Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

Cross Reference

Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

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What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
pmid:
Jou I et al. Gangliosides trigger inflammatory responses via TLR4 in brain glia. 2006 Am. J. Pathol. pmid:16651628
Wu GS and Ledeen R Quantification of gangliotetraose gangliosides with cholera toxin. 1988 Anal. Biochem. pmid:3189815
Schnaar RL et al. Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides. 2002 Anal. Biochem. pmid:11878808
Velly LJ et al. Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: role of glutamate and its transporters. 2003 Anesthesiology pmid:12883409
Caudie C et al. [Antiganglioside autoantibody profiles in Guillain-Barré syndrome]. Ann. Biol. Clin. (Paris) pmid:12368145
Caudie C et al. [Measurement of antiganglioside autoantibodies by immunodot-blot assay: clinical importance in peripheral neuropathies]. Ann. Biol. Clin. (Paris) pmid:10518060
Fukano Y and Ito M Preparation of GM1 ganglioside with sialidase-producing marine bacteria as a microbial biocatalyst. 1997 Appl. Environ. Microbiol. pmid:9143118
Kim BH et al. Expression of ganglioside GT1b in mouse embryos at different developmental stages after cryopreservation. 2008 Arch. Pharm. Res. pmid:18277613
Kato E et al. Interaction between ganglioside-containing liposome and rat T-lymphocyte: confocal fluorescence microscopic study. 1994 Biochem. Biophys. Res. Commun. pmid:7945325
Chan KF Phosphorylation of myelin basic protein and peptides by ganglioside-stimulated protein kinase. 1989 Biochem. Biophys. Res. Commun. pmid:2480129
Whitemarsh RC et al. Model for studying Clostridium botulinum neurotoxin using differentiated motor neuron-like NG108-15 cells. 2012 Biochem. Biophys. Res. Commun. pmid:23000406
Lee DH et al. Effects of daunorubicin on ganglioside expression and neuronal differentiation of mouse embryonic stem cells. 2007 Biochem. Biophys. Res. Commun. pmid:17707770
Bianco ID et al. Modulation of phospholipase A2 activity by neutral and anionic glycosphingolipids in monolayers. 1989 Biochem. J. pmid:2930519
Hara-Yokoyama M et al. Complex gangliosides as cell surface inhibitors for the ecto-NAD+ glycohydrolase of CD38. 2001 Biochemistry pmid:11170409
Yowler BC and Schengrund CL Botulinum neurotoxin A changes conformation upon binding to ganglioside GT1b. 2004 Biochemistry pmid:15274627
Palestini P et al. Change of ganglioside accessibility at the plasma membrane surface of cultured neurons, following protein kinase C activation. 1998 Biochemistry pmid:9485467
Willjes G et al. Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity. 2013 Biochemistry pmid:23647335
Chandrasekaran EV et al. Mammalian sialyltransferase ST3Gal-II: its exchange sialylation catalytic properties allow labeling of sialyl residues in mucin-type sialylated glycoproteins and specific gangliosides. 2011 Biochemistry pmid:21913655
Sun S et al. Botulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pH. 2012 Biochemistry pmid:22720883