Ganglioside GD1

Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.

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Introduction

To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GD1?

Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GD1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GD1?

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What functions are associated with Ganglioside GD1?


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What lipids are associated with Ganglioside GD1?

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What genes are associated with Ganglioside GD1?

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What common seen animal models are associated with Ganglioside GD1?

There are no associated biomedical information in the current reference collection.

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All references with Ganglioside GD1

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Authors Title Published Journal PubMed Link
Sung CC et al. Gangliosides as diagnostic markers of human astrocytomas and primitive neuroectodermal tumors. 1994 Cancer pmid:7954264
Perillo MA et al. Modulation by gangliosides of the lamellar-inverted micelle (hexagonal II) phase transition in mixtures containing phosphatidylethanolamine and dioleoylglycerol. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:7937830
Acquotti D et al. Geometrical and conformational properties of ganglioside GalNAc-GD1a, IV4GalNAcIV3Neu5AcII3Neu5AcGgOse4Cer. 1994 Eur. J. Biochem. pmid:7925447
van Gorkom LC et al. Ganglioside GD1a generates domains of high curvature in phosphatidylethanolamine liposomes as determined by solid state 31P-NMR spectroscopy. 1995 Chem. Phys. Lipids pmid:7788794
Nishinaka T et al. Anti-ganglioside GD1a monoclonal antibody recognizes senile plaques in the brains of patients with Alzheimer-type dementia. 1993 Neurosci. Res. pmid:7694209
Brocca P et al. Aggregation properties of semisynthetic GD1a ganglioside (IV3Neu5AcII3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety. 1995 Chem. Phys. Lipids pmid:7586091
Nakayama J et al. Differential cell- and immuno-biological properties of murine B16-F1 and F10 melanomas: oncogene c-fos expression, sensitivity to LAK cells and/or IL-2, and components of gangliosides. 1995 J. Dermatol. pmid:7560451
Yuki N et al. Penner's serotype 4 of Campylobacter jejuni has a lipopolysaccharide that bears a GM1 ganglioside epitope as well as one that bears a GD1 a epitope. 1994 Infect. Immun. pmid:7513313
Coulon-Morelec MJ and Buc-Caron MH Lipid patterns of embryonal carcinoma cell lines and their derivatives: changes with differentiation. 1981 Dev. Biol. pmid:7239013
Scheel G et al. Model for the interaction of membrane-bound substrates and enzymes. Hydrolysis of ganglioside GD1a by sialidase of neuronal membranes isolated from calf brain. 1982 Eur. J. Biochem. pmid:7140766
Sarkar CP and Cenedella RJ Gangliosides in normal and cataractous lenses of several species. 1982 Biochim. Biophys. Acta pmid:7104379
Riedl M et al. A ganglioside-dependent cellular binding mechanism in rat macrophages. 1982 J. Immunol. pmid:7073871
Hinz HJ et al. Influence of gangliosides GM1 and GD1a on structural and thermotropic properties of sonicated small 1,2-dipalmitoyl-L-alpha-phosphatidylcholine vesicles. 1981 Biochim. Biophys. Acta pmid:6894700
Seyfried TN et al. Cellular localization of gangliosides in the developing mouse cerebellum: analysis using the weaver mutant. 1983 J. Neurochem. pmid:6875549
Sonnino S et al. High performance liquid chromatography preparation of the molecular species of GM1 and GD1a gangliosides with homogeneous long chain base composition. 1984 J. Lipid Res. pmid:6747465
Sebille A Nerve regeneration in exogenous cerebral ganglioside-treated rats. 1984 Muscle Nerve pmid:6727911
Spirman N et al. Regenerative capacity of the goldfish visual system is affected by antibodies specific to gangliosides injected intraocularly. 1984 J. Neuroimmunol. pmid:6725551
Hashimoto Y et al. Expression of GM1 and GD1a in liver of wild mice. 1984 J. Biochem. pmid:6706920
Hashimoto Y et al. Expression of GM1 and GD1a in mouse liver is linked to the H-2 complex on chromosome 17. 1983 J. Biochem. pmid:6671979
Peters MW et al. Evidence of a distribution difference between two gangliosides in bilayer membranes. 1984 Biochim. Biophys. Acta pmid:6548930