Ganglioside GT1

Ganglioside GT1 is a lipid of Sphingolipids (SP) class. Ganglioside gt1 is associated with abnormalities such as Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion and Neuritis. The involved functions are known as Binding (Molecular Function), Adjudication, Process, Drug Interactions and Macromolecular alteration. Ganglioside gt1 often locates in Entire nervous system, nucleocapsid location, Membrane, Face and cell body (neuron). The associated genes with Ganglioside GT1 are Homologous Gene, N-dodecyl-L-lysine amide, G-substrate, synthetic peptide and APP gene. The related lipids are GT1b-ganglioside, trisialaoganglioside GT1a, IV(4)-galactosyl-N-acetylganglioside GD1a, sialogangliosides and polysialoganglioside.

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Introduction

To understand associated biological information of Ganglioside GT1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ganglioside GT1?

Ganglioside GT1 is suspected in Neuropathy, Peripheral Neuropathy, Autoimmune Syndrome Type II, Polyglandular, protrusion, Neuritis, Gastrointestinal infections and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with Ganglioside GT1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ganglioside GT1?

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What functions are associated with Ganglioside GT1?


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What lipids are associated with Ganglioside GT1?

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What genes are associated with Ganglioside GT1?

Related references are published most in these journals:


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What common seen animal models are associated with Ganglioside GT1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ganglioside GT1

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Authors Title Published Journal PubMed Link
Yamamoto HA and Mohanan PV In vivo and in vitro effects of melatonin or ganglioside GT1B on L-cysteine-induced brain mitochondrial DNA damage in mice. 2003 Toxicol. Sci. pmid:12700404
Colarow L et al. Characterization and biological activity of gangliosides in buffalo milk. 2003 Biochim. Biophys. Acta pmid:12573454
Rapoport E et al. Ganglioside binding pattern of CD33-related siglecs. 2003 Bioorg. Med. Chem. Lett. pmid:12639556
Wang XQ et al. Ganglioside GM3 inhibits matrix metalloproteinase-9 activation and disrupts its association with integrin. 2003 J. Biol. Chem. pmid:12724312
Osanai T et al. Immunohistochemical and biochemical analyses of GD3, GT1b, and GQ1b gangliosides during neural differentiation of P19 EC cells. 2003 FEBS Lett. pmid:12606034
Yamamoto HA and Mohanan PV Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice. 2003 Brain Res. pmid:12573517
Velly LJ et al. Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: role of glutamate and its transporters. 2003 Anesthesiology pmid:12883409
Sugiyama N et al. [High-dose intravenous immunoglobulin therapy in a child case of Bickerstaff's brainstem encephalitis]. 2003 No To Hattatsu pmid:12875210
Onodera M et al. Acute isolated bulbar palsy with anti-GT1a IgG antibody subsequent to Campylobacter jejuni enteritis. 2002 J. Neurol. Sci. pmid:12409189
Woolf CJ and Bloechlinger S Neuroscience. It takes more than two to Nogo. 2002 Science pmid:12183616
Yamashita T et al. The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho. 2002 J. Cell Biol. pmid:12011108
Irvine AD et al. A colorimetric bead-binding assay for detection of intermolecular interactions. 2002 Exp. Dermatol. pmid:12366700
Alaedini A et al. Detection of anti-ganglioside antibodies in Guillain-Barré syndrome and its variants by the agglutination assay. 2002 J. Neurol. Sci. pmid:11959155
Orr CF et al. An inflammatory review of Parkinson's disease. 2002 Prog. Neurobiol. pmid:12531233
Gong Y et al. Localization of major gangliosides in the PNS: implications for immune neuropathies. 2002 Brain pmid:12390975
Mirkin BL et al. Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B. 2002 Cell Prolif. pmid:11952645
Schnaar RL et al. Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides. 2002 Anal. Biochem. pmid:11878808
Kanda N and Watanabe S Gangliosides GD1b, GT1b, and GQ1b enhance IL-2 and IFN-gamma production and suppress IL-4 and IL-5 production in phytohemagglutinin-stimulated human T cells. 2001 J. Immunol. pmid:11123278
Wang X et al. Carbohydrate-carbohydrate binding of ganglioside to integrin alpha(5) modulates alpha(5)beta(1) function. 2001 J. Biol. Chem. pmid:11118433
Bieberich E et al. Regulation of apoptosis during neuronal differentiation by ceramide and b-series complex gangliosides. 2001 J. Biol. Chem. pmid:11574545