Ganglioside GD1

Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.

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Introduction

To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GD1?

Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GD1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GD1?

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What functions are associated with Ganglioside GD1?


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What lipids are associated with Ganglioside GD1?

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What genes are associated with Ganglioside GD1?

Related references are published most in these journals:


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What common seen animal models are associated with Ganglioside GD1?

There are no associated biomedical information in the current reference collection.

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All references with Ganglioside GD1

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Authors Title Published Journal PubMed Link
Benson MA et al. Unique ganglioside recognition strategies for clostridial neurotoxins. 2011 J. Biol. Chem. pmid:21849494
Zhang L et al. Ganglioside GD1a negatively regulates hepatocyte growth factor expression through caveolin-1 at the transcriptional level in murine osteosarcoma cells. 2011 Biochim. Biophys. Acta pmid:21554929
Yang HJ et al. Inhibition of ganglioside GD1a synthesis suppresses the differentiation of human mesenchymal stem cells into osteoblasts. 2011 Dev. Growth Differ. pmid:21492147
Simon O et al. Recurrent multiple cranial nerve palsy and anti-GD1a antibodies. 2011 Muscle Nerve pmid:21321960
Hatano K et al. Expression of gangliosides, GD1a, and sialyl paragloboside is regulated by NF-κB-dependent transcriptional control of α2,3-sialyltransferase I, II, and VI in human castration-resistant prostate cancer cells. 2011 Int. J. Cancer pmid:21165949
Bax M et al. Campylobacter jejuni lipooligosaccharides modulate dendritic cell-mediated T cell polarization in a sialic acid linkage-dependent manner. 2011 Infect. Immun. pmid:21502591
Del Favero E et al. Nanoscale structural response of ganglioside-containing aggregates to the interaction with sialidase. 2011 J. Neurochem. pmid:21214561
Lee HC et al. Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. 2012 J. Immunol. pmid:22956583
Venkateshwari S and Veluraja K Molecular Modelling and Molecular Dynamics studies of GD1A, GD1B and their complexes with BoNT/B--perspectives in interaction and specificity. 2012 J. Struct. Biol. pmid:22929125
Sturgill ER et al. Biosynthesis of the major brain gangliosides GD1a and GT1b. 2012 Glycobiology pmid:22735313