

Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GD1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GD1?

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What functions are associated with Ganglioside GD1?


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What lipids are associated with Ganglioside GD1?

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What genes are associated with Ganglioside GD1?

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What common seen animal models are associated with Ganglioside GD1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GD1

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Authors Title Published Journal PubMed Link
Ji S et al. Increased a-series gangliosides positively regulate leptin/Ob receptor-mediated signals in hypothalamus of GD3 synthase-deficient mice. 2016 Biochem. Biophys. Res. Commun. pmid:27644882
Chung ES and Jin BK Disialogangliosides induce neurodegeneration in rat mesencephalic cultures. 2006 Biochem. Biophys. Res. Commun. pmid:16764823
Lang Z et al. Ganglioside GD1a enhances VEGF-induced endothelial cell proliferation and migration. 2001 Biochem. Biophys. Res. Commun. pmid:11352656
Hyuga S et al. Inhibition of highly metastatic FBJ-LL cell migration by ganglioside GD1a highly expressed in poorly metastatic FBJ-S1 cells. 1997 Biochem. Biophys. Res. Commun. pmid:9070274
Bianco ID et al. Modulation of phospholipase A2 activity by neutral and anionic glycosphingolipids in monolayers. 1989 Biochem. J. pmid:2930519
Odintsova E et al. Gangliosides play an important role in the organization of CD82-enriched microdomains. 2006 Biochem. J. pmid:16859490
Trinchera M et al. The N-acetylgalactosamine residue of exogenous GM2 ganglioside is recycled for glycoconjugate biosynthesis in rat liver. 1990 Biochem. J. pmid:2310367
Palestini P et al. Change of ganglioside accessibility at the plasma membrane surface of cultured neurons, following protein kinase C activation. 1998 Biochemistry pmid:9485467
Wybenga LE et al. Glycophorin as a receptor for Sendai virus. 1996 Biochemistry pmid:8755731
Golovanova NK et al. Sialidase activity in normal and atherosclerotic human aortic intima. 2002 Biochemistry Mosc. pmid:12495418
Dahiya R and Brasitus TA Glycosphingolipid patterns of fetal and adult small intestinal mucosa in the sheep. 1986 Biochim. Biophys. Acta pmid:3942764
Melikyan GB et al. The influence of gangliosides on the hydrophilic pore edge line tension and monolayer fusion of lipid membranes. 1990 Biochim. Biophys. Acta pmid:2265186
Tsao YS et al. Thermodynamic and phase characterization of phosphatidylethanolamine and ganglioside GD1a mixtures. 1987 Biochim. Biophys. Acta pmid:3593711
Fidelio GD et al. Molecular parameters and physical state of neutral glycosphingolipids and gangliosides in monolayers at different temperatures. 1986 Biochim. Biophys. Acta pmid:3942728
Sarkar CP and Cenedella RJ Gangliosides in normal and cataractous lenses of several species. 1982 Biochim. Biophys. Acta pmid:7104379
Bertoli E et al. Electron paramagnetic resonance studies on the fluidity and surface dynamics of egg phosphatidylcholine vesicles containing gangliosides. 1981 Biochim. Biophys. Acta pmid:6271209
Hinz HJ et al. Influence of gangliosides GM1 and GD1a on structural and thermotropic properties of sonicated small 1,2-dipalmitoyl-L-alpha-phosphatidylcholine vesicles. 1981 Biochim. Biophys. Acta pmid:6894700
Viljetić B et al. Distribution of mono-, di- and trisialo gangliosides in the brain of Actinopterygian fishes. 2012 Biochim. Biophys. Acta pmid:22206893
Zhang L et al. Ganglioside GD1a negatively regulates hepatocyte growth factor expression through caveolin-1 at the transcriptional level in murine osteosarcoma cells. 2011 Biochim. Biophys. Acta pmid:21554929
Filipovic I et al. Sphingolipid-induced enhancement of receptor-mediated uptake of low density lipoproteins in normal and receptor-deficient human skin fibroblasts. 1981 Biochim. Biophys. Acta pmid:6271205