Ganglioside GD1

Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.

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Introduction

To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GD1?

Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GD1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GD1?

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What functions are associated with Ganglioside GD1?


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What lipids are associated with Ganglioside GD1?

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What genes are associated with Ganglioside GD1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ganglioside GD1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GD1

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Authors Title Published Journal PubMed Link
Yuki N et al. Acute motor axonal neuropathy and acute motor-sensory axonal neuropathy share a common immunological profile. 1999 J. Neurol. Sci. pmid:10526194
Nobile-Orazio E et al. How useful are anti-neural IgM antibodies in the diagnosis of chronic immune-mediated neuropathies? 2008 J. Neurol. Sci. pmid:17915254
Hefti F et al. Gangliosides alter morphology and growth of astrocytes and increase the activity of choline acetyltransferase in cultures of dissociated septal cells. 1985 J. Neurosci. pmid:4040555
Qin J et al. GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis. 2017 J. Neurosci. pmid:28899916
Lehmann HC et al. Passive immunization with anti-ganglioside antibodies directly inhibits axon regeneration in an animal model. 2007 J. Neurosci. pmid:17202469
Goodfellow JA et al. Overexpression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody-mediated injury in a model of acute motor axonal neuropathy. 2005 J. Neurosci. pmid:15716397
Leskawa KC and Hogan EL Quantitation of the in vitro neuroblastoma response to exogenous, purified gangliosides. 1985 J. Neurosci. Res. pmid:4009744
Schnaar RL and Lopez PH Myelin-associated glycoprotein and its axonal receptors. 2009 J. Neurosci. Res. pmid:19156870
Kremer DM et al. Factors defining target specificity in antibody-mediated neuropathy: density-dependent binding of anti-GD1a polyclonal IgG from a neurological patient. 1997 J. Neurosci. Res. pmid:9089212
Saulino MF and Schengrund CL Differential accumulation of gangliosides by the brains of MPTP-lesioned mice. 1994 J. Neurosci. Res. pmid:8176760