Ganglioside GD1

Ganglioside GD1 is a lipid of Sphingolipids (SP) class. Ganglioside gd1 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Neuritis, Motor, Autoimmune Syndrome Type II, Polyglandular and protrusion. The involved functions are known as Drug Interactions, inhibitors, Signal Transduction, Baresthesia and Biological function, NOS. Ganglioside gd1 often locates in Membrane, nucleocapsid location, Cell membrane, Cell surface and Face. The associated genes with Ganglioside GD1 are Polypeptides, N-dodecyl-L-lysine amide, anti-IgM, VIP gene and Homologous Gene. The related lipids are sialogangliosides, ganglioside, GD1b, GT1b-ganglioside, ganglioside, GD1a and IV(4)-galactosyl-N-acetylganglioside GD1a.

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Introduction

To understand associated biological information of Ganglioside GD1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GD1?

Ganglioside GD1 is suspected in Neuropathy, Sensory neuropathy, Acute motor neuropathy, Virus Diseases, Cholera, Little's Disease and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GD1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GD1?

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What functions are associated with Ganglioside GD1?


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What lipids are associated with Ganglioside GD1?

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What genes are associated with Ganglioside GD1?

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What common seen animal models are associated with Ganglioside GD1?

There are no associated biomedical information in the current reference collection.

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All references with Ganglioside GD1

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Authors Title Published Journal PubMed Link
Ladisch S and Wu ZL Detection of a tumour-associated ganglioside in plasma of patients with neuroblastoma. 1985 Lancet pmid:2857215
Qin J et al. GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis. 2017 J. Neurosci. pmid:28899916
Pestronk A et al. Patterns of serum IgM antibodies to GM1 and GD1a gangliosides in amyotrophic lateral sclerosis. 1989 Ann. Neurol. pmid:2913936
Bianco ID et al. Modulation of phospholipase A2 activity by neutral and anionic glycosphingolipids in monolayers. 1989 Biochem. J. pmid:2930519
Suzuki Y et al. Gangliosides in the blood plasma: levels of ganglio-series gangliosides in the plasma after administration of brain gangliosides. 1988 Biochim. Biophys. Acta pmid:3048415
Zeigler M and Bach G Internalization of exogenous gangliosides in cultured skin fibroblasts for the diagnosis of mucolipidosis IV. 1986 Clin. Chim. Acta pmid:3087662
Pohlentz G et al. Both GA2, GM2, and GD2 synthases and GM1b, GD1a, and GT1b synthases are single enzymes in Golgi vesicles from rat liver. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3140234
Taki T et al. Appearance of a novel type of ganglioside (GD1 alpha) in a differentiation-resistant clone of mouse myeloid leukemia cells, M1-R1. 1988 Cell Struct. Funct. pmid:3163528
Watanabe Y et al. Effect of gangliosides on murine megakaryocytopoiesis in a liquid culture system. 1988 Cell Struct. Funct. pmid:3180256
Wu GS and Ledeen R Quantification of gangliotetraose gangliosides with cholera toxin. 1988 Anal. Biochem. pmid:3189815
Fronza G et al. Synthesis and structural characterization of the dilactone derivative of GD1a ganglioside. 1988 Carbohydr. Res. pmid:3242802
Jeng KC et al. Gangliosides suppression of murine lymphoproliferation and interleukin 1 production. 1988 Immunol. Lett. pmid:3266614
Sbaschnig-Agler M et al. Gangliosides and other lipids of the growth cone membrane. 1988 J. Neurochem. pmid:3379405
Schengrund CL and Prouty C Oligosaccharide portion of GM1 enhances process formation by S20Y neuroblastoma cells. 1988 J. Neurochem. pmid:3379408
Nakamura Y et al. Age-dependent changes in GM1 and GD1a expression in mouse liver. 1988 J. Biochem. pmid:3391992
Willibald CJ et al. Axonal transport of intraocularly injected [3H-Sph]-GD1a in the chicken optic system and the fate of the exogenous ganglioside distributed by blood. 1988 Neurosci. Res. pmid:3399144
Venerando B et al. Interactions of pig brain cytosolic sialidase with gangliosides. The formation of catalytically inactive enzyme-ganglioside complexes requires homogeneous ganglioside micelles and is a reversible phenomenon. 1987 J. Biochem. pmid:3436965
Beitinger H et al. Influence of Ca2+ and temperature on the interaction of gangliosides with valinomycin in mixed monolayers at the air/water interface. 1987 J. Biochem. pmid:3436968
Matyas GR et al. Alteration of glycolipids in ras-transfected NIH 3T3 cells. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:3476926
Murayama K et al. Qualitative differences in position of sialylation and surface expression of glycolipids between murine lymphomas with low metastatic (Eb) and high metastatic (ESb) potentials and isolation of a novel disialoganglioside (GD1 alpha) from Eb cells. 1986 Cancer Res. pmid:3484680