Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

Cross Reference

Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Kozaki S et al. Ganglioside GT1b as a complementary receptor component for Clostridium botulinum neurotoxins. 1998 Microb. Pathog. pmid:9712688
Kohda T et al. Differential contribution of the residues in C-terminal half of the heavy chain of botulinum neurotoxin type B to its binding to the ganglioside GT1b and the synaptotagmin 2/GT1b complex. Microb. Pathog. pmid:17188834
Sinha K et al. Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties. 2000 Mol. Microbiol. pmid:10972823
Zheng Y et al. Efficient biotransformation of polysialogangliosides for preparation of GM1 by Cellulosimicrobium sp. 21. 2014 Molecules pmid:25299818
Khalili E et al. Production of Recombinant Human scFv Against Tetanus Toxin Heavy Chain by Phage Display Technology. 2015 Monoclon Antib Immunodiagn Immunother pmid:26492617
Baldwin MR et al. Botulinum neurotoxin B-host receptor recognition: it takes two receptors to tango. 2007 Nat. Struct. Mol. Biol. pmid:17203068
Baksh MM et al. Detection of molecular interactions at membrane surfaces through colloid phase transitions. 2004 Nature pmid:14712272
Zhang H et al. Ganglioside GM1 binding the N-terminus of amyloid precursor protein. 2009 Neurobiol. Aging pmid:18077059
Zaprianova E et al. Ganglioside spinal cord changes in chronic relapsing experimental allergic encephalomyelitis induced in the Lewis rats. 1997 Neurochem. Res. pmid:9016843
Mandal PK and Pettegrew JW Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment. 2004 Neurochem. Res. pmid:15002743