Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

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Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Gavella M et al. Trisialoganglioside GT1b prevents increase in sperm membrane molecular ordering induced by in vitro lipid peroxidation. J. Androl. pmid:16291967
Izumi T et al. Normal developmental profiles of CSF gangliotetraose-series gangliosides from neonatal period to adolescence. Pediatr. Neurol. pmid:8216543
Izumi T et al. Low levels of CSF gangliotetraose-series gangliosides in West syndrome: implication of brain maturation disturbance. Pediatr. Neurol. pmid:8216542
Caudie C et al. [Antiganglioside autoantibody profiles in Guillain-Barré syndrome]. Ann. Biol. Clin. (Paris) pmid:12368145
Nishikawa H and Kitani S Inhibitory effect of ganglioside on mastoparan-induced cytotoxicity and degranulation in lipid raft of connective tissue type mast cell. J. Biochem. Mol. Toxicol. pmid:21671308
pmid:
Caudie C et al. [Measurement of antiganglioside autoantibodies by immunodot-blot assay: clinical importance in peripheral neuropathies]. Ann. Biol. Clin. (Paris) pmid:10518060
Kohda T et al. Differential contribution of the residues in C-terminal half of the heavy chain of botulinum neurotoxin type B to its binding to the ganglioside GT1b and the synaptotagmin 2/GT1b complex. Microb. Pathog. pmid:17188834
Bertoli E et al. Electron paramagnetic resonance studies on the fluidity and surface dynamics of egg phosphatidylcholine vesicles containing gangliosides. 1981 Biochim. Biophys. Acta pmid:6271209
Rauvala H et al. Studies on cell adhesion and recognition. I. Extent and specificity of cell adhesion triggered by carbohydrate-reactive proteins (glycosidases and lectins) and by fibronectin. 1981 J. Cell Biol. pmid:6782107
Sarkar CP and Cenedella RJ Gangliosides in normal and cataractous lenses of several species. 1982 Biochim. Biophys. Acta pmid:7104379
Seyfried TN et al. Cellular localization of gangliosides in the developing mouse cerebellum: analysis using the weaver mutant. 1983 J. Neurochem. pmid:6875549
Seyfried TN et al. Cellular distribution of gangliosides in the developing mouse cerebellum: analysis using the staggerer mutant. 1984 J. Neurochem. pmid:6470710
Mestrallet MG et al. Tryptophan fluorescence properties of cholera toxin upon interacting with ganglioside GD1b. 1984 J. Neurosci. Res. pmid:6502757
Spirman N et al. Regenerative capacity of the goldfish visual system is affected by antibodies specific to gangliosides injected intraocularly. 1984 J. Neuroimmunol. pmid:6725551
Leskawa KC and Hogan EL Quantitation of the in vitro neuroblastoma response to exogenous, purified gangliosides. 1985 J. Neurosci. Res. pmid:4009744
Slepushkin VA et al. Action of influenza virus neuraminidase on gangliosides. Haemagglutinin inhibits viral neuraminidase. 1985 FEBS Lett. pmid:3979549
Ladisch S and Wu ZL Detection of a tumour-associated ganglioside in plasma of patients with neuroblastoma. 1985 Lancet pmid:2857215
Basu A and Glew RH Characterization of the activation of rat liver beta-glucosidase by sialosylgangliotetraosylceramide. 1985 J. Biol. Chem. pmid:3932339
Goldenring JR et al. Calcium/ganglioside-dependent protein kinase activity in rat brain membrane. 1985 J. Neurochem. pmid:2579206