Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

Cross Reference

Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Velly LJ et al. Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: role of glutamate and its transporters. 2003 Anesthesiology pmid:12883409
Higashi H and Chen NH Ganglioside/protein kinase signals triggering cytoskeletal actin reorganization. 2004 Glycoconj. J. pmid:14973370
Yowler BC and Schengrund CL Botulinum neurotoxin A changes conformation upon binding to ganglioside GT1b. 2004 Biochemistry pmid:15274627
Baksh MM et al. Detection of molecular interactions at membrane surfaces through colloid phase transitions. 2004 Nature pmid:14712272
Freire E et al. Sialic acid residues on astrocytes regulate neuritogenesis by controlling the assembly of laminin matrices. 2004 J. Cell. Sci. pmid:15292398
Mandal PK and Pettegrew JW Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment. 2004 Neurochem. Res. pmid:15002743
Nagashima T et al. Clinical correlates of serum anti-GT1a IgG antibodies. 2004 J. Neurol. Sci. pmid:15050449
Boffey J et al. Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire. 2005 J. Neuroimmunol. pmid:15967512
Jayaraman S et al. Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin. 2005 Proteins pmid:16104015
Yamaji K et al. [Internal ophthalmoplegia in acute oropharyngeal palsy with anti-GQ1b and anti-GT1a IgG antibodies]. 2005 No To Shinkei pmid:16026049