| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Kanda N and Tamaki K | Ganglioside GT1b suppresses immunoglobulin production by human peripheral blood mononuclear cells. | 1999 | Immunology | pmid:10233751 |
| Kozaki S | [Studies on the receptor for Clostridium botulinum neurotoxin]. | 1999 | Nippon Saikingaku Zasshi | pmid:10356952 |
| Caudie C et al. | [Measurement of antiganglioside autoantibodies by immunodot-blot assay: clinical importance in peripheral neuropathies]. | Ann. Biol. Clin. (Paris) | pmid:10518060 | |
| Morano S et al. | Autoimmune markers and neurological complications in non-insulin-dependent diabetes mellitus. | 1999 | Hum. Immunol. | pmid:10527392 |
| Gilbert M et al. | Biosynthesis of ganglioside mimics in Campylobacter jejuni OH4384. Identification of the glycosyltransferase genes, enzymatic synthesis of model compounds, and characterization of nanomole amounts by 600-mhz (1)h and (13)c NMR analysis. | 2000 | J. Biol. Chem. | pmid:10660542 |
| Aydin M et al. | Age-related changes in GM1, GD1a, GT1b components of gangliosides in Wistar albino rats. | 2000 | Cell Biochem. Funct. | pmid:10686582 |
| Kotani M et al. | Ganglioside GT1b in rat brain binds to p58, a brain-specific sodium-dependent inorganic phosphate cotransporter: expression cloning with a specific monoclonal antibody to ganglioside GT1b-binding protein. | 2000 | J. Biochem. | pmid:10731661 |
| Kukimoto M et al. | Crystallization and preliminary X-ray diffraction analysis of the extracellular domain of the cell surface antigen CD38 complexed with ganglioside. | 2000 | J. Biochem. | pmid:10731682 |
| Yoshino H et al. | IgG antiganglioside antibodies in Guillain-Barré syndrome with bulbar palsy. | 2000 | J. Neuroimmunol. | pmid:10742563 |
| Vautrin J et al. | Surface-accessible GABA supports tonic and quantal synaptic transmission. | 2000 | Synapse | pmid:10842350 |
| Fitzsimmons SP et al. | Inhibition of tetanus toxin fragment C binding to ganglioside G(T1b) by monoclonal antibodies recognizing different epitopes. | 2000 | Vaccine | pmid:10924793 |
| Sinha K et al. | Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties. | 2000 | Mol. Microbiol. | pmid:10972823 |
| Bukowski JF et al. | T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity. | 2000 | Eur. J. Immunol. | pmid:11093135 |
| Wang X et al. | Carbohydrate-carbohydrate binding of ganglioside to integrin alpha(5) modulates alpha(5)beta(1) function. | 2001 | J. Biol. Chem. | pmid:11118433 |
| Kanda N and Watanabe S | Gangliosides GD1b, GT1b, and GQ1b enhance IL-2 and IFN-gamma production and suppress IL-4 and IL-5 production in phytohemagglutinin-stimulated human T cells. | 2001 | J. Immunol. | pmid:11123278 |
| Hara-Yokoyama M et al. | Complex gangliosides as cell surface inhibitors for the ecto-NAD+ glycohydrolase of CD38. | 2001 | Biochemistry | pmid:11170409 |
| Metelmann W et al. | Nano-electrospray ionization time-of-flight mass spectrometry of gangliosides from human brain tissue. | 2001 | J Mass Spectrom | pmid:11180643 |
| Chung ES et al. | GT1b ganglioside induces death of dopaminergic neurons in rat mesencephalic cultures. | 2001 | Neuroreport | pmid:11234774 |
| Vinson M et al. | Myelin-associated glycoprotein interacts with ganglioside GT1b. A mechanism for neurite outgrowth inhibition. | 2001 | J. Biol. Chem. | pmid:11279053 |
| Fotinou C et al. | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. | 2001 | J. Biol. Chem. | pmid:11418600 |
| Mizutani K et al. | Sensorimotor demyelinating neuropathy with IgM antibody against gangliosides GD1a, GT1b and GM3. | 2001 | J. Neurol. Sci. | pmid:11489278 |
| Zuolo ML et al. | Identification of GM3 as a marker of therapy-resistant periradicular lesions. | 2001 | J Endod | pmid:11491632 |
| Kanda N et al. | Gangliosides GD1b, GT1b, and GQ1b suppress the growth of human melanoma by inhibiting interleukin-8 production: the inhibition of adenylate cyclase. | 2001 | J. Invest. Dermatol. | pmid:11511306 |
| Bieberich E et al. | Regulation of apoptosis during neuronal differentiation by ceramide and b-series complex gangliosides. | 2001 | J. Biol. Chem. | pmid:11574545 |
| Schnaar RL et al. | Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides. | 2002 | Anal. Biochem. | pmid:11878808 |
| Mirkin BL et al. | Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B. | 2002 | Cell Prolif. | pmid:11952645 |
| Alaedini A et al. | Detection of anti-ganglioside antibodies in Guillain-Barré syndrome and its variants by the agglutination assay. | 2002 | J. Neurol. Sci. | pmid:11959155 |
| Yamashita T et al. | The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho. | 2002 | J. Cell Biol. | pmid:12011108 |
| Woolf CJ and Bloechlinger S | Neuroscience. It takes more than two to Nogo. | 2002 | Science | pmid:12183616 |
| Irvine AD et al. | A colorimetric bead-binding assay for detection of intermolecular interactions. | 2002 | Exp. Dermatol. | pmid:12366700 |
| Caudie C et al. | [Antiganglioside autoantibody profiles in Guillain-Barré syndrome]. | Ann. Biol. Clin. (Paris) | pmid:12368145 | |
| Gong Y et al. | Localization of major gangliosides in the PNS: implications for immune neuropathies. | 2002 | Brain | pmid:12390975 |
| Onodera M et al. | Acute isolated bulbar palsy with anti-GT1a IgG antibody subsequent to Campylobacter jejuni enteritis. | 2002 | J. Neurol. Sci. | pmid:12409189 |
| Orr CF et al. | An inflammatory review of Parkinson's disease. | 2002 | Prog. Neurobiol. | pmid:12531233 |
| Colarow L et al. | Characterization and biological activity of gangliosides in buffalo milk. | 2003 | Biochim. Biophys. Acta | pmid:12573454 |
| Yamamoto HA and Mohanan PV | Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice. | 2003 | Brain Res. | pmid:12573517 |
| Osanai T et al. | Immunohistochemical and biochemical analyses of GD3, GT1b, and GQ1b gangliosides during neural differentiation of P19 EC cells. | 2003 | FEBS Lett. | pmid:12606034 |
| Rapoport E et al. | Ganglioside binding pattern of CD33-related siglecs. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12639556 |
| Yamamoto HA and Mohanan PV | In vivo and in vitro effects of melatonin or ganglioside GT1B on L-cysteine-induced brain mitochondrial DNA damage in mice. | 2003 | Toxicol. Sci. | pmid:12700404 |
| Wang XQ et al. | Ganglioside GM3 inhibits matrix metalloproteinase-9 activation and disrupts its association with integrin. | 2003 | J. Biol. Chem. | pmid:12724312 |
| Sugiyama N et al. | [High-dose intravenous immunoglobulin therapy in a child case of Bickerstaff's brainstem encephalitis]. | 2003 | No To Hattatsu | pmid:12875210 |
| Velly LJ et al. | Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: role of glutamate and its transporters. | 2003 | Anesthesiology | pmid:12883409 |
| Yoshino H et al. | Isolated bovine spinal motoneurons have specific ganglioside antigens recognized by sera from patients with motor neuron disease and motor neuropathy. | 1992 | J. Neurochem. | pmid:1383424 |
| Colville CA et al. | The interaction of tetanus toxin with intact bovine adrenal chromaffin cells: binding of toxin and subsequent inhibition of catecholamine release. | 1992 | Biochim. Biophys. Acta | pmid:1445928 |
| Hettmer S et al. | Biological stratification of human neuroblastoma by complex "B" pathway ganglioside expression. | 2003 | Cancer Res. | pmid:14612523 |
| Baksh MM et al. | Detection of molecular interactions at membrane surfaces through colloid phase transitions. | 2004 | Nature | pmid:14712272 |
| Higashi H and Chen NH | Ganglioside/protein kinase signals triggering cytoskeletal actin reorganization. | 2004 | Glycoconj. J. | pmid:14973370 |
| Mandal PK and Pettegrew JW | Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment. | 2004 | Neurochem. Res. | pmid:15002743 |
| Nagashima T et al. | Clinical correlates of serum anti-GT1a IgG antibodies. | 2004 | J. Neurol. Sci. | pmid:15050449 |
| Guan Z et al. | Gangliosides inhibit platelet-derived growth-factor-stimulated increases in intracellular calcium in Swiss 3T3 cells. | 1992 | Biochim. Biophys. Acta | pmid:1520706 |
| Yowler BC and Schengrund CL | Botulinum neurotoxin A changes conformation upon binding to ganglioside GT1b. | 2004 | Biochemistry | pmid:15274627 |
| Freire E et al. | Sialic acid residues on astrocytes regulate neuritogenesis by controlling the assembly of laminin matrices. | 2004 | J. Cell. Sci. | pmid:15292398 |
| Yuki N et al. | Acute relapsing sensory neuropathy associated with IgM antibody against B-series gangliosides containing a GalNAc beta 1-4(Gal3-2 alpha NeuAc8-2 alpha NeuAc)beta 1 configuration. | 1992 | Neurology | pmid:1549241 |
| Müthing J et al. | Tumor-associated CD75s gangliosides and CD75s-bearing glycoproteins with Neu5Acalpha2-6Galbeta1-4GlcNAc-residues are receptors for the anticancer drug rViscumin. | 2005 | FASEB J. | pmid:15520251 |
| Vukelić Z et al. | Screening and sequencing of complex sialylated and sulfated glycosphingolipid mixtures by negative ion electrospray Fourier transform ion cyclotron resonance mass spectrometry. | 2005 | J. Am. Soc. Mass Spectrom. | pmid:15792727 |
| Wang XQ et al. | Gangliosides inhibit urokinase-type plasminogen activator (uPA)-dependent squamous carcinoma cell migration by preventing uPA receptor/alphabeta integrin/epidermal growth factor receptor interactions. | 2005 | J. Invest. Dermatol. | pmid:15816844 |
| Hettmer S et al. | Low complex ganglioside expression characterizes human neuroblastoma cell lines. | 2005 | Cancer Lett. | pmid:15922866 |
| Boffey J et al. | Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire. | 2005 | J. Neuroimmunol. | pmid:15967512 |
| Yamaji K et al. | [Internal ophthalmoplegia in acute oropharyngeal palsy with anti-GQ1b and anti-GT1a IgG antibodies]. | 2005 | No To Shinkei | pmid:16026049 |
| Jayaraman S et al. | Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin. | 2005 | Proteins | pmid:16104015 |
| Gavella M et al. | Trisialoganglioside GT1b prevents increase in sperm membrane molecular ordering induced by in vitro lipid peroxidation. | J. Androl. | pmid:16291967 | |
| Murakami N et al. | An adolescent with pharyngeal-cervical-brachial variant of Guillain-Barré syndrome after cytomegalovirus infection. | 2006 | Brain Dev. | pmid:16368212 |
| Low JA et al. | Identification of gangliosides GD1b and GT1b as receptors for BK virus. | 2006 | J. Virol. | pmid:16415013 |
| Samiee KT et al. | Zero mode waveguides for single-molecule spectroscopy on lipid membranes. | 2006 | Biophys. J. | pmid:16461393 |
| Wada Y et al. | [A case of acute oropharyngeal palsy with nasal voice as main symptom]. | 2006 | No To Shinkei | pmid:16629449 |
| Jou I et al. | Gangliosides trigger inflammatory responses via TLR4 in brain glia. | 2006 | Am. J. Pathol. | pmid:16651628 |
| Rojas-Garcia R et al. | A novel antiganglioside specificity against terminal NeuNAc(alfa 2-3)Gal in acute bulbar palsy. | 2006 | J. Neuroimmunol. | pmid:16707165 |
| Attrill H et al. | Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b. | 2006 | J. Biol. Chem. | pmid:16895906 |
| Slade AL et al. | In situ scanning probe microscopy studies of tetanus toxin-membrane interactions. | 2006 | Biophys. J. | pmid:16997879 |
| Kaida K et al. | Anti-ganglioside complex antibodies associated with severe disability in GBS. | 2007 | J. Neuroimmunol. | pmid:17113161 |
| Kohda T et al. | Differential contribution of the residues in C-terminal half of the heavy chain of botulinum neurotoxin type B to its binding to the ganglioside GT1b and the synaptotagmin 2/GT1b complex. | Microb. Pathog. | pmid:17188834 | |
| Baldwin MR et al. | Botulinum neurotoxin B-host receptor recognition: it takes two receptors to tango. | 2007 | Nat. Struct. Mol. Biol. | pmid:17203068 |
| Peng YF et al. | Development of a large scale process for the conversion of polysialogangliosides to monosialotetrahexosylganglioside with a novel strain of Brevibacterium casei producing sialidase. | 2007 | Biotechnol. Lett. | pmid:17415532 |
| Lee DH et al. | Effects of daunorubicin on ganglioside expression and neuronal differentiation of mouse embryonic stem cells. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17707770 |
| Matusica D et al. | Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking. | 2008 | J. Neurosci. Res. | pmid:17896795 |
| Couesnon A et al. | Receptor-mediated transcytosis of botulinum neurotoxin A through intestinal cell monolayers. | 2008 | Cell. Microbiol. | pmid:17900298 |
| Baldwin MR et al. | Subunit vaccine against the seven serotypes of botulism. | 2008 | Infect. Immun. | pmid:18070903 |
| Zhang H et al. | Ganglioside GM1 binding the N-terminus of amyloid precursor protein. | 2009 | Neurobiol. Aging | pmid:18077059 |
| Kim BH et al. | Expression of ganglioside GT1b in mouse embryos at different developmental stages after cryopreservation. | 2008 | Arch. Pharm. Res. | pmid:18277613 |
| Williams G et al. | Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. | 2008 | J. Biol. Chem. | pmid:18411262 |
| Miller CE et al. | Integration of ganglioside GT1b receptor into DPPE and DPPC phospholipid monolayers: an X-ray reflectivity and grazing-incidence diffraction study. | 2008 | Biophys. J. | pmid:18599631 |
| Schengrund CL et al. | Binding of botulinum and tetanus neurotoxins to ganglioside GT1b and derivatives thereof. | 1991 | J. Neurochem. | pmid:1861141 |
| Townson KH et al. | Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury. | 2008 | J. Neuroimmunol. | pmid:18684516 |
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Ganglioside GT1
Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.
Cross Reference
Introduction
To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ganglioside GT1?
Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ganglioside GT1
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ganglioside GT1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ganglioside GT1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ganglioside GT1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ganglioside GT1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ganglioside GT1?
There are no associated biomedical information in the current reference collection.