Ganglioside GD1

Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.

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Introduction

To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GD1?

Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GD1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GD1?

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What functions are associated with Ganglioside GD1?


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What lipids are associated with Ganglioside GD1?

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What genes are associated with Ganglioside GD1?

Related references are published most in these journals:


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What common seen animal models are associated with Ganglioside GD1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GD1

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Authors Title Published Journal PubMed Link
Mikhailenko IA et al. Interaction of low-density lipoproteins with gangliosides. 1991 Biochim. Biophys. Acta pmid:1911863
Suzuki Y et al. Gangliosides in the blood plasma: levels of ganglio-series gangliosides in the plasma after administration of brain gangliosides. 1988 Biochim. Biophys. Acta pmid:3048415
Fidelio GD et al. Molecular parameters and physical state of neutral glycosphingolipids and gangliosides in monolayers at different temperatures. 1986 Biochim. Biophys. Acta pmid:3942728
Peters MW et al. Evidence of a distribution difference between two gangliosides in bilayer membranes. 1984 Biochim. Biophys. Acta pmid:6548930
Heredia V et al. Interfacial stabilization of the antitumoral drug Paclitaxel in monolayers of GM1 and GD1a gangliosides. 2015 Biochim. Biophys. Acta pmid:26119566
Rosales Fritz VM et al. Chinese hamster ovary cells lacking GM1 and GD1a synthesize gangliosides upon transfection with human GM2 synthase. 1997 Biochim. Biophys. Acta pmid:9396632
Heffer-Lauc M et al. Membrane redistribution of gangliosides and glycosylphosphatidylinositol-anchored proteins in brain tissue sections under conditions of lipid raft isolation. 2005 Biochim. Biophys. Acta pmid:15629689
Tatsumi K et al. Enhanced expression of a-series gangliosides in fibroblasts of patients with peroxisome biogenesis disorders. 2001 Biochim. Biophys. Acta pmid:11278168
Rapoport E et al. Ganglioside binding pattern of CD33-related siglecs. 2003 Bioorg. Med. Chem. Lett. pmid:12639556
Hirai M and Takizawa T Intensive extrusion and occlusion of water in ganglioside micelles with thermal reversibility. 1998 Biophys. J. pmid:9635755
Hirai M et al. Interaction of gangliosides with proteins depending on oligosaccharide chain and protein surface modification. 1998 Biophys. J. pmid:9512034
McDaniel RV et al. Electrokinetic and electrostatic properties of bilayers containing gangliosides GM1, GD1a, or GT1. Comparison with a nonlinear theory. 1986 Biophys. J. pmid:3697476
Poppe L et al. Carbohydrate dynamics at a micellar surface: GD1a headgroup transformations revealed by NMR spectroscopy. 1994 Biophys. J. pmid:8061213
Inagaki M et al. Effects of ganglioside GD1a on the fluidity and phase transition of phosphatidylcholine model membrane immobilized on porous cellulose acetate filter. 1996 Biosci. Biotechnol. Biochem. pmid:8988630
Rocheleau JV and Petersen NO Sendai virus binds to a dispersed population of NBD-GD1a. 2000 Biosci. Rep. pmid:11095114
McGonigal R et al. Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. 2010 Brain pmid:20513658
Lopez PH et al. Structural requirements of anti-GD1a antibodies determine their target specificity. 2008 Brain pmid:18487279
Gong Y et al. Localization of major gangliosides in the PNS: implications for immune neuropathies. 2002 Brain pmid:12390975
Park JY et al. GM1 induces p38 and microtubule dependent ramification of rat primary microglia in vitro. 2008 Brain Res. pmid:18930716
Kotani M et al. Developmental changes of ganglioside expressions in postnatal rat cerebellar cortex. 1995 Brain Res. pmid:8624728