Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

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Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

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All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Samiee KT et al. Zero mode waveguides for single-molecule spectroscopy on lipid membranes. 2006 Biophys. J. pmid:16461393
Jou I et al. Gangliosides trigger inflammatory responses via TLR4 in brain glia. 2006 Am. J. Pathol. pmid:16651628
Rojas-Garcia R et al. A novel antiganglioside specificity against terminal NeuNAc(alfa 2-3)Gal in acute bulbar palsy. 2006 J. Neuroimmunol. pmid:16707165
Wada Y et al. [A case of acute oropharyngeal palsy with nasal voice as main symptom]. 2006 No To Shinkei pmid:16629449
Low JA et al. Identification of gangliosides GD1b and GT1b as receptors for BK virus. 2006 J. Virol. pmid:16415013
Murakami N et al. An adolescent with pharyngeal-cervical-brachial variant of Guillain-Barré syndrome after cytomegalovirus infection. 2006 Brain Dev. pmid:16368212
Wang XQ et al. Gangliosides inhibit urokinase-type plasminogen activator (uPA)-dependent squamous carcinoma cell migration by preventing uPA receptor/alphabeta integrin/epidermal growth factor receptor interactions. 2005 J. Invest. Dermatol. pmid:15816844
Boffey J et al. Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire. 2005 J. Neuroimmunol. pmid:15967512
Müthing J et al. Tumor-associated CD75s gangliosides and CD75s-bearing glycoproteins with Neu5Acalpha2-6Galbeta1-4GlcNAc-residues are receptors for the anticancer drug rViscumin. 2005 FASEB J. pmid:15520251
Jayaraman S et al. Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin. 2005 Proteins pmid:16104015
Yamaji K et al. [Internal ophthalmoplegia in acute oropharyngeal palsy with anti-GQ1b and anti-GT1a IgG antibodies]. 2005 No To Shinkei pmid:16026049
Hettmer S et al. Low complex ganglioside expression characterizes human neuroblastoma cell lines. 2005 Cancer Lett. pmid:15922866
Vukelić Z et al. Screening and sequencing of complex sialylated and sulfated glycosphingolipid mixtures by negative ion electrospray Fourier transform ion cyclotron resonance mass spectrometry. 2005 J. Am. Soc. Mass Spectrom. pmid:15792727
Higashi H and Chen NH Ganglioside/protein kinase signals triggering cytoskeletal actin reorganization. 2004 Glycoconj. J. pmid:14973370
Yowler BC and Schengrund CL Botulinum neurotoxin A changes conformation upon binding to ganglioside GT1b. 2004 Biochemistry pmid:15274627
Baksh MM et al. Detection of molecular interactions at membrane surfaces through colloid phase transitions. 2004 Nature pmid:14712272
Freire E et al. Sialic acid residues on astrocytes regulate neuritogenesis by controlling the assembly of laminin matrices. 2004 J. Cell. Sci. pmid:15292398
Mandal PK and Pettegrew JW Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment. 2004 Neurochem. Res. pmid:15002743
Nagashima T et al. Clinical correlates of serum anti-GT1a IgG antibodies. 2004 J. Neurol. Sci. pmid:15050449
Sugiyama N et al. [High-dose intravenous immunoglobulin therapy in a child case of Bickerstaff's brainstem encephalitis]. 2003 No To Hattatsu pmid:12875210