Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

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Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

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What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

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All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Hamasaki H et al. GT1b in human metastatic brain tumors: GT1b as a brain metastasis-associated ganglioside. 1999 Biochim. Biophys. Acta pmid:9931455
Nordin V et al. Gangliosides in cerebrospinal fluid in children with autism spectrum disorders. 1998 Dev Med Child Neurol pmid:9766735
Kozaki S et al. Ganglioside GT1b as a complementary receptor component for Clostridium botulinum neurotoxins. 1998 Microb. Pathog. pmid:9712688
Letinić K et al. C-pathway polysialogangliosides are transiently expressed in the human cerebrum during fetal development. 1998 Neuroscience pmid:9692737
Koga M et al. Is IgG anti-GT1a antibody associated with pharyngeal-cervical-brachial weakness or oropharyngeal palsy in Guillain-Barré syndrome? 1998 J. Neuroimmunol. pmid:9655474
Heffer-Lauc M et al. C-series polysialogangliosides are expressed on stellate neurons of adult human cerebellum. 1998 Glycoconj. J. pmid:9613831
Zhou J et al. Gangliosides enhance apoptosis of thymocytes. 1998 Cell. Immunol. pmid:9606992
Ilyas AA et al. Antibodies to GT1a ganglioside in patients with Guillain-Barré syndrome. 1998 J. Neuroimmunol. pmid:9585812
Hashimoto Y et al. A streptavidin-based neoglycoprotein carrying more than 140 GT1b oligosaccharides: quantitative estimation of the binding specificity of murine sialoadhesin expressed on CHO cells. 1998 J. Biochem. pmid:9538230
Sung CC et al. Integrin alpha 5 beta 1 expression is required for inhibition of keratinocyte migration by ganglioside GT1b. 1998 Exp. Cell Res. pmid:9521848
Palestini P et al. Change of ganglioside accessibility at the plasma membrane surface of cultured neurons, following protein kinase C activation. 1998 Biochemistry pmid:9485467
Winter A et al. Gangliosides in phospholipid bilayer membranes: interaction with tetanus toxin. 1996 Chem. Phys. Lipids pmid:9450318
Mizoguchi K et al. Anti-GQ1b and anti-GT1a IgG antibodies in a patient with acute demyelinating polyradiculoneuropathy without ophthalmoplegia. 1997 J. Neurol. Neurosurg. Psychiatry pmid:9328270
Velasco I and Tapia R Ruthenium red neurotoxicity and interaction with gangliosides in primary cortical cultures. 1997 J. Neurosci. Res. pmid:9211991
Fukano Y and Ito M Preparation of GM1 ganglioside with sialidase-producing marine bacteria as a microbial biocatalyst. 1997 Appl. Environ. Microbiol. pmid:9143118
Hynds DL et al. Gangliosides inhibit growth factor-stimulated neurite outgrowth in SH-SY5Y human neuroblastoma cells. 1997 J. Neurosci. Res. pmid:9089210
Zaprianova E et al. Ganglioside spinal cord changes in chronic relapsing experimental allergic encephalomyelitis induced in the Lewis rats. 1997 Neurochem. Res. pmid:9016843
Katoh N and Miyamoto T Enhancement by ganglioside GT1b of annexin I phosphorylation in bovine mammary gland in the presence of phosphatidylserine and Ca2+. 1996 Lipids pmid:8882979
Massa PT and Wu C Modulation of major histocompatibility complex class I genes by interferon-gamma and ganglioside GT 1b in astrocytes: involvement of protein tyrosine phosphatases. 1996 J. Neurochem. pmid:8863487
Hann RM et al. Gangliosides in membranes from Torpedo electric organ. 1996 Lipids pmid:8784743