Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

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Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

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What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

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All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Slepushkin VA et al. Interaction of influenza virus with gangliosides and liposomes containing gangliosides. 1988 Eur. J. Biochem. pmid:3371350
Bukowski JF et al. T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity. 2000 Eur. J. Immunol. pmid:11093135
Sung CC et al. Integrin alpha 5 beta 1 expression is required for inhibition of keratinocyte migration by ganglioside GT1b. 1998 Exp. Cell Res. pmid:9521848
Paller AS et al. Ganglioside GT1b induces keratinocyte differentiation without activating protein kinase C. 1995 Exp. Cell Res. pmid:7867710
Irvine AD et al. A colorimetric bead-binding assay for detection of intermolecular interactions. 2002 Exp. Dermatol. pmid:12366700
Müthing J et al. Tumor-associated CD75s gangliosides and CD75s-bearing glycoproteins with Neu5Acalpha2-6Galbeta1-4GlcNAc-residues are receptors for the anticancer drug rViscumin. 2005 FASEB J. pmid:15520251
Takamizawa K et al. TLC immunostaining characterization of Clostridium botulinum type A neurotoxin binding to gangliosides and free fatty acids. 1986 FEBS Lett. pmid:3709810
Irie F et al. Biosynthetic pathway for a new series of gangliosides, GT1a alpha and GQ1b alpha. 1994 FEBS Lett. pmid:8082783
Schifferer F et al. Effect of calcium and temperature on mixed lipid-valinomycin monolayers. A comparison of glycosphingolipids (ganglioside GT1b, sulphatides) and phosphatidylcholine. 1988 FEBS Lett. pmid:3384088
Slepushkin VA et al. Action of influenza virus neuraminidase on gangliosides. Haemagglutinin inhibits viral neuraminidase. 1985 FEBS Lett. pmid:3979549
Osanai T et al. Immunohistochemical and biochemical analyses of GD3, GT1b, and GQ1b gangliosides during neural differentiation of P19 EC cells. 2003 FEBS Lett. pmid:12606034
Nishiki T et al. The high-affinity binding of Clostridium botulinum type B neurotoxin to synaptotagmin II associated with gangliosides GT1b/GD1a. 1996 FEBS Lett. pmid:8557112
Hwang YH et al. Synthesis of 2-deoxy-D-galactose containing gangliosides in vivo. 1993 FEBS Lett. pmid:8335096
Raimondi F et al. Calcium-dependent intestinal chloride secretion by Vibrio parahaemolyticus thermostable direct hemolysin in a rabbit model. 1995 Gastroenterology pmid:7615186
Hicks D et al. Stimulation of endogenous ganglioside metabolism by neurotrophic growth factors in cultured retinal Müller glia. 1996 Glia pmid:8721672
Heffer-Lauc M et al. C-series polysialogangliosides are expressed on stellate neurons of adult human cerebellum. 1998 Glycoconj. J. pmid:9613831
Higashi H and Chen NH Ganglioside/protein kinase signals triggering cytoskeletal actin reorganization. 2004 Glycoconj. J. pmid:14973370
Yousefi M et al. Comparative in vitro and in vivo assessment of toxin neutralization by anti-tetanus toxin monoclonal antibodies. 2014 Hum Vaccin Immunother pmid:24126015
Morano S et al. Autoimmune markers and neurological complications in non-insulin-dependent diabetes mellitus. 1999 Hum. Immunol. pmid:10527392
Yu R et al. Enhanced expression of soluble recombinant tetanus neurotoxin Hc in Escherichia coli as a tetanus vaccine candidate. 2011 Immunobiology pmid:20888666